메뉴 건너뛰기




Volumn 23, Issue 3, 2012, Pages 280-287

Arsenic trioxide induces cervical cancer apoptosis, but specifically targets human papillomavirus-infected cell populations

Author keywords

Arsenic trioxide; Caspase 3; Cell cycle arrest; Flow cytometry; Human papillomavirus E6; p53

Indexed keywords

3 (4,5 DIMETHYL 2 THIAZOLYL) 2,5 DIPHENYLTETRAZOLIUM BROMIDE; ARSENIC TRIOXIDE; CASPASE 3; PROTEIN E6; PROTEIN P53;

EID: 84862796395     PISSN: 09594973     EISSN: 14735741     Source Type: Journal    
DOI: 10.1097/CAD.0b013e32834f1fd3     Document Type: Article
Times cited : (26)

References (42)
  • 1
    • 1542754943 scopus 로고    scopus 로고
    • The epidemiology of cervical cancer
    • Franco EL, Schlecht NF, Saslow D. The epidemiology of cervical cancer. Cancer J 2003; 9:348-359. (Pubitemid 44403488)
    • (2003) Cancer Journal , vol.9 , Issue.5 , pp. 348-359
    • Franco, E.L.1    Schlecht, N.F.2    Saslow, D.3
  • 2
    • 76149119429 scopus 로고    scopus 로고
    • Human papillomavirus types 16, 18, and 31 serostatus and prostate cancer risk in the Prostate Cancer Prevention Trial
    • Sutcliffe S, Viscidi RP, Till C, Goodman PJ, Hoque AM, Hsing AW, et al. Human papillomavirus types 16, 18, and 31 serostatus and prostate cancer risk in the Prostate Cancer Prevention Trial. Cancer Epidemiol Biomarkers Prev 2010; 19:614-618.
    • (2010) Cancer Epidemiol Biomarkers Prev , vol.19 , pp. 614-618
    • Sutcliffe, S.1    Viscidi, R.P.2    Till, C.3    Goodman, P.J.4    Hoque, A.M.5    Hsing, A.W.6
  • 3
    • 70350488933 scopus 로고    scopus 로고
    • Involvement of human papillomavirus in upper aero-digestive tracts cancers
    • Neufcoeur PE, Arafa M, Delvenne P, Saussez S. Involvement of human papillomavirus in upper aero-digestive tracts cancers. Bull Cancer 2009; 96:941-950.
    • (2009) Bull Cancer , vol.96 , pp. 941-950
    • Neufcoeur, P.E.1    Arafa, M.2    Delvenne, P.3    Saussez, S.4
  • 4
    • 72649083310 scopus 로고    scopus 로고
    • Infection of human papillomaviruses in cancers of different human organ sites
    • Shukla S, Bharti AC, Mahata S, Hussain S, Kumar R, Hedau S, et al. Infection of human papillomaviruses in cancers of different human organ sites. Indian J Med Res 2009; 130:222-233.
    • (2009) Indian J Med Res , vol.130 , pp. 222-233
    • Shukla, S.1    Bharti, A.C.2    Mahata, S.3    Hussain, S.4    Kumar, R.5    Hedau, S.6
  • 5
    • 33744756020 scopus 로고    scopus 로고
    • Papillomavirus genome structure, expression, and post-transcriptional regulation
    • DOI 10.2741/1971
    • Zheng ZM, Baker CC. Paillomavirus genome structure, expression, and post-transcriptional regulation. Front Biosci 2006; 11:2286-2302. (Pubitemid 43822560)
    • (2006) Frontiers in Bioscience , vol.11 , Issue.SUPPL. 1 , pp. 2286-2302
    • Zheng, Z.-M.1    Baker, C.C.2
  • 7
    • 0034024905 scopus 로고    scopus 로고
    • Is the human carcinogen arsenic carcinogenic to laboratory animals?
