Effects of acute and chronic hyperglycemia on the neurochemical profiles in the rat brain with streptozotocin-induced diabetes detected using in vivo 1H MR spectroscopy at 9.4 T

Journal of Neurochemistry

Volumn 121, Issue 3, 2012, Pages 407-417

  Wang, Wen Tung ^a   Lee, Phil ^a,b   Yeh, Hung Wen ^a   Smirnova, Irina V ^a   Choi, In Young ^a,b  

^a UNIVERSITY OF KANSAS MEDICAL CENTER   (United States)

^b UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

Author keywords

diabetes; disease staging; glucose transport; magnetic resonance spectroscopy; streptozotocin; uncontrolled hyperglycemia

Indexed keywords

3 HYDROXYBUTYRIC ACID; 4 AMINOBUTYRIC ACID; ALANINE; ASCORBIC ACID; ASPARTIC ACID; CREATINE; CREATINE PHOSPHATE; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLUTATHIONE; GLYCEROPHOSPHORYLCHOLINE; INOSITOL; KETONE BODY; LACTIC ACID; N ACETYLASPARTIC ACID; N ACETYLASPARTYLGLUTAMIC ACID; PHOSPHOETHANOLAMINE; PHOSPHORYLCHOLINE; SERINE; TAURINE;

ANIMAL EXPERIMENT; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CORTEX; BRAIN METABOLISM; CHRONIC HYPERGLYCEMIA; CONTROLLED STUDY; GLUCOSE BRAIN LEVEL; GLUCOSE TRANSPORT; HIPPOCAMPUS; HYPERGLYCEMIA; IN VIVO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; MACROMOLECULE; MALE; METABOLITE; NON INVASIVE MEASUREMENT; NONHUMAN; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; STREPTOZOCIN DIABETES; TRANSPORT KINETICS;

ACUTE DISEASE; ALGORITHMS; ANIMALS; ASPARTIC ACID; BIOLOGICAL TRANSPORT, ACTIVE; BLOOD GLUCOSE; BLOOD-BRAIN BARRIER; BRAIN CHEMISTRY; CEREBRAL CORTEX; CHRONIC DISEASE; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; DISEASE PROGRESSION; GLUCOSE; GLUTATHIONE; HIPPOCAMPUS; HYPERGLYCEMIA; KINETICS; MAGNETIC RESONANCE SPECTROSCOPY; MALE; RATS; RATS, SPRAGUE-DAWLEY;

ANIMALIA; RATTUS;

EID: 84862778142     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2012.07698.x     Document Type: Article

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