Drug interaction between cyclosporine and mTOR inhibitors in experimental model of chronic cyclosporine nephrotoxicity and pancreatic islet dysfunction

Transplantation

Volumn 93, Issue 4, 2012, Pages 383-389

  Piao, Shang Guo ^a,b   Bae, Soo Kyung ^a   Lim, Sun Woo ^a,b   Song, Ji Hyun ^a,b   Chung, Byung Ha ^a,b   Choi, Bum Soon ^a,b   Yang, Chul Woo ^a,b  

^a The Catholic University of Korea   (South Korea)

^b The Catholic University of Korea   (South Korea)

Author keywords

Cyclosporine A; Everolimus; Organ drug concentration; Pharmacokinetic interaction; Sirolimus

Indexed keywords

CYCLOSPORIN; EVEROLIMUS; RAPAMYCIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG TISSUE LEVEL; EXPERIMENTAL MODEL; KIDNEY INJURY; MALE; NEPHROTOXICITY; NONHUMAN; OXIDATIVE STRESS; PANCREAS INJURY; PANCREAS ISLET DISEASE; PRIORITY JOURNAL; RAT;

ANIMALS; APOPTOSIS; CYCLOSPORINE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG INTERACTIONS; ENZYME INHIBITORS; IMMUNOSUPPRESSIVE AGENTS; ISLETS OF LANGERHANS; KIDNEY; MALE; MODELS, ANIMAL; OXIDATIVE STRESS; RATS; RATS, SPRAGUE-DAWLEY; SIROLIMUS; TOR SERINE-THREONINE KINASES;

EID: 84862789600     PISSN: 00411337     EISSN: None     Source Type: Journal    
DOI: 10.1097/TP.0b013e3182421604     Document Type: Article

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