    • Huff J, Chan P, Nyska A. Is the human carcinogen arsenic carcinogenic to laboratory animals? Toxicol Sci 2000; 55:17-23. (Pubitemid 30252431)
    • (2000) Toxicological Sciences , vol.55 , Issue.1 , pp. 17-23
    • Huff, J.1    Chan, P.2    Nyska, A.3
  • 8
    • 0031137591 scopus 로고    scopus 로고
    • Delicious poison: Arsenic trioxide for the treatment of leukemia
    • Kwong YL, Todd D. Delicious poison: arsenic trioxide for the treatment of leukemia. Blood 1997; 89:3487-3488.
    • (1997) Blood , vol.89 , pp. 3487-3488
    • Kwong, Y.L.1    Todd, D.2
  • 10
    • 0033013777 scopus 로고    scopus 로고
    • Arsenic trioxide induces apoptosis of HPV16 DNA-immortalized human cervical epithelial cells and selectively inhibits viral gene expression
    • DOI 10.1002/(SICI)1097-0215(19990719)82:2<286::AID-IJC21>3.0.CO;2-K
    • Zheng J, Deng YP, Lin C, Fu M, Xiao PG, Wu M. Arsenic trioxide induces apoptosis of HPV16 DNA-immortalized human cervical epithelial cells and selectively inhibits viral gene expression. Int J Cancer 1999; 82: 286-292. (Pubitemid 29293790)
    • (1999) International Journal of Cancer , vol.82 , Issue.2 , pp. 286-292
    • Zheng, J.1    Deng, Y.-P.2    Lin, C.3    Fu, M.4    Xiao, P.-G.5    Wu, M.6
  • 12
    • 4744359324 scopus 로고    scopus 로고
    • Arsenic trioxide causes redistribution of cell cycle, caspase activation, and GADD expression in human colonic, breast, and pancreatic cancer cells
    • DOI 10.1081/CNV-200029068
    • Li X, Ding X, Adrian TE. Arsenic trioxide causes redistribution of cell cycle, caspase activation, and GADD expression in human colonic, breast, and pancreatic cancer cells. Cancer Invest 2004; 22:389-400. (Pubitemid 39310909)
    • (2004) Cancer Investigation , vol.22 , Issue.3 , pp. 389-400
    • Li, X.1    Ding, X.2    Adrian, T.E.3
  • 13
    • 29644436194 scopus 로고    scopus 로고
    • 3)-induced apoptosis in human glioblastoma cells
    • 3)-induced apoptosis in human glioblastoma cells. Cancer Sci 2005; 96:825-833.
    • (2005) Cancer Sci , vol.96 , pp. 825-833
    • Haga, N.1    Fujita, N.2    Tsuruo, T.3
  • 15
    • 34548497655 scopus 로고    scopus 로고
    • Human papillomavirus and cervical cancer
    • DOI 10.1016/S0140-6736(07)61416-0, PII S0140673607614160
    • Schiffman M, Castle PE, Jeronimo J, Rodriguez AC,Wacholder S. Human papillomavirus and cervical cancer. The Lancet 2007; 370:890-907. (Pubitemid 47371147)
    • (2007) Lancet , vol.370 , Issue.9590 , pp. 890-907
    • Schiffman, M.1    Castle, P.E.2    Jeronimo, J.3    Rodriguez, A.C.4    Wacholder, S.5
  • 16
    • 0024292712 scopus 로고
    • The human papillomavirus type 16 E7 gene encodes transactivation and transforming functions similar to adenovirus E1A
    • Phelps WC, Yee CL, Munger K, Howley PM. The human papillomavirus type 16 E7 gene encodes transactivation and transforming functions similar to adenovirus E1A. Cell 1988; 58:539-547.
