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Volumn 98, Issue 6, 2012, Pages 443-449

Clinical applications of patient-specific induced pluripotent stem cells in cardiovascular medicine

Author keywords

[No Author keywords available]

Indexed keywords

1 [2 (6 METHYL 2 PYRIDYL)ETHYL] 4 (4 METHYLSULFONYLAMINOBENZOYL)PIPERIDINE; CALCIUM ION; NICORANDIL; NIFEDIPINE; PD 118057; PINACIDIL; POTASSIUM CHANNEL STIMULATING AGENT; RETROVIRUS VECTOR; UNCLASSIFIED DRUG;

EID: 84862777929     PISSN: 13556037     EISSN: 1468201X     Source Type: Journal    
DOI: 10.1136/heartjnl-2011-301317     Document Type: Review
Times cited : (50)

References (48)
  • 1
    • 33747195353 scopus 로고    scopus 로고
    • Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
    • DOI 10.1016/j.cell.2006.07.024, PII S0092867406009767
    • Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006;126:663-76. (Pubitemid 44233629)
    • (2006) Cell , vol.126 , Issue.4 , pp. 663-676
    • Takahashi, K.1    Yamanaka, S.2
  • 2
    • 67650034307 scopus 로고    scopus 로고
    • Prospects for pluripotent stem cell-derived cardiomyocytes in cardiac cell therapy and as disease models
    • Freund C, Mummery CL. Prospects for pluripotent stem cell-derived cardiomyocytes in cardiac cell therapy and as disease models. J Cell Biochem 2009;107:592-9.
    • (2009) J Cell Biochem , vol.107 , pp. 592-599
    • Freund, C.1    Mummery, C.L.2
  • 3
    • 79955583972 scopus 로고    scopus 로고
    • Derivation of human induced pluripotent stem cells for cardiovascular disease modeling
    • Narsinh K, Narsinh KH, Wu JC. Derivation of human induced pluripotent stem cells for cardiovascular disease modeling. Circ Res 2011;108:1146-56.
    • (2011) Circ Res , vol.108 , pp. 1146-1156
    • Narsinh, K.1    Narsinh, K.H.2    Wu, J.C.3
  • 4
    • 79955572417 scopus 로고    scopus 로고
    • Harnessing the potential of induced pluripotent stem cells for regenerative medicine
    • Wu SM, Hochedlinger K. Harnessing the potential of induced pluripotent stem cells for regenerative medicine. Nat Cell Biol 2011;13:497-505.
    • (2011) Nat Cell Biol , vol.13 , pp. 497-505
    • Wu, S.M.1    Hochedlinger, K.2
  • 5
    • 79955464098 scopus 로고    scopus 로고
    • The use of induced pluripotent stem cells in drug development
    • Inoue H, Yamanaka S. The use of induced pluripotent stem cells in drug development. Clin Pharmacol Ther 2011;89:655-61.
    • (2011) Clin Pharmacol Ther , vol.89 , pp. 655-661
    • Inoue, H.1    Yamanaka, S.2
  • 6
    • 58249110796 scopus 로고    scopus 로고
    • Induced pluripotent stem cells from a spinal muscular atrophy patient
    • Ebert AD, Yu J, Rose FF Jr, et al. Induced pluripotent stem cells from a spinal muscular atrophy patient. Nature 2009;457:277-80.
    • (2009) Nature , vol.457 , pp. 277-280
    • Ebert, A.D.1    Yu, J.2    Rose Jr., F.F.3
  • 7
    • 50149098605 scopus 로고    scopus 로고
    • Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons
    • Dimos JT, Rodolfa KT, Niakan KK, et al. Induced pluripotent stem cells generated from patients with ALS can be differentiated into motor neurons. Science 2008;321:1218-21.
    • (2008) Science , vol.321 , pp. 1218-1221
    • Dimos, J.T.1    Rodolfa, K.T.2    Niakan, K.K.3
  • 8
    • 79954626173 scopus 로고    scopus 로고
    • Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome
    • Liu GH, Barkho BZ, Ruiz S, et al. Recapitulation of premature ageing with iPSCs from Hutchinson-Gilford progeria syndrome. Nature 2011;472:221-5.
