CD4+/CD56+ hematodermic neoplasm: Blastic NK cell lymphoma in a 6-year-old child: Report of a case and review of literature

Journal of Pediatric Hematology/Oncology

Volumn 29, Issue 11, 2007, Pages 766-769

  Eguaras, Ann Veronique C ^a   Lo, Raymundo W ^c   Veloso, Januario D ^a,f   Tan, Vivian Grace ^d   Enriquez, Ma Luisa D ^b,e   Del Rosario, Ma Luz U ^a,e,g  

^a UNIVERSITY OF THE PHILIPPINES MANILA   (Philippines)

^b Physics Department   (Philippines)

^c Institute of Pathology   (Philippines)

^d Department of Dermatology ^*  (Philippines)

^e ST LUKE S MEDICAL CENTER   (Philippines)

^f National Kidney and Transplant Institute Philippines   (Philippines)

^g St Luke's Medical Centre   (Philippines)

Author keywords

Blastic natural killer cell lymphoma; Blastic NK cell lymphoma leukemia; CD4+CD56 + hematodermic neoplasm; Pediatric

Indexed keywords

ASPARAGINASE; CD4 ANTIGEN; CD56 ANTIGEN; DEXAMETHASONE; DOXORUBICIN; HEMOGLOBIN; LACTATE DEHYDROGENASE; METHOTREXATE; VINCRISTINE;

ANEMIA; ARTHRALGIA; ARTICLE; BLAST CELL CRISIS; BLOOD SMEAR; BONE MARROW; BONE MARROW BIOPSY; CASE REPORT; CELL INFILTRATION; CHROMOSOME ANALYSIS; COMPUTER ASSISTED TOMOGRAPHY; CONTUSION; DISEASE DURATION; FEMALE; FEVER; FLOW CYTOMETRY; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; IMMUNOPHENOTYPING; INGUINAL LYMPH NODE; KARYOTYPING; LACTATE DEHYDROGENASE BLOOD LEVEL; LYMPH NODE; LYMPHOCYTIC INFILTRATION; LYMPHOMA; MULTIPLE CYCLE TREATMENT; NATURAL KILLER CELL; NATURAL KILLER CELL LYMPHOMA; PRESCHOOL CHILD; PRIORITY JOURNAL; SKIN DEFECT; SKIN INDURATION; SKIN MANIFESTATION; THORAX RADIOGRAPHY;

ANTIGENS, CD4; ANTIGENS, CD56; CHILD; FEMALE; HUMANS; KILLER CELLS, NATURAL; PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; SKIN NEOPLASMS;

EID: 35948971767     PISSN: 10774114     EISSN: 15363678     Source Type: Journal    
DOI: 10.1097/MPH.0b013e318159a4e6     Document Type: Article

References (26)

1. Spits H, Lewis LL, Philippa JH. Development of Human T and natural killer cells. Blood. 1995;85:2654-2670.
2. Robertson MJ, Ritz J. Biology and clinical relevance of human natural killer cells. Blood. 1990;76:2421-2438.
3. Karube K, Ohshima K, Tsuchiya T, et al. Non-B, non-T neoplasms with lymphoblast morphology further clarification and classification. Am J Surg Pathol. 2003;27:1366-1374.
4. Kazuo O. Leukemia and lymphoma of natural killer lineage cells. Int J Hematol. 2003;78:1-6.
5. Massone C, Chott A, Metze D, et al. Subcutaneous, blastic natural killer (NK), NK/T- cell and other cytotoxic lymphomas of the skin: a morphologic, immunophenotypic and molecular study of 50 patients. Am J Surg Pathol. 2004;28:719-735.
6. Willemze R, Jaffe ES, Burg G, et al. WHO-EORTC classification for cutaneous lymphomas. Blood. 2005;105:3768-3785.
7. Hyakuna N, Toguchi S, Higa T, et al. Childhood blastic NK cell leukemia successfully treated with L-asparaginase and allogeneic bone marrow transplantation. Pediatr Blood Cancer. 2004;42:631-634.
8. Shaw P, Cohn S, Morgan E, et al. Natural killer cell lymphoma report of two pediatric cases, therapeutic options and review of the literature. Cancer. 2001;91:642-646.
9. + hematological neoplasms presenting in the skin: a retrospective analysis of 23 new cases and 130 cases from the literature. Ann Oncol. 2004;15:1097-1108.
10. Kaya E, Ozcan H, Kuku I, et al. Blastic natural killer cell leukemia with skin involvement: a case report. JEADV. 2004;18:86-88.
11. Falcao RP, Garcia AB, Marques MG, et al. Blastic CD4 NK cell leukemia/lymphoma: a distinct clinical entity. Leukemia Research. 2002;26:803-807.
12. Shinoda K, Muraki T, Yano M, et al. Infant leukemia suggestive of natural killer cell precursor origin followed an unusual clinical course. Acta Haematol. 2000;104:202-206.
13. + hematodermic neoplasms): a review. Am J Clin Pathol. 2005;123:662-675.
14. + malignancies. Blood. 2002;99:1556-1563.
15. + T-cell receptor silent peripheral T-cell lymphomas are natural killer cell lymphomas. Blood. 1996;87:1466-1473.
16. + myeloid natural killer cell precursor acute leukemia a distinct hematolymphoid disease entity. Blood. 1997;151:2417-2428.
17. Chaperot L, Bendriss N, Manches O, et al. Identification of a leukemic counterpart of the plasmacytoid dendritic cells. Blood. 2001;97:3210-3216.
18. + DC2 acute leukemia is characterized by recurrent clonal chromosomal changes affecting 6 major targets: a study of 21 cases by the Groupe Francais de Cytogenetique Hematologique. Blood. 2002;99:4154-4159.
19. Yamada O, Ichikawa M, Okamoto T, et al. Killer T-cell induction in patients with blastic natural killer cell lymphoma/leukemia: implications for successful treatment and possible therapeutic strategies. Br J Haematol. 2001;113:153-160.
20. +: a clinicopathologic study of 49 cases of an uncommon aggressive neoplasm. Blood. 1997;89:4501-4513.
21. Bayerl MG, Rakozy CK, Mohamed AN, et al. Blastic natural killer cell lymphoma/leukemia a report of seven cases. Am J Clin Pathol. 2002;117:41-50.
22. Savoia P, Fierro M, Novelli M, et al. CD56-positive cutaneous lymphoma: a poorly recognized entity in the spectrum of primary cutaneous disease. Br J Dermatol. 1997;