    • (1988) Cell , vol.58 , pp. 539-547
    • Phelps, W.C.1    Yee, C.L.2    Munger, K.3    Howley, P.M.4
  • 17
    • 0029756780 scopus 로고    scopus 로고
    • p53-independent growth regulation of cervical cancer cells by the papillomavirus E6 oncogene
    • Spitkovsky D, Aengeneyndt F, Braspenning J, von Knebel Doeberitz M. p53- independent growth regulation of cervical cancer cells by the papillomavirus E6 oncogene. Oncogene 1996; 13:1027-1035. (Pubitemid 26329089)
    • (1996) Oncogene , vol.13 , Issue.5 , pp. 1027-1035
    • Spitkovsky, D.1    Aengeneyndt, F.2    Braspenning, J.3    Von Doeberitz, M.K.4
  • 18
    • 0025988293 scopus 로고
    • Degradation of p53 can be targeted by HPV E6 sequences distinct from those required for p53 binding and trans-activation
    • Crook T, Tidy JA, Vousden KH. Degradation of p53 can be targeted by HPV 16 sequences distinct from those required for p53 binding and transactivation. Cell 1991; 67:547-556. (Pubitemid 121001469)
    • (1991) Cell , vol.67 , Issue.3 , pp. 547-556
    • Crook, T.1    Tidy, J.A.2    Vousden, K.H.3
  • 19
    • 0025932933 scopus 로고
    • A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18
    • Huibregtse JM, Scheggner M, Howlet PM. A cellular protein mediates association of p53 with the E6 oncoprotein of human papillomavirus types 16 or 18. EMBO J 1991; 10:4129-4135. (Pubitemid 21905444)
    • (1991) EMBO Journal , vol.10 , Issue.13 , pp. 4129-4135
    • Huibregtse, J.M.1    Scheffner, M.2    Howley, P.M.3
  • 20
    • 0025639158 scopus 로고
    • The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53
    • Scheffner M, Werness BA, Huibregtse JM, Levine AJ, Howley PM. The E6 oncoprotein encoded by human papillomavirus types 16 and 18 promotes the degradation of p53. Cell 1990; 63:1129-1135.
    • (1990) Cell , vol.63 , pp. 1129-1135
    • Scheffner, M.1    Werness, B.A.2    Huibregtse, J.M.3    Levine, A.J.4    Howley, P.M.5
  • 21
    • 0024022067 scopus 로고
    • Comparison of the in vitro transforming activities of human papillomavirus types
    • Storey A, Pim D, Murray A, Osborn K, Banks L, Crawford L. Comparison of the in vitro transforming activities of human papillomavirus types. EMBO J 1988; 7:1815-1820.
    • (1988) EMBO J , vol.7 , pp. 1815-1820
    • Storey, A.1    Pim, D.2    Murray, A.3    Osborn, K.4    Banks, L.5    Crawford, L.6
  • 22
    • 0025271203 scopus 로고
    • Association of human papilomavirus type16 and 18 E6 protein with p53
    • Werness BA, Levine AJ, Howley PM. Association of human papilomavirus type16 and 18 E6 protein with p53. Science 1990; 248:76-79.
    • (1990) Science , vol.248 , pp. 76-79
    • Werness, B.A.1    Levine, A.J.2    Howley, P.M.3
  • 24
    • 0023322945 scopus 로고
    • Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines
    • Androphy EJ, Hubbert NL, Schiller JT, Lowy DR. Identification of the HPV-16 E6 protein from transformed mouse cells and human cervical carcinoma cell lines. EMBO J 1987; 6:989-992.
    • (1987) EMBO J , vol.6 , pp. 989-992
    • Androphy, E.J.1    Hubbert, N.L.2    Schiller, J.T.3    Lowy, D.R.4
  • 25
    • 0024368620 scopus 로고
    • The E6 and E7 genes of HPV-18 are sufficient for inducing two-stage in vitro transformation of human keratinocytes
    • Barbosa MS, Schlegel R. The E6 and E7 genes of HPV-18 are sufficient for inducing two-stage in vitro transformation of human keratinocytes. Oncogene 1989; 4:1529-1532. (Pubitemid 20008936)
    • (1989) Oncogene , vol.4 , Issue.12 , pp. 1529-1532
    • Barbosa, M.S.1    Schlegel, R.2
  • 26
    • 80051545459 scopus 로고    scopus 로고
    • Longterm impact of human papillomavirus vaccination on infection rates, cervical abnormalities, and cancer incidence
    • Bogaards JA, Coupé VM, Xiridou M, Meijer CJ,Wallinga J, Berkhof J. Longterm impact of human papillomavirus vaccination on infection rates, cervical abnormalities, and cancer incidence. Epidemiology 2011; 22:505-515.
