An integrated microfluidic system for rapid screening of alpha-fetoprotein-specific aptamers

Biosensors and Bioelectronics

Volumn 35, Issue 1, 2012, Pages 50-55

  Huang, Chao Jyun ^a   Lin, Hsin I ^a   Shiesh, Shu Chu ^a   Lee, Gwo Bin ^b  

^a NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^b NATIONAL TSING HUA UNIVERSITY   (Taiwan)

Author keywords

Alpha fetoprotein; Aptamer; Competitive assay; MEMS; Microfluidic; SELEX

Indexed keywords

ALPHA-FETOPROTEIN; APTAMERS; BINDING AFFINITIES; CLINICAL APPLICATION; HIGH AFFINITY; INTEGRATED MICROFLUIDIC SYSTEMS; ITERATIVE PROCESS; LINEAR DETECTION; LIVER CANCERS; RAPID SCREENING; SCREENING PROCESS; SCREENING TECHNIQUES; SELECTION PROCESS; SELEX; SINGLE-STRANDED DEOXYRIBONUCLEIC ACID; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENTS; TARGET ANALYTES; TARGET MOLECULE;

AMPLIFICATION; BINDING ENERGY; FLUIDIC DEVICES; MEMS; MICROFLUIDICS; MOLECULES; ORGANIC ACIDS; POLYMERASE CHAIN REACTION; RNA;

LIGANDS;

ALPHA FETOPROTEIN; PEPTIDE APTAMER; SINGLE STRANDED DNA;

ANALYTIC METHOD; ARTICLE; BIOCHIP; CONTROLLED STUDY; DNA SEQUENCE; GENE TARGETING; LIMIT OF DETECTION; LIVER CANCER; MICROFLUIDICS; MOLECULAR RECOGNITION; PROTEIN ANALYSIS; SYSTEMATIC EVOLUTION OF LIGANDS BY EXPONENTIAL ENRICHMENT;

ALPHA-FETOPROTEINS; APTAMERS, NUCLEOTIDE; BASE SEQUENCE; BINDING, COMPETITIVE; DNA, SINGLE-STRANDED; EQUIPMENT DESIGN; HUMANS; IMMUNOASSAY; LIVER NEOPLASMS; MICROFLUIDIC ANALYTICAL TECHNIQUES; SELEX APTAMER TECHNIQUE; TUMOR MARKERS, BIOLOGICAL;

EID: 84862791532     PISSN: 09565663     EISSN: 18734235     Source Type: Journal    
DOI: 10.1016/j.bios.2012.02.024     Document Type: Article

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