Coptisine exert cardioprotective effect through anti-oxidative and inhibition of RhoA/Rho kinase pathway on isoproterenol-induced myocardial infarction in rats

Atherosclerosis

Volumn 222, Issue 1, 2012, Pages 50-58

  Gong, Li Li ^a,b   Fang, Lian Hua ^a   Wang, Su Bo ^a   Sun, Jia Lin ^a   Qin, Hai Lin ^a   Li, Xiao Xiu ^a   Wang, Shou Bao ^a   Du, Guan Hua ^a  

^a INSTITUTE OF MATERIA MEDICA   (China)

^b CAPITAL MEDICAL UNIVERSITY   (China)

Author keywords

Anti oxidative; Coptisine; Isoproterenol; Mitochondrial respiratory function; Myocardial infarction; Rho kinase

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CARNITINE ACYLTRANSFERASE; COPTISINE; CREATINE KINASE; FASUDIL; GLUTATHIONE PEROXIDASE; ISOPRENALINE; LACTATE DEHYDROGENASE; MALONALDEHYDE; RHO KINASE; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SUPEROXIDE DISMUTASE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; ASPARTATE AMINOTRANSFERASE BLOOD LEVEL; CELL MEMBRANE; CONTROLLED STUDY; CREATINE KINASE BLOOD LEVEL; DRUG EFFECT; ENZYME INHIBITION; HEART FUNCTION; HEART INFARCTION; HEART MUSCLE CELL; HEART MUSCLE INJURY; HEART MUSCLE ISCHEMIA; HEART PROTECTION; LACTATE DEHYDROGENASE BLOOD LEVEL; MITOCHONDRIAL RESPIRATION; MORTALITY; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; Q WAVE; RAT; ST SEGMENT ELEVATION; TREATMENT DURATION;

1-(5-ISOQUINOLINESULFONYL)-2-METHYLPIPERAZINE; ANIMALS; ANTIOXIDANTS; APOPTOSIS; BERBERINE; CARDIOTONIC AGENTS; ISOPROTERENOL; MALE; MITOCHONDRIA, HEART; MYOCARDIAL INFARCTION; RATS; RATS, SPRAGUE-DAWLEY; RHO-ASSOCIATED KINASES; RHOA GTP-BINDING PROTEIN;

EID: 84862797401     PISSN: 00219150     EISSN: 18791484     Source Type: Journal    
DOI: 10.1016/j.atherosclerosis.2012.01.046     Document Type: Article

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