    • (2011) Epidemiology , vol.22 , pp. 505-515
    • Bogaards, J.A.1    Coupé, V.M.2    Xiridou, M.3    Meijer, C.J.4    Wallinga, J.5    Berkhof, J.6
  • 28
    • 0010740572 scopus 로고    scopus 로고
    • 3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PMLRAR alpha/PML proteins
    • 3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PMLRAR alpha/PML proteins. Blood 1996; 88:1052-1061.
    • (1996) Blood , vol.88 , pp. 1052-1061
    • Chen, G.Q.1    Zhu, J.2    Shi, X.G.3    Ni, J.H.4    Zhong, H.J.5    Si, G.Y.6
  • 31
    • 78149450557 scopus 로고    scopus 로고
    • Arsenic trioxide induces apoptosis in uveal melanoma cells through the mitochondrial pathway
    • Chen MJ, Yang PY, Ye YZ, Hu DN, Chen MF. Arsenic trioxide induces apoptosis in uveal melanoma cells through the mitochondrial pathway. Am J Chin Med 2010; 38:1131-1142.
    • (2010) Am J Chin Med , vol.38 , pp. 1131-1142
    • Chen, M.J.1    Yang, P.Y.2    Ye, Y.Z.3    Hu, D.N.4    Chen, M.F.5
  • 32
    • 79952429308 scopus 로고    scopus 로고
    • Arsenic trioxide induces apoptosis of Burkitt lymphoma cell lines through multiple apoptotic pathways and triggers antiangiogenesis
    • Li HM, Long Y, Qing C, Yu M, Li ZH, Zhang XM, et al. Arsenic trioxide induces apoptosis of Burkitt lymphoma cell lines through multiple apoptotic pathways and triggers antiangiogenesis. Oncol Res 2011; 19:149-163.
    • (2011) Oncol Res , vol.19 , pp. 149-163
    • Li, H.M.1    Long, Y.2    Qing, C.3    Yu, M.4    Li, Z.H.5    Zhang, X.M.6
  • 34
    • 76649121191 scopus 로고    scopus 로고
    • Arsenic trioxide promotes mitochondrial DNA mutation and cell apoptosis in primary APL cells and NB4 cell line
    • Meng R, Zhou J, Sui M, Li Z, Feng G, Yang B. Arsenic trioxide promotes mitochondrial DNA mutation and cell apoptosis in primary APL cells and NB4 cell line. Sci China Life Sci 2010; 53:87-93.
