Blastic plasmacytoid dendritic cell neoplasm without cutaneous lesion at presentation: Case report and literature review

Acta Haematologica

Volumn 127, Issue 2, 2012, Pages 124-127

  Wang, Huijie ^a   Cao, Junning ^a   Hong, Xiaonan ^a  

^a FUDAN UNIVERSITY SHANGHAI CANCER CENTER   (China)

Author keywords

Chemotherapy; Dendritic cell neoplasm; Neoplasm

Indexed keywords

CD123 ANTIGEN; CD4 ANTIGEN; CD56 ANTIGEN; CYCLOPHOSPHAMIDE; CYTARABINE; DEXAMETHASONE; DOXORUBICIN; METHOTREXATE; URIC ACID; VINCRISTINE;

ADULT; BLAST CELL; BLASTIC PLASMACYTOID DENDRITIC CELL NEOPLASM; BONE MARROW BIOPSY; CANCER GROWTH; CANCER STAGING; CASE REPORT; CLINICAL FEATURE; COMPUTER ASSISTED TOMOGRAPHY; DISEASE DURATION; HEMATOLOGIC MALIGNANCY; HISTOPATHOLOGY; HUMAN; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; INGUINAL LYMPH NODE; LYMPH NODE BIOPSY; LYMPHADENOPATHY; LYMPHATIC LEUKEMIA; LYMPHOBLASTOMA; MALE; MYELOID LEUKEMIA; OVERALL SURVIVAL; PLASMACYTOID DENDRITIC CELL; PRIORITY JOURNAL; REVIEW; SARCOMA; SKIN DEFECT; TREATMENT RESPONSE; URIC ACID BLOOD LEVEL;

DENDRITIC CELLS; FATAL OUTCOME; HUMANS; LYMPHATIC DISEASES; LYMPHATIC METASTASIS; MALE; REMISSION INDUCTION; SKIN NEOPLASMS; YOUNG ADULT;

EID: 84862777229     PISSN: 00015792     EISSN: 14219662     Source Type: Journal    
DOI: 10.1159/000334703     Document Type: Review

References (23)

