Concurrent transient activation of Wnt/β-catenin pathway prevents radiation damage to salivary glands

International Journal of Radiation Oncology Biology Physics

Volumn 83, Issue 1, 2012, Pages

  Hai, Bo ^a   Yang, Zhenhua ^a   Shangguan, Lei ^a   Zhao, Yanqiu ^a   Boyer, Arthur ^a   Liu, Fei ^a  

^a SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

Author keywords

Radiation; Salivary gland; Stem cells; Wnt catenin pathway; Xerostomia

Indexed keywords

BENEFICIAL EFFECTS; CATENIN SIGNALING; CELL ACTIVITY; HEAD AND NECK; HEAD-AND-NECK CANCER; MALE MOUSE; MRNA EXPRESSION; OVER-EXPRESSION; PHYSICAL DAMAGES; RADIATION-INDUCED; SALIVARY GLAND DYSFUNCTION; SALIVARY GLANDS; SINGLE-DOSE; SUBMANDIBULAR GLANDS; TRANSGENIC MICE; TRANSIENT EXPRESSION; UP-REGULATION; WNT PATHWAY; XEROSTOMIA;

CELL DEATH; GENES; HEAT RADIATION; MAMMALS; RADIATION; RADIATION DAMAGE; STEM CELLS;

RADIOTHERAPY;

BETA CATENIN; MESSENGER RNA; PUMA PROTEIN; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; FEMALE; HEAD AND NECK CANCER; HISTOPATHOLOGY; HYPOSALIVATION; IRRADIATION; MALE; MITOSIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RADIATION DOSE; RADIATION INJURY; SALIVA ANALYSIS; SALIVARY GLAND DISEASE; SEX DIFFERENCE; STEM CELL; SUBMANDIBULAR GLAND; UPREGULATION;

ACINAR CELLS; ANIMALS; APOPTOSIS; BETA CATENIN; CELL PROLIFERATION; FEMALE; MALE; MICE; MICE, TRANSGENIC; RADIATION INJURIES, EXPERIMENTAL; RNA, MESSENGER; SALIVARY GLANDS; SALIVATION; SEX FACTORS; SUBMANDIBULAR GLAND; WNT SIGNALING PATHWAY; WNT1 PROTEIN;

EID: 84862782491     PISSN: 03603016     EISSN: 1879355X     Source Type: Journal    
DOI: 10.1016/j.ijrobp.2011.11.062     Document Type: Article

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