    • (2010) Sci China Life Sci , vol.53 , pp. 87-93
    • Meng, R.1    Zhou, J.2    Sui, M.3    Li, Z.4    Feng, G.5    Yang, B.6
  • 35
    • 0037043118 scopus 로고    scopus 로고
    • Down-regulation of human papillomavirus E6/E7 oncogene by arsenic trioxide in cervical carcinoma cells
    • DOI 10.1016/S0304-3835(02)00039-3, PII S0304383502000393
    • Um SJ, Lee SY, Lim EJ, Myoung J, Namkoong SE, Park JS. Down-regulation of human papillomavirus E6/E7 oncogene by arsenic trioxide in cervical carcinoma cells. Cancer Let 2002; 181:11-22. (Pubitemid 34310657)
    • (2002) Cancer Letters , vol.181 , Issue.1 , pp. 11-22
    • Um, S.-J.1    Lee, S.-Y.2    Kim, E.-J.3    Myoung, J.4    Namkoong, S.-E.5    Park, J.-S.6
  • 36
    • 0036339964 scopus 로고    scopus 로고
    • Arsenic trioxide inhibits proliferation and induces apoptosis in pancreatic cancer cells
    • Li X, Ding X, Adrian TE. Arsenic trioxide inhibits proliferation and induces apoptosis in pancreatic cancer cells. Anticancer Res 2002; 22:2205-2213. (Pubitemid 34857044)
    • (2002) Anticancer Research , vol.22 , Issue.4 , pp. 2205-2213
    • Li, X.1    Ding, X.2    Adrian, T.E.3
  • 37
    • 0037192453 scopus 로고    scopus 로고
    • Arsenic trioxide-induced apoptosis through oxidative stress in cells of colon cancer cell lines
    • DOI 10.1016/S0024-3205(01)01545-4, PII S0024320501015454
    • Nakagawa Y, Akao Y, Morikawa H, Hirata I, Katsu K, Naoe T, et al. Arsenic trioxide-induced apoptosis through oxidative stress in cells of colon cancer cell lines. Life Sci 2002; 70:2253-2269. (Pubitemid 34251296)
    • (2002) Life Sciences , vol.70 , Issue.19 , pp. 2253-2269
    • Nakagawa, Y.1    Akao, Y.2    Morikawa, H.3    Hirata, I.4    Katsu, K.5    Naoe, T.6    Ohishi, N.7    Yagi, K.8
  • 38
    • 0030610687 scopus 로고    scopus 로고
    • Use of arsenic trioxide in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients
    • Shen Zx, Chen GQ, Ni JH, Li XS, Xiong SM, Qiu QY, et al. Use of arsenic trioxide in the treatment of acute promyelocytic leukemia (APL): II. Clinical efficacy and pharmacokinetics in relapsed patients. Blood 1997; 89:3354-3360.
    • (1997) Blood , vol.89 , pp. 3354-3360
    • Shen, Zx.1    Chen, G.Q.2    Ni, J.H.3    Li, X.S.4    Xiong, S.M.5    Qiu, Q.Y.6
  • 40
    • 0032933610 scopus 로고    scopus 로고
    • Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system
    • Dai J,Weinberg RS,Waxman S, Jing Y. Malignant cells can be sensitized to undergo growth inhibition and apoptosis by arsenic trioxide through modulation of the glutathione redox system. Blood 1999; 93:268-277. (Pubitemid 29019412)
    • (1999) Blood , vol.93 , Issue.1 , pp. 268-277
    • Dai, J.1    Weinberg, R.S.2    Waxman, S.3    Jing, Y.4
  • 41
    • 0026403583 scopus 로고
    • Oncoproteins encoded by the cancer-associated human papillomavirus target the products of the retinoblastoma and p53 tumor suppressor genes
    • Howley PM, Scheffner M, Huibregtse J, Minger K. Oncoproteins encoded by the cancer-associated human papillomavirus target the products of the retinoblastoma and p53 tumor suppressor genes. Cold Spring Harbor Symp. Quant Biol 1991; 56:149-155.
    • (1991) Cold Spring Harbor Symp. Quant Biol , vol.56 , pp. 149-155
    • Howley, P.M.1    Scheffner, M.2    Huibregtse, J.3    Minger, K.4
  • 42
    • 0029788134 scopus 로고    scopus 로고
    • Induction of apoptosis by p53 is independent of its oligomeric state and can be abolished by HPV-18 E6 through ubiquitin mediated degradation
    • Thomas M, Matlashewski G, Pim D, Banks L. Induction of apoptosis by p53 is independent of its oligomeric state and can be abolished by HPV-18 E6 through ubiquitin mediated degradation. Oncogene 1996; 123:265-273. (Pubitemid 26334858)
    • (1996) Oncogene , vol.13 , Issue.2 , pp. 265-273
    • Thomas, M.1    Matlashewski, G.2    Pim, D.3    Banks, L.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.