1. Vardiman JW, Thiele J, Arber DA, Brunning RD, Borowitz MJ, Porwit A, Harris NL, Le Beau MM, Hellström-Lindberg E, Tefferi A, Bloomfield CD: The 2008 revision of the World Health Organization (WHO) classification of myeloid neoplasms and acute leukemia: rationale and important changes. Blood 2009; 114: 937-951.
2. Bueno C, Almeida J, Lucio P, Marco J, Garcia R, de Pablos JM, Parreira A, Ramos F, Ruiz-Cabello F, Suarez-Vilela D, San Miguel JF, Orfao A: Incidence and characteristics of CD4+/HLA DR dendritic cell malignancies. Haematologica 2004; 89: 58-69. (Pubitemid 38165856)
3. Reimer P, Rudiger T, Kraemer D, Kunzmann V, Weissinger F, Zettl A, Konrad Müller-Hermelink H, Wilhelm M: What is CD4+CD56+ malignancy and how should it be reated? Bone Marrow Transplant 2003; 32: 637-646. (Pubitemid 37258618)
4. Bekkenk MW, Jansen PM, Meijer CJ, Willemze R: CD56+ hematological neoplasms presenting in the skin: a retrospective analysis of 23 new cases and 130 cases from the literature. Ann Oncol 2004; 15: 1097-1108. (Pubitemid 39089788)
5. Dalle S, Beylot-Barry M, Bagot M, Lipsker D, Machet L, Joly P, Dompmartin A, d'Incan M, Maubec E, Grange F, Dereure O, Prey S, Barete S, Wetterwald M, Fraitag S, Petrella T: Blastic plasmacytoid dendritic cell neoplasm: is transplantation the treatment of choice? Br J Dermatol 2009; 162: 74-79.
6. Eguaras AV, Lo RW, Veloso JD, Tan VG, Enriquez ML, Del Rosario ML: CD4+/CD56+hematodermic neoplasm: blastic NK cell lymphoma in a 6-year-old child: report of a case and review of literature. J Pediatr Hematol Oncol 2007; 29: 766-769. (Pubitemid 350071225)
7. Hu SC, Tsai KB, Chen GS, Chen PH: Infantile CD4+/CD56+ hematodermic neoplasm. Haematologica 2007; 92:e91-e93.
8. Adachi M, Maeda K, Takekawa M, Hinoda Y, Imai K, Sugiyama S, Yachi A: High expression of CD56 (N-CAM) in a patient with cutaneous CD4-positive lymphoma. Am J Hematol 1994; 47: 278-282. (Pubitemid 24372281)
9. Willemze R, Jaffe ES, Burg G, Cerroni L, Berti E, Swerdlow SH, Ralfkiaer E, Chimenti S, Diaz-Perez JL, Duncan LM, Grange F, Harris NL, Kempf W, Kerl H, Kurrer M, Knobler R, Pimpinelli N, Sander C, Santucci M, Sterry W, Vermeer MH, Wechsler J, Whittaker S, Meijer CJ: WHO-EORTC classification for cutaneous lymphomas. Blood 2005; 105: 3768-3785. (Pubitemid 40656118)
10. Lucio P, Parreira A, Orfao A: CD123 hi dendritic cell lymphoma: an unusual case of non-Hodgkin lymphoma. Ann Intern Med 1999; 131: 549-550. (Pubitemid 29482409)
11. Urosevic M, Conrada C, Kamarashev J, Asagoe K, Cozzio A, Burg G, Dummer R: CD4+CD56+ hematodermic neoplasms bear a plasmacytoid dendritic cell phenotype. Hum Pathol 2005; 36: 1020-1024. (Pubitemid 41253390)
12. Jaye DJ, Geigerman CM, Herling M, Eastburn K, Waller EK, Jones D: Expression of the plasmacytoid dendritic cell marker BDCA-2 supports a spectrum of maturation among CD4+ CD56+ hematodermic neoplasms. Mod Pathol 2006; 19: 1555-1562. (Pubitemid 44789923)
13. Pilichowska ME, Fleming MD, Pinkus JL, Pinkus GS: CD4+/CD56+ hematodermic neoplasm ('blastic natural killer cell lymphoma') neoplastic cells express the immature dendritic cell marker BDCA-2 and produce interferon. Am J Clin Pathol 2007; 128: 445-453. (Pubitemid 47479978)
14. Cota C, Vale E, Viana I, Requena L, Ferrara G, Anemona L, Metze D, Fink-Puches R, Wiesner T, Cerroni L: Cutaneous manifestations of blastic plasmacytoid dendritic cell neoplasm-morphologic and phenotypic variability in a series of 33 patients. Am J Surg Pathol 2010; 34: 75-87.
15. Nagatani T, Okazawa H, Kambara T, Satoh K, Tokura H, Miyazawa M, Yamada R, Baba N, Nakajima H, Yamazaki E, Kanamori H, Mohri H: Cutaneous monomorphous CD4-and CD56-positive large-cell lymphoma. Dermatology 2000; 200: 202-208. (Pubitemid 30265303)
16. Facchetti F, Ungari M, Marocolo D, Lonardi S, Vermi W: Blastic plasmacytoid dendritic cell neoplasm. Hematol Meet Rep 2009; 3: 1-3.
17. Cao W: Molecular characterization of human plasmacytoid dendritic cells. J Clin Immunol 2009; 29: 257-264.
18. Feuillard J, Jacob MC, Valensi F, Maynadié M, Gressin R, Chaperot L, Arnoulet C, Brignole-Baudouin F, Drénou B, Duchayne E, Falkenrodt A, Garand R, Homolle E, Husson B, Kuhlein E, Le Calvez G, Sainty D, Sotto MF, Trimoreau F, Béné MC: Clinical and biologic features of CD4+CD56+ malignancies. Blood 2002; 99: 1556-1563. (Pubitemid 34533026)
19. Tamura H, Ogata K, Mori S, An E, Tajika K, Sugisaki Y, Dan K: Lymphoblastic lymphoma of natural killer cell origin, presenting as pancreatic tumour. Histopathology 1998; 32: 508-511. (Pubitemid 28277550)
20. Ko YH, Kim SH, Ree HJ: Blastic NK-cell lymphoma expressing terminal deoxynucleotidyl transferase with Homer-Wright type pseudorosettes formation. Histopathology 1998; 33: 547-553. (Pubitemid 28563381)
21. Isobe K, Tamaru JI, Nakamura S, Itami J, Aruga T, Uno T, Yasuda S, Mikata A, Ito H: Blastic natural killer cell lymphoma arising from the mediastinum with terminal deoxynucleotidyl transferase expression. Pathol Int 2001; 51: 55-59. (Pubitemid 32158814)
22. Suzuki R, Nakamura S, Suzumiya J, Ichimura K, Ichikawa M, Ogata K, Kura Y, Aikawa K, Teshima H, Sako M, Kojima H, Nishio M, Yoshino T, Sugimori H, Kawa K, Oshimi K, NK-cell Tumor Study Group: Blastic natural killer cell lymphoma/leukemia (CD56-positive blastic tumor): prognostication and categorization according to anatomic sites of involvement. Cancer 2005; 104: 1022-1031. (Pubitemid 41170230)
23. Tsagarakis NJ, Kentrou NA, Papadimitriou KA, Pagoni M, Kokkini G, Papadaki H, Pappa V, Marinakis T, Anagnostopoulos NI, Vadikolia C, Anagnostopoulos A, Angelopoulou MK, Terpos E, Poziopoulos C, Anargyrou K, Rontogianni D, Papadaki T, Psarra A, Kontopidou FN, Skoumi D, Papadhimitriou SI, Paterakis G, Hellenic Dendritic Cell Leukemia Study Group: Acute lymphoplasmacytoid dendritic cell (DC2) leukemia: results from the Hellenic Dendritic Cell Leukemia Study Group. Leuk Res 2010; 34: 438-446.