Identification of genetic risk variants for deep vein thrombosis by multiplexed next-generation sequencing of 186 hemostatic/pro-inflammatory genes

BMC Medical Genomics

Volumn 5, Issue , 2012, Pages

  Lotta, Luca A ^a,b   Wang, Mark ^b   Yu, Jin ^b   Martinelli, Ida ^a   Yu, Fuli ^b   Passamonti, Serena M ^a   Consonni, Dario ^a   Pappalardo, Emanuela ^a   Menegatti, Marzia ^a   Scherer, Steven E ^b   Lewis, Lora L ^b   Akbar, Humeira ^b   Wu, Yuanqing ^b   Bainbridge, Matthew N ^b   Muzny, Donna M ^b   Mannucci, Pier M ^a   Gibbs, Richard A ^b   Peyvandi, Flora ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

Author keywords

Deep vein thrombosis; DVT; FGA; heamostateome; multiplexing; next generation sequencing; rs6025; target capture; venous thromboembolism; VTE

Indexed keywords

GENOMIC DNA;

ADULT; ARTICLE; CONTROLLED STUDY; CYP4V2 GENE; DEEP VEIN THROMBOSIS; DNA BARCODING; F10 GENE; F11 GENE; F12 GENE; F13A GENE; F13B GENE; F2 GENE; F3 GENE; F5 GENE; F7 GENE; F8 GENE; F9 GENE; FEMALE; FGA GENE; FGB GENE; GENE; GENE FREQUENCY; GENE IDENTIFICATION; GENE POOL; GENE REPLICATION; GENETIC ASSOCIATION; GENETIC CODE; GENETIC RISK; GENETIC VARIABILITY; HUMAN; INTERMETHOD COMPARISON; MAJOR CLINICAL STUDY; MALE; MISSENSE MUTATION; MOLECULAR PATHOLOGY; NUCLEOTIDE SEQUENCE; OUTCOME ASSESSMENT; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROC GENE; PROS1 GENE; PROZ GENE; RISK ASSESSMENT; SEQUENCE ALIGNMENT; SEQUENCE ANALYSIS; SERPINC1 GENE; SINGLE NUCLEOTIDE POLYMORPHISM; CASE CONTROL STUDY; DNA SEQUENCE; GENETIC PREDISPOSITION; GENETICS; GENOMICS; HEMOSTASIS; HIGH THROUGHPUT SEQUENCING; INFLAMMATION; METHODOLOGY; PATHOPHYSIOLOGY; PILOT STUDY; VEIN THROMBOSIS;

ADULT; CASE-CONTROL STUDIES; FEMALE; GENETIC PREDISPOSITION TO DISEASE; GENETIC VARIATION; GENOMICS; HEMOSTASIS; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; INFLAMMATION; MALE; PILOT PROJECTS; SEQUENCE ANALYSIS, DNA; VENOUS THROMBOSIS;

EID: 84862788803     PISSN: None     EISSN: 17558794     Source Type: Journal    
DOI: 10.1186/1755-8794-5-7     Document Type: Article

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