    • (2011) Nature , vol.472 , pp. 221-225
    • Liu, G.H.1    Barkho, B.Z.2    Ruiz, S.3
  • 9
    • 77957729169 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell models for long-QT syndrome
    • Moretti A, Bellin M, Welling A, et al. Patient-specific induced pluripotent stem-cell models for long-QT syndrome. N Engl J Med 2010;363:1397-409.
    • (2010) N Engl J Med , vol.363 , pp. 1397-1409
    • Moretti, A.1    Bellin, M.2    Welling, A.3
  • 10
    • 79952446402 scopus 로고    scopus 로고
    • Modelling the long QT syndrome with induced pluripotent stem cells
    • Itzhaki I, Maizels L, Huber I, et al. Modelling the long QT syndrome with induced pluripotent stem cells. Nature 2011;471:225-9.
    • (2011) Nature , vol.471 , pp. 225-229
    • Itzhaki, I.1    Maizels, L.2    Huber, I.3
  • 11
    • 79954523845 scopus 로고    scopus 로고
    • Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation
    • Matsa E, Rajamohan D, Dick E, et al. Drug evaluation in cardiomyocytes derived from human induced pluripotent stem cells carrying a long QT syndrome type 2 mutation. Eur Heart J 2011;32:952-62.
    • (2011) Eur Heart J , vol.32 , pp. 952-962
    • Matsa, E.1    Rajamohan, D.2    Dick, E.3
  • 12
    • 79952438377 scopus 로고    scopus 로고
    • Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome
    • Yazawa M, Hsueh B, Jia X, et al. Using induced pluripotent stem cells to investigate cardiac phenotypes in Timothy syndrome. Nature 2011;471:230-4.
    • (2011) Nature , vol.471 , pp. 230-234
    • Yazawa, M.1    Hsueh, B.2    Jia, X.3
  • 13
    • 77953443251 scopus 로고    scopus 로고
    • Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome
    • Carvajal-Vergara X, Sevilla A, D'Souza SL, et al. Patient-specific induced pluripotent stem-cell-derived models of LEOPARD syndrome. Nature 2010;465:808-12.
    • (2010) Nature , vol.465 , pp. 808-812
    • Carvajal-Vergara, X.1    Sevilla, A.2    D'Souza, S.L.3
  • 14
    • 84862784004 scopus 로고    scopus 로고
    • Generation of induced pluripotent stem cells and cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy
    • [abstract]. (A12906)
    • Ma D, Wei H, Guangqin Z, et al. Generation of induced pluripotent stem cells and cardiomyocytes as a cellular model of arrhythmogenic right ventricular cardiomyopathy [abstract]. Circulation 2011;124:21. Supplement (A12906).
    • (2011) Circulation , vol.124 , Issue.SUPPL. , pp. 21
    • Ma, D.1    Wei, H.2    Guangqin, Z.3
  • 15
    • 79955884032 scopus 로고    scopus 로고
    • Exogenous expression of human apoA-I enhances cardiac differentiation of pluripotent stem cells
    • Ng KM, Lee YK, Lai WH, et al. Exogenous expression of human apoA-I enhances cardiac differentiation of pluripotent stem cells. PLoS One 2011;6:e19787.
    • (2011) PLoS One , vol.6
    • Ng, K.M.1    Lee, Y.K.2    Lai, W.H.3
  • 16
    • 77955290927 scopus 로고    scopus 로고
    • Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells
    • Paige SL, Osugi T, Afanasiev OK, et al. Endogenous Wnt/beta-catenin signaling is required for cardiac differentiation in human embryonic stem cells. PLoS One 2010;5:e11134.
    • (2010) PLoS One , vol.5
    • Paige, S.L.1    Osugi, T.2    Afanasiev, O.K.3
  • 17
    • 79959866118 scopus 로고    scopus 로고
    • Engineering cell platforms for myocardial regeneration
    • Sarig U, Machluf M. Engineering cell platforms for myocardial regeneration. Expert Opin Biol Ther 2011;11:1055-77.
    • (2011) Expert Opin Biol Ther , vol.11 , pp. 1055-1077
    • Sarig, U.1    Machluf, M.2
  • 18
    • 77549085427 scopus 로고    scopus 로고
    • Biohybrid thin films for measuring contractility in engineered cardiovascular muscle
    • Alford PW, Feinberg AW, Sheehy SP, et al. Biohybrid thin films for measuring contractility in engineered cardiovascular muscle. Biomaterials 2010;31:3613-21.
