Akebia saponin D attenuates ibotenic acid-induced cognitive deficits and pro-apoptotic response in rats: Involvement of MAPK signal pathway

Pharmacology Biochemistry and Behavior

Volumn 101, Issue 3, 2012, Pages 479-486

  Yu, Xing ^a   Wang, Lin Na ^a   Ma, Lin ^a   You, Ran ^a   Cui, Ran ^a   Ji, De ^a   Wu, Yue ^a   Zhang, Chun Feng ^a   Yang, Zhong Lin ^a   Ji, Hui ^a  

^a CHINA PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Akebia saponin D (ASD); Alzheimer's disease; Cholinergic deficit; Cognitive impairment; Ibotenic acid; Mitogen activated protein kinase (MAPK)

Indexed keywords

AKEBIA SAPONIN D; DONEPEZIL; IBOTENIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; NEUROPROTECTIVE AGENT; SAPONIN DERIVATIVE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BEHAVIOR; CHOLINERGIC SYSTEM; COGNITIVE DEFECT; CONTROLLED STUDY; DRUG ISOLATION; EXCITOTOXICITY; HIPPOCAMPUS; IN VIVO STUDY; LEARNING DISORDER; MALE; MEMORY DISORDER; NEUROPROTECTION; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; SIGNAL TRANSDUCTION;

ACETYLCHOLINE; ACETYLCHOLINESTERASE; ANIMALS; APOPTOSIS; BRAIN; CHOLINE O-ACETYLTRANSFERASE; COGNITION DISORDERS; DISEASE MODELS, ANIMAL; HIPPOCAMPUS; HUMANS; IBOTENIC ACID; MALE; MAP KINASE SIGNALING SYSTEM; MAZE LEARNING; MEMORY; NEUROPROTECTIVE AGENTS; RATS; RATS, SPRAGUE-DAWLEY; SAPONINS;

AKEBIA; RATTUS;

EID: 84862788346     PISSN: 00913057     EISSN: 18735177     Source Type: Journal    
DOI: 10.1016/j.pbb.2012.02.014     Document Type: Article

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