Synthesis of 3′-methoxy-E-diethylstilbestrol and its analogs as tumor angiogenesis inhibitors

Steroids

Volumn 77, Issue 5, 2012, Pages 419-423

  Liu, Qian ^a   Jin, Weiwei ^a   Zhu, Yan ^b   Zhou, Jieyun ^b   Lu, Min ^a   Zhang, Qian ^a  

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI INSTITUTE OF PLANNED PARENTHOOD RESEARCH   (China)

Author keywords

2 Methoxyestradiol; 3 Methoxy E diethylstilbestrol; Angiogenesis inhibitor; Metabolite; Non steroidal analog

Indexed keywords

2 METHOXYESTRADIOL; 3 (4 HYDROXY 3 METHOXYPHENYL) 4 (4 HYDROXYPHENYL)HEX 2 ENE; 3 (4 HYDROXY 3 METHOXYPHENYL) 4 (4 HYDROXYPHENYL)HEXANE (3' METHOXYDIETHYLDIHYDROSTILBESTROL); 3' METHOXYDIETHYLSTILBESTROL; 3' METHOXYDIETHYLSTILBESTROL DIBENZOATE; DIETHYLSTILBESTROL DERIVATIVE; UNCLASSIFIED DRUG; 3' METHOXY E DIETHYLSTILBESTROL; 3'-METHOXY-E-DIETHYLSTILBESTROL; ANGIOGENESIS INHIBITOR; DIETHYLSTILBESTROL; DRUG DERIVATIVE;

ANTIANGIOGENIC ACTIVITY; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; ARTICLE; CANCER CELL CULTURE; CYTOTOXICITY; DRUG SCREENING; DRUG SYNTHESIS; HUMAN; HUMAN CELL; CELL CULTURE; CELL PROLIFERATION; CHEMICAL MODEL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECT; IC 50; NEOPLASM; PATHOLOGY; STRUCTURE ACTIVITY RELATION; SYNTHESIS; TUMOR CELL LINE; UMBILICAL VEIN ENDOTHELIAL CELL; VASCULARIZATION; X RAY DIFFRACTION;

ANGIOGENESIS INHIBITORS; CELL LINE, TUMOR; CELL PROLIFERATION; CELLS, CULTURED; DIETHYLSTILBESTROL; DRUG SCREENING ASSAYS, ANTITUMOR; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; INHIBITORY CONCENTRATION 50; MODELS, CHEMICAL; MOLECULAR STRUCTURE; NEOPLASMS; STRUCTURE-ACTIVITY RELATIONSHIP; X-RAY DIFFRACTION;

EID: 84862786610     PISSN: 0039128X     EISSN: 18785867     Source Type: Journal    
DOI: 10.1016/j.steroids.2011.12.024     Document Type: Article

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