Sodium fluoride induces apoptosis in mouse embryonic stem cells through ROS-dependent and caspase- and JNK-mediated pathways

Toxicology and Applied Pharmacology

Volumn 259, Issue 3, 2012, Pages 329-337

  Nguyen Ngoc, Tam Dan ^a   Son, Young Ok ^b   Lim, Shin Saeng ^a   Shi, Xianglin ^b   Kim, Jong Ghee ^a   Heo, Jung Sun ^c   Choe, Youngji ^a   Jeon, Young Mi ^a   Lee, Jeong Chae ^a,b  

^a Chonbuk National University   (South Korea)

^b UNIVERSITY OF KENTUCKY   (United States)

^c Kyung Hee University   (South Korea)

Author keywords

Cell death; Cellular signaling; Mouse embryonic stem cells; ROS; Sodium fluoride

Indexed keywords

CATALASE; CYCLIN DEPENDENT KINASE 2; CYCLIN E; CYCLINE; FLUORIDE SODIUM; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 45 ALPHA; PROTEIN P53; REACTIVE OXYGEN METABOLITE; STRESS ACTIVATED PROTEIN KINASE; TRANSCRIPTION FACTOR; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CYCLE PROGRESSION; CELL CYCLE S PHASE; CELL MIGRATION; CELL POPULATION; CELL VIABILITY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DNA SYNTHESIS; EMBRYONIC STEM CELL; G2 PHASE CELL CYCLE CHECKPOINT; MITOCHONDRIAL MEMBRANE POTENTIAL; MOUSE; NONHUMAN; SIGNAL TRANSDUCTION;

ANIMALS; APOPTOSIS; CARIOSTATIC AGENTS; CATALASE; CELL SURVIVAL; DNA; DOSE-RESPONSE RELATIONSHIP, DRUG; EMBRYONIC STEM CELLS; G2 PHASE CELL CYCLE CHECKPOINTS; HYDROXYL RADICAL; JNK MITOGEN-ACTIVATED PROTEIN KINASES; M PHASE CELL CYCLE CHECKPOINTS; MEMBRANE POTENTIAL, MITOCHONDRIAL; MICE; REACTIVE OXYGEN SPECIES; SODIUM FLUORIDE;

EID: 84862779340     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2012.01.010     Document Type: Article

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