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Bioorganic and Medicinal Chemistry Letters

Volumn 22, Issue 7, 2012, Pages 2582-2584

Synthesis and evaluation of human phosphodiesterases (PDE) 5 inhibitor analogs as trypanosomal PDE inhibitors. Part 2. Tadalafil analogs

(7) Ochiana, Stefan O a Gustafson, Alden b Bland, Nicholas D b Wang, Cuihua a Russo, Michael J a Campbell, Robert K b Pollastri, Michael P a

a NORTHEASTERN UNIVERSITY (United States)

b MARINE BIOLOGICAL LABORATORY (United States)

Author keywords

Neglected disease; PDE5; Phosphodiesterase inhibitors; Tadalafil; Target repurposing; TbrPDEB1; Trypanosoma brucei

Indexed keywords

ANTITRYPANOSOMAL AGENT; PHOSPHODIESTERASE I; PHOSPHODIESTERASE V INHIBITOR; TADALAFIL;

AFRICAN TRYPANOSOMIASIS; ARTICLE; DRUG SCREENING; DRUG SYNTHESIS; ERECTILE DYSFUNCTION; NONHUMAN; TRYPANOSOMA BRUCEI; VIRULENCE;

ANIMALS; BIOLOGICAL ASSAY; CARBOLINES; HUMANS; PHOSPHODIESTERASE 5 INHIBITORS; PHOSPHORIC DIESTER HYDROLASES; PROTOZOAN PROTEINS; SOLUTIONS; STRUCTURE-ACTIVITY RELATIONSHIP; TRYPANOCIDAL AGENTS; TRYPANOSOMA BRUCEI BRUCEI;

TRYPANOSOMA BRUCEI;

EID: 84862796121 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2012.01.118 Document Type: Article

Times cited : (21)

References (14)

1
- 41849094126
- K. Stuart, R. Brun, S. Croft, A. Fairlamb, R.E. Gurtler, J. McKerrow, S. Reed, and R. Tarleton J. Clin. Invest. 118 2008 1301
- (2008) J. Clin. Invest. , vol.118 , pp. 1301
- Stuart, K.¹ Brun, R.² Croft, S.³ Fairlamb, A.⁴ Gurtler, R.E.⁵ McKerrow, J.⁶ Reed, S.⁷ Tarleton, R.⁸

2
- 73449135758
- R. Brun, J. Blum, F. Chappuis, and C. Burri Lancet 375 2010 148
- (2010) Lancet , vol.375 , pp. 148
- Brun, R.¹ Blum, J.² Chappuis, F.³ Burri, C.⁴

3
- 0034904388
- E. Matovu, T. Seebeck, J.C.K. Enyaru, and R. Kaminsky Microbes Infect. 3 2001 763
- (2001) Microbes Infect. , vol.3 , pp. 763
- Matovu, E.¹ Seebeck, T.² Enyaru, J.C.K.³ Kaminsky, R.⁴

4
- 33847368239
- M. Oberholzer, G. Marti, M. Baresic, S. Kunz, A. Hemphill, and T. Seebeck FASEB J. 21 2007 720
- (2007) FASEB J. , vol.21 , pp. 720
- Oberholzer, M.¹ Marti, G.² Baresic, M.³ Kunz, S.⁴ Hemphill, A.⁵ Seebeck, T.⁶

5
- 34548728165
- S. Laxman, and J.A. Beavo Mol. Interventions 7 2007 203
- (2007) Mol. Interventions , vol.7 , pp. 203
- Laxman, S.¹ Beavo, J.A.²

6
- 84862818022
- Y. Shakur, K.H.P. de, H. Ke, J. Kambayashi, and T. Seebeck Handb. Exp. Pharmacol. 2011 487
- (2011) Handb. Exp. Pharmacol. , pp. 487
- Shakur, Y.¹ De, K.H.P.² Ke, H.³ Kambayashi, J.⁴ Seebeck, T.⁵

7
- 82555165572
- N.D. Bland, C. Wang, C. Tallman, A.E. Gustafson, Z. Wang, T.D. Ashton, S.O. Ochiana, G. McAllister, K. Cotter, A.P. Fang, L. Gechijian, N. Garceau, R. Gangurde, R. Ortenberg, M.J. Ondrechen, R.K. Campbell, and M.P. Pollastri J. Med. Chem. 54 2011 8188
- (2011) J. Med. Chem. , vol.54 , pp. 8188
- Bland, N.D.¹ Wang, C.² Tallman, C.³ Gustafson, A.E.⁴ Wang, Z.⁵ Ashton, T.D.⁶ Ochiana, S.O.⁷ McAllister, G.⁸ Cotter, K.⁹ Fang, A.P.¹⁰ Gechijian, L.¹¹ Garceau, N.¹² Gangurde, R.¹³ Ortenberg, R.¹⁴ Ondrechen, M.J.¹⁵ Campbell, R.K.¹⁶ Pollastri, M.P.¹⁷

8
- 82555161767
- M.P. Pollastri, and R.K. Campbell Future Med. Chem. 3 2011 1307
- (2011) Future Med. Chem. , vol.3 , pp. 1307
- Pollastri, M.P.¹ Campbell, R.K.²

9
- 79960959242
- 10.1016/j.bmcl.2012.01.119
- C. Wang, T.D. Ashton, A. Gustafson, N.D. Bland, S.O. Ochiana, R.K. Campbell, and M.P. Pollastri Bioorg. Med. Chem. Lett. 2011 10.1016/j.bmcl.2012. 01.119
- (2011) Bioorg. Med. Chem. Lett.
- Wang, C.¹ Ashton, T.D.² Gustafson, A.³ Bland, N.D.⁴ Ochiana, S.O.⁵ Campbell, R.K.⁶ Pollastri, M.P.⁷

10
- 82555177172
- T. Seebeck, G.J. Sterk, and H. Ke Future Med. Chem. 3 2011 1289
- (2011) Future Med. Chem. , vol.3 , pp. 1289
- Seebeck, T.¹ Sterk, G.J.² Ke, H.³

11
- 79955825448
- T.B. Beghyn, J. Charton, F. Leroux, G. Laconde, A. Bourin, P. Cos, L. Maes, and B. Deprez J. Med. Chem. 54 2011 3222
- (2011) J. Med. Chem. , vol.54 , pp. 3222
- Beghyn, T.B.¹ Charton, J.² Leroux, F.³ Laconde, G.⁴ Bourin, A.⁵ Cos, P.⁶ Maes, L.⁷ Deprez, B.⁸

12
- 84862788320
- WO2008044144A2
- Deprez, B.; Beghyn, T.; Laconde, G.; Charton, J., 2008, WO2008044144A2.
- (2008)
- Deprez, B.¹ Beghyn, T.² Laconde, G.³ Charton, J.⁴

13
- 0041321268
- B.J. Sung, K.Y. Hwang, Y.H. Jeon, J.I. Lee, Y.S. Heo, J.H. Kim, J. Moon, J.M. Yoon, Y.L. Hyun, E. Kim, S.J. Eum, S.Y. Park, J.O. Lee, T.G. Lee, S. Ro, and J.M. Cho Nature 425 2003 98
- (2003) Nature , vol.425 , pp. 98
- Sung, B.J.¹ Hwang, K.Y.² Jeon, Y.H.³ Lee, J.I.⁴ Heo, Y.S.⁵ Kim, J.H.⁶ Moon, J.⁷ Yoon, J.M.⁸ Hyun, Y.L.⁹ Kim, E.¹⁰ Eum, S.J.¹¹ Park, S.Y.¹² Lee, J.O.¹³ Lee, T.G.¹⁴ Ro, S.¹⁵ Cho, J.M.¹⁶

14
- 84862785146
- H. Wang, Z. Yan, J. Geng, S. Kunz, T. Seebeck, and H. Ke Mol. Microbiol. 1029 2007 66
- (2007) Mol. Microbiol. , vol.1029 , pp. 66
- Wang, H.¹ Yan, Z.² Geng, J.³ Kunz, S.⁴ Seebeck, T.⁵ Ke, H.⁶

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