Synthesis and bioaction of 2-alkyl-4(1h)-quinolone

Yaoxue Xuebao

Volumn 33, Issue 2, 1998, Pages 121-127

  Tang, Yuanqing ^a   Wu, Kemei ^a   Feng, Xiaozhang ^a   Huang, Liang ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

Antiulcer; Quinolone alkaloids; Synthesis; Vasorelaxant effect

Indexed keywords

ALKALOID; ANTIULCER AGENT; EVODIA FRUIT; QUINOLONE DERIVATIVE; VASODILATOR AGENT;

ANIMAL; ARTICLE; CHEMISTRY; ISOLATION AND PURIFICATION; RAT; SYNTHESIS;

ALKALOIDS; ANIMALS; ANTI-ULCER AGENTS; EVODIA; QUINOLONES; RATS; VASODILATOR AGENTS;

EID: 0032225780     PISSN: 05134870     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (6)

1. Tang YQ, Feng XZ, Huang L. Quinolone alkaloids from Evodia Rutaecarpa Bentham. Phytochemistry, 1996,43:719
2. Yamahara J, Kobayashi G, Matsuda H, et al. The vasorelaxant effect of evocarpine in isolated aortic strips: mode of action. Eur J Pharmacol, 1988,155: 139
3. Somanathan R, Smith KM. Synthesis of some 2-alkyl-4-quinolone and 2-alkyl-4-methoxyquinoline alkaloids. J Heterocycl Chem, 1981,18:1077
4. Coppola GM. The chemistry of 2H-3, 1-benzoxazine-2,4(1H)-dione (isatoc anhydride). 9. Synthesis of 2-arylquinoline alkaloids. J Heterocycl Chem, 1982,19: 727
5. Coppola GM. The chemistry of 2H-3, 1-benzoxazine-2,4(1H)-dione (isatoc anhydride). 17. Synthesis of 2-alkyl-4-quinolone alkaloids via a one-step reaction of N-methyl isatoic anhydride with methly ketone enolates. J Heterocycl Chem, 1985,22:491
6. Alvarez M, Salas M, Rigat L, et al. Hetero-ring lithiation of N-methyl-4-quinolone and N-methlyquinoline-4-thione. J Chem Soc Perkin Trans I, 1992,3:351