    • (2010) Biomaterials , vol.31 , pp. 3613-3621
    • Alford, P.W.1    Feinberg, A.W.2    Sheehy, S.P.3
  • 19
    • 76749151845 scopus 로고    scopus 로고
    • Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes
    • Braam SR, Tertoolen L, van de Stolpe A, et al. Prediction of drug-induced cardiotoxicity using human embryonic stem cell-derived cardiomyocytes. Stem Cell Res 2010;4:107-16.
    • (2010) Stem Cell Res , vol.4 , pp. 107-116
    • Braam, S.R.1    Tertoolen, L.2    Van De Stolpe, A.3
  • 20
    • 60149107033 scopus 로고    scopus 로고
    • In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes
    • Caspi O, Itzhaki I, Kehat I, et al. In vitro electrophysiological drug testing using human embryonic stem cell derived cardiomyocytes. Stem Cells Dev 2009;18:161-72.
    • (2009) Stem Cells Dev , vol.18 , pp. 161-172
    • Caspi, O.1    Itzhaki, I.2    Kehat, I.3
  • 21
    • 79960095536 scopus 로고    scopus 로고
    • Concise review: Putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells
    • Collin J, Lako M. Concise review: putting a finger on stem cell biology: zinc finger nuclease-driven targeted genetic editing in human pluripotent stem cells. Stem Cells 2011;29:1021-33.
    • (2011) Stem Cells , vol.29 , pp. 1021-1033
    • Collin, J.1    Lako, M.2
  • 22
    • 80054987997 scopus 로고    scopus 로고
    • Targeted gene correction of alpha1-antitrypsin deficiency in induced pluripotent stem cells
    • Yusa K, Rashid ST, Strick-Marchand H, et al. Targeted gene correction of alpha1-antitrypsin deficiency in induced pluripotent stem cells. Nature 2011;478:391-4.
    • (2011) Nature , vol.478 , pp. 391-394
    • Yusa, K.1    Rashid, S.T.2    Strick-Marchand, H.3
  • 23
    • 80054918967 scopus 로고    scopus 로고
    • In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases
    • Sebastiano V, Maeder ML, Angstman JF, et al. In situ genetic correction of the sickle cell anemia mutation in human induced pluripotent stem cells using engineered zinc finger nucleases. Stem Cells 2011;29:1717-26.
    • (2011) Stem Cells , vol.29 , pp. 1717-1726
    • Sebastiano, V.1    Maeder, M.L.2    Angstman, J.F.3
  • 24
    • 77957319493 scopus 로고    scopus 로고
    • Cardiac stem cell therapy: Progress from the bench to bedside
    • Lovell MJ, Mathur A. Cardiac stem cell therapy: progress from the bench to bedside. Heart 2010;96:1531-7.
    • (2010) Heart , vol.96 , pp. 1531-1537
    • Lovell, M.J.1    Mathur, A.2
  • 25
    • 79151480328 scopus 로고    scopus 로고
    • IPS cells: A source of cardiac regeneration
    • Yoshida Y, Yamanaka S. iPS cells: a source of cardiac regeneration. J Mol Cell Cardiol 2011;50:327-32.
    • (2011) J Mol Cell Cardiol , vol.50 , pp. 327-332
    • Yoshida, Y.1    Yamanaka, S.2
  • 26
    • 79952261648 scopus 로고    scopus 로고
    • Stem cells: The dark side of induced pluripotency
    • Pera MF. Stem cells: the dark side of induced pluripotency. Nature 2011;471:46-7.
    • (2011) Nature , vol.471 , pp. 46-47
    • Pera, M.F.1
  • 27
    • 37549030199 scopus 로고    scopus 로고
    • Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin
    • Hanna J, Wernig M, Markoulaki S, et al. Treatment of sickle cell anemia mouse model with iPS cells generated from autologous skin. Science 2007;318:1920-3.
    • (2007) Science , vol.318 , pp. 1920-1923
    • Hanna, J.1    Wernig, M.2    Markoulaki, S.3
  • 29
    • 58849113643 scopus 로고    scopus 로고
    • Phenotypic correction of murine hemophilia A using an iPS cell-based therapy
    • Xu D, Alipio Z, Fink LM, et al. Phenotypic correction of murine hemophilia A using an iPS cell-based therapy. Proc Natl Acad Sci U S A 2009;106:808-13.
    • (2009) Proc Natl Acad Sci U S A , vol.106 , pp. 808-813
    • Xu, D.1    Alipio, Z.2    Fink, L.M.3
  • 30
    • 68249094138 scopus 로고    scopus 로고
    • Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells
    • Nelson TJ, Martinez-Fernandez A, Yamada S, et al. Repair of acute myocardial infarction by human stemness factors induced pluripotent stem cells. Circulation 2009;120:408-16.
    • (2009) Circulation , vol.120 , pp. 408-416
    • Nelson, T.J.1    Martinez-Fernandez, A.2    Yamada, S.3
  • 31
    • 80053508177 scopus 로고    scopus 로고
    • Induced pluripotent stem cell (iPSC)-derived Flk-1 progenitor cells engraft, differentiate, and improve heart function in a mouse model of acute myocardial infarction
    • Mauritz C, Martens A, Rojas SV, et al. Induced pluripotent stem cell (iPSC)-derived Flk-1 progenitor cells engraft, differentiate, and improve heart function in a mouse model of acute myocardial infarction. Eur Heart J 2011;32:2634-41.
    • (2011) Eur Heart J , vol.32 , pp. 2634-2641
    • Mauritz, C.1    Martens, A.2    Rojas, S.V.3
  • 33
    • 11244249952 scopus 로고    scopus 로고
    • Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: Insights into the development of cell-based pacemakers
    • DOI 10.1161/01.CIR.0000151313.18547.A2
    • Xue T, Cho HC, Akar FG, et al. Functional integration of electrically active cardiac derivatives from genetically engineered human embryonic stem cells with quiescent recipient ventricular cardiomyocytes: insights into the development of cell-based pacemakers. Circulation 2005;111:11-20. (Pubitemid 40070838)
    • (2005) Circulation , vol.111 , Issue.1 , pp. 11-20
    • Xue, T.1    Cho, H.C.2    Akar, F.G.3    Tsang, S.-Y.4    Jones, S.P.5    Marban, E.6    Tomaselli, G.F.7    Li, R.A.8
  • 35
    • 74049156859 scopus 로고    scopus 로고
    • Nongenetic method for purifying stem cell-derived cardiomyocytes
    • Hattori F, Chen H, Yamashita H, et al. Nongenetic method for purifying stem cell-derived cardiomyocytes. Nat Methods 2010;7:61-6.
    • (2010) Nat Methods , vol.7 , pp. 61-66
    • Hattori, F.1    Chen, H.2    Yamashita, H.3
  • 36
    • 84862826591 scopus 로고    scopus 로고
    • Direct reprogramming fibroblasts into endothelial cells
    • abstract
    • Margariti A, Winkler B, Karamariti E, et al. Direct reprogramming fibroblasts into endothelial cells [abstract]. Heart 2011;97:e7.
    • (2011) Heart , vol.97
    • Margariti, A.1    Winkler, B.2    Karamariti, E.3
  • 37
    • 79952273710 scopus 로고    scopus 로고
    • Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy
    • Efe JA, Hilcove S, Kim J, et al. Conversion of mouse fibroblasts into cardiomyocytes using a direct reprogramming strategy. Nat Cell Biol 2011;13:215-22.
    • (2011) Nat Cell Biol , vol.13 , pp. 215-222
    • Efe, J.A.1    Hilcove, S.2    Kim, J.3
  • 38
    • 77955321344 scopus 로고    scopus 로고
    • Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors
    • Ieda M, Fu JD, Delgado-Olguin P, et al. Direct reprogramming of fibroblasts into functional cardiomyocytes by defined factors. Cell 2010;142:375-86.
    • (2010) Cell , vol.142 , pp. 375-386
    • Ieda, M.1    Fu, J.D.2    Delgado-Olguin, P.3
  • 39
    • 78650085892 scopus 로고    scopus 로고
    • Proarrhythmic risk of embryonic stem cell-derived cardiomyocyte transplantation in infarcted myocardium
    • Liao SY, Liu Y, Siu CW, et al. Proarrhythmic risk of embryonic stem cell-derived cardiomyocyte transplantation in infarcted myocardium. Heart Rhythm 2010;7:1852-9.
    • (2010) Heart Rhythm , vol.7 , pp. 1852-1859
    • Liao, S.Y.1    Liu, Y.2    Siu, C.W.3
  • 40
    • 67249096636 scopus 로고    scopus 로고
    • Stem cell therapy for heart failure: Are arrhythmias a real safety concern?
    • Menasche P. Stem cell therapy for heart failure: are arrhythmias a real safety concern? Circulation 2009;119:2735-40.
    • (2009) Circulation , vol.119 , pp. 2735-2740
    • Menasche, P.1
  • 41
    • 70349661889 scopus 로고    scopus 로고
    • Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy
    • Johnston PV, Sasano T, Mills K, et al. Engraftment, differentiation, and functional benefits of autologous cardiosphere-derived cells in porcine ischemic cardiomyopathy. Circulation 2009;120:1075-83, 7.
    • (2009) Circulation , vol.120
    • Johnston, P.V.1    Sasano, T.2    Mills, K.3
  • 42
    • 70350514247 scopus 로고    scopus 로고
    • Cell sheet-based myocardial tissue engineering: New hope for damaged heart rescue
    • Shimizu T, Sekine H, Yamato M, et al. Cell sheet-based myocardial tissue engineering: new hope for damaged heart rescue. Curr Pharm Des 2009;15:2807-14.
    • (2009) Curr Pharm des , vol.15 , pp. 2807-2814
    • Shimizu, T.1    Sekine, H.2    Yamato, M.3
  • 43
    • 79954543387 scopus 로고    scopus 로고
    • A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability
    • Burridge PW, Thompson S, Millrod MA, et al. A universal system for highly efficient cardiac differentiation of human induced pluripotent stem cells that eliminates interline variability. PLoS One 2011;6:e18293.
    • (2011) PLoS One , vol.6
    • Burridge, P.W.1    Thompson, S.2    Millrod, M.A.3
  • 44
    • 79952050668 scopus 로고    scopus 로고
    • Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A
    • Fujiwara M, Yan P, Otsuji TG, et al. Induction and enhancement of cardiac cell differentiation from mouse and human induced pluripotent stem cells with cyclosporin-A. PLoS One 2011;6:e16734.
    • (2011) PLoS One , vol.6
    • Fujiwara, M.1    Yan, P.2    Otsuji, T.G.3
  • 45
    • 80054932328 scopus 로고    scopus 로고
    • Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease
    • Rufaihah AJ, Huang NF, Jame S, et al. Endothelial cells derived from human iPSCS increase capillary density and improve perfusion in a mouse model of peripheral arterial disease. Arterioscler Thromb Vasc Biol 2011;31:e72-9.
    • (2011) Arterioscler Thromb Vasc Biol , vol.31
    • Rufaihah, A.J.1    Huang, N.F.2    Jame, S.3
  • 46
    • 77955485961 scopus 로고    scopus 로고
    • Minimally-invasive implantation of living tissue engineered heart valves: A comprehensive approach from autologous vascular cells to stem cells
    • Schmidt D, Dijkman PE, Driessen-Mol A, et al. Minimally-invasive implantation of living tissue engineered heart valves: a comprehensive approach from autologous vascular cells to stem cells. J Am Coll Cardiol 2010;56:510-20.
    • (2010) J Am Coll Cardiol , vol.56 , pp. 510-520
    • Schmidt, D.1    Dijkman, P.E.2    Driessen-Mol, A.3
  • 47
    • 79958107062 scopus 로고    scopus 로고
    • Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection
    • Dick E, Matsa E, Young LE, et al. Faster generation of hiPSCs by coupling high-titer lentivirus and column-based positive selection. Nat Protoc 2011;6:701-14.
    • (2011) Nat Protoc , vol.6 , pp. 701-714
    • Dick, E.1    Matsa, E.2    Young, L.E.3
  • 48
    • 80055062731 scopus 로고    scopus 로고
    • Efficient generation of fully reprogrammed human iPS cells via polycistronic retroviral vector and a new cocktail of chemical compounds
    • Zhang Z, Gao Y, Gordon A, et al. Efficient generation of fully reprogrammed human iPS cells via polycistronic retroviral vector and a new cocktail of chemical compounds. PLoS One 2011;6:e26592.
    • (2011) PLoS One , vol.6
    • Zhang, Z.1    Gao, Y.2    Gordon, A.3


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