Interactions between the ROP18 kinase and host cell proteins that aid in the parasitism of Toxoplasma gondii

Acta Tropica

Volumn 122, Issue 3, 2012, Pages 255-260

  Cheng, Li ^a   Chen, Ying ^a   Chen, Lijian ^a   Shen, Yuxian ^a   Shen, Jilong ^a   An, Ran ^a   Luo, Qingli ^a   Du, Jian ^a  

^a ANHUI MEDICAL UNIVERSITY   (China)

Author keywords

Host interaction; Proteins; ROP18; Toxoplasma gondii; Yeast two hybrid

Indexed keywords

BETA1 INTEGRIN; CELL PROTEIN; COMPLEMENTARY DNA; HYBRID PROTEIN; MYC PROTEIN; PROTEIN DDB1; PROTEIN DERL2; PROTEIN OCIAD1; PROTEIN ROP18; PROTEIN SERINE THREONINE KINASE; PROTEIN SLC3A2; PROTEIN TOR1AIP1; PROTEIN TPST2; UNCLASSIFIED DRUG;

ADHESION; DNA; PARASITE; PATHOGEN; PLASMID; PROTOZOAN;

ARTICLE; CELL ADHESION; CONTROLLED STUDY; DNA LIBRARY; DNA MODIFICATION; DNA REPAIR; HOST CELL; MATING; NONHUMAN; NUCLEOTIDE SEQUENCE; PARASITISM; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TOXOPLASMA GONDII; TRANSCRIPTION REGULATION; TWO HYBRID SYSTEM; YEAST CELL;

ANIMALS; HOST-PARASITE INTERACTIONS; HUMANS; MICE; MICE, INBRED BALB C; PROTEIN BINDING; PROTEIN INTERACTION MAPPING; PROTEIN-SERINE-THREONINE KINASES; TOXOPLASMA; TWO-HYBRID SYSTEM TECHNIQUES; VIRULENCE FACTORS;

TOXOPLASMA GONDII;

EID: 84862782038     PISSN: 0001706X     EISSN: 18736254     Source Type: Journal    
DOI: 10.1016/j.actatropica.2012.02.001     Document Type: Article

References (41)

1. Barillari G., Sgadari C., Palladino C., Gendelman R., Caputo A., Morris C.B., Nair B.C., Markham P., Nel A., Sturzl M., Ensoli B. Inflammatory cytokines synergize with the HIV-1 Tat protein to promote angiogenesis and Kaposi's sarcoma via induction of basic fibroblast growth factor and the alpha v beta 3 integrin. J. Immunol. 1999, 163:1929-1935.
2. Beisswanger R., Corbeil D., Vannier C., Thiele C., Dohrmann U., Kellner R., Ashman K., Niehrs C., Huttner W.B. Existence of distinct tyrosylprotein sulfotransferase genes: molecular characterization of tyrosylprotein sulfotransferase-2. Proc. Natl. Acad. Sci. U.S.A. 1998, 95:11134-11139.
3. Boothroyd J.C., Dubremetz J.F. Kiss and spit: the dual roles of Toxoplasma rhoptries. Nat. Rev. Microbiol. 2008, 6:79-88.
4. Carruthers V.B., Sibley L.D. Sequential protein secretion from three distinct organelles of Toxoplasma gondii accompanies invasion of human fibroblasts. Eur. J. Cell Biol. 1997, 73:114-123.
5. Chen X.G., Wu K., Lun Z.R. Toxoplasmosis researches in China. Chin. Med. J. (Engl.) 2005, 118:1015-1021.
6. Dechat T., Korbei B., Vaughan O.A., Vlcek S., Hutchison C.J., Foisner R. Lamina-associated polypeptide 2alpha binds intranuclear A-type lamins. J Cell Sci 2000, 113(Pt 19):3473-3484.
7. Dhe-Paganon S., Werner E.D., Chi Y.I., Shoelson S.E. Structure of the globular tail of nuclear lamin. J. Biol. Chem. 2002, 277:17381-17384.
8. Dubremetz J.F., Achbarou A., Bermudes D., Joiner K.A. Kinetics and pattern of organelle exocytosis during Toxoplasma gondii/host-cell interaction. Parasitol. Res. 1993, 79:402-408.
9. El Hajj H., Lebrun M., Arold S.T., Vial H., Labesse G., Dubremetz J.F. ROP18 is a rhoptry kinase controlling the intracellular proliferation of Toxoplasma gondii. PLoS Pathog. 2007, 3:e14.
10. Fentress S.J., Behnke M.S., Dunay I.R., Mashayekhi M., Rommereim L.M., Fox B.A., Bzik D.J., Taylor G.A., Turk B.E., Lichti C.F., Townsend R.R., Qiu W., Hui R., Beatty W.L., Sibley L.D. Phosphorylation of immunity-related GTPases by a Toxoplasma gondii-secreted kinase promotes macrophage survival and virulence. Cell Host Microbe 2010, 8:484-495.
11. Gao X.J., Zhao Z.J., He Z.H., Wang T., Yang T.B., Chen X.G., Shen J.L., Wang Y., Lv F.L., Hide G., Lun Z.R. Toxoplasma gondii infection in pregnant women in China. Parasitology 2011, 1-9.
12. Gomez-Marin J.E., de-la-Torre A., Angel-Muller E., Rubio J., Arenas J., Osorio E., Nunez L., Pinzon L., Mendez-Cordoba L.C., Bustos A., de-la-Hoz I., Silva P., Beltran M., Chacon L., Marrugo M., Manjarres C., Baquero H., Lora F., Torres E., Zuluaga O.E., Estrada M., Moscote L., Silva M.T., Rivera R., Molina A., Najera S., Sanabria A., Ramirez M.L., Alarcon C., Restrepo N., Falla A., Rodriguez T., Castano G. First Colombian multicentric newborn screening for congenital toxoplasmosis. PLoS Negl. Trop. Dis. 2011, 5:e1195.
13. Guerrero-Santoro J., Kapetanaki M.G., Hsieh C.L., Gorbachinsky I., Levine A.S., Rapic-Otrin V. The cullin 4B-based UV-damaged DNA-binding protein ligase binds to UV-damaged chromatin and ubiquitinates histone H2A. Cancer Res. 2008, 68:5014-5022.
14. He Y.J., McCall C.M., Hu J., Zeng Y., Xiong Y. DDB1 functions as a linker to recruit receptor WD40 proteins to CUL4-ROC1 ubiquitin ligases. Genes Dev. 2006, 20:2949-2954.
15. Hide G., Morley E.K., Hughes J.M., Gerwash O., Elmahaishi M.S., Elmahaishi K.H., Thomasson D., Wright E.A., Williams R.H., Murphy R.G., Smith J.E. Evidence for high levels of vertical transmission in Toxoplasma gondii. Parasitology 2009, 136:1877-1885.
16. Kapetanaki M.G., Guerrero-Santoro J., Bisi D.C., Hsieh C.L., Rapic-Otrin V., Levine A.S. The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:2588-2593.
17. Kondo Y., Kondoh J., Hayashi D., Ban T., Takagi M., Kamei Y., Tsuji L., Kim J., Yoneda Y. Molecular cloning of one isotype of human lamina-associated polypeptide 1s and a topological analysis using its deletion mutants. Biochem. Biophys. Res. Commun. 2002, 294:770-778.
18. Li J., Wang Q.E., Zhu Q., El-Mahdy M.A., Wani G., Praetorius-Ibba M., Wani A.A. DNA damage binding protein component DDB1 participates in nucleotide excision repair through DDB2 DNA-binding and cullin 4A ubiquitin ligase activity. Cancer Res. 2006, 66:8590-8597.
19. Marini F., Nardo T., Giannattasio M., Minuzzo M., Stefanini M., Plevani P., Muzi Falconi M. DNA nucleotide excision repair-dependent signaling to checkpoint activation. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:17325-17330.
20. Oda Y., Okada T., Yoshida H., Kaufman R.J., Nagata K., Mori K. Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. J. Cell Biol. 2006, 172:383-393.
21. Ohara T., Kawashiri S., Tanaka A., Noguchi N., Kitahara H., Okamune A., Kato K., Hase T., Nakaya H., Yoshizawa K. Integrin expression levels correlate with invasion, metastasis and prognosis of oral squamous cell carcinoma. Pathol. Oncol. Res. 2009, 15:429-436.
22. Ouyang Y.B., Moore K.L. Molecular cloning and expression of human and mouse tyrosylprotein sulfotransferase-2 and a tyrosylprotein sulfotransferase homologue in Caenorhabditis elegans. J. Biol. Chem. 1998, 273:24770-24774.
23. Peng H.J., Chen X.G., Lindsay D.S. A review: competence, compromise, and concomitance-reaction of the host cell to Toxoplasma gondii infection and development. J. Parasitol. 2011, 97:620-628.
24. Plattner F., Soldati-Favre D. Hijacking of host cellular functions by the Apicomplexa. Annu. Rev. Microbiol. 2008, 62:471-487.
25. Prager G.W., Feral C.C., Kim C., Han J., Ginsberg M.H. CD98hc (SLC3A2) interaction with the integrin beta subunit cytoplasmic domain mediates adhesive signaling. J. Biol. Chem. 2007, 282:24477-24484.
26. Saeij J.P., Boyle J.P., Boothroyd J.C. Differences among the three major strains of Toxoplasma gondii and their specific interactions with the infected host. Trends Parasitol. 2005, 21:476-481.
27. Saeij J.P., Boyle J.P., Coller S., Taylor S., Sibley L.D., Brooke-Powell E.T., Ajioka J.W., Boothroyd J.C. Polymorphic secreted kinases are key virulence factors in toxoplasmosis. Science 2006, 314:1780-1783.
28. Sengupta S., Michener C.M., Escobar P., Belinson J., Ganapathi R. Ovarian cancer immuno-reactive antigen domain containing 1 (OCIAD1), a key player in ovarian cancer cell adhesion. Gynecol. Oncol. 2008, 109:226-233.
29. Sheiner L., Soldati-Favre D. Protein trafficking inside Toxoplasma gondii. Traffic 2008, 9:636-646.
30. Sibley L.D., Boothroyd J.C. Virulent strains of Toxoplasma gondii comprise a single clonal lineage. Nature 1992, 359:82-85.
31. Steinfeldt T., Konen-Waisman S., Tong L., Pawlowski N., Lamkemeyer T., Sibley L.D., Hunn J.P., Howard J.C. Phosphorylation of mouse immunity-related GTPase (IRG) resistance proteins is an evasion strategy for virulent Toxoplasma gondii. PLoS Biol. 2010, 8:e1000576.
32. Sukthana Y. Toxoplasmosis: beyond animals to humans. Trends Parasitol. 2006, 22:137-142.
33. Sun N.K., Lu H.P., Chao C.C. Identification of rat DDB1, a putative DNA repair protein, and functional correlation with its damaged-DNA recognition activity. J. Biomed. Sci. 2002, 9:371-380.
34. Taylor S., Barragan A., Su C., Fux B., Fentress S.J., Tang K., Beatty W.L., Hajj H.E., Jerome M., Behnke M.S., White M., Wootton J.C., Sibley L.D. A secreted serine-threonine kinase determines virulence in the eukaryotic pathogen Toxoplasma gondii. Science 2006, 314:1776-1780.
35. Templeton T.J., Deitsch K.W. Targeting malaria parasite proteins to the erythrocyte. Trends Parasitol. 2005, 21:399-402.
36. Urbinati C., Bugatti A., Giacca M., Schlaepfer D., Presta M., Rusnati M. alpha(v)beta3-integrin-dependent activation of focal adhesion kinase mediates NF-kappaB activation and motogenic activity by HIV-1 Tat in endothelial cells. J. Cell Sci. 2005, 118:3949-3958.
37. Urbinati C., Mitola S., Tanghetti E., Kumar C., Waltenberger J., Ribatti D., Presta M., Rusnati M. Integrin alphavbeta3 as a target for blocking HIV-1 Tat-induced endothelial cell activation in vitro and angiogenesis in vivo. Arterioscler. Thromb. Vasc. Biol. 2005, 25:2315-2320.
38. Wang H., Zhai L., Xu J., Joo H.Y., Jackson S., Erdjument-Bromage H., Tempst P., Xiong Y., Zhang Y. Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. Mol. Cell 2006, 22:383-394.
39. Wang T., Liu M., Gao X.J., Zhao Z.J., Chen X.G., Lun Z.R. Toxoplasma gondii: the effects of infection at different stages of pregnancy on the offspring of mice. Exp. Parasitol. 2011, 127:107-112.
40. Wood R.D. DNA damage recognition during nucleotide excision repair in mammalian cells. Biochimie 1999, 81:39-44.
41. Yamamoto M., Ma J.S., Mueller C., Kamiyama N., Saiga H., Kubo E., Kimura T., Okamoto T., Okuyama M., Kayama H., Nagamune K., Takashima S., Matsuura Y., Soldati-Favre D., Takeda K. ATF6beta is a host cellular target of the Toxoplasma gondii virulence factor ROP18. J. Exp. Med. 2011, 208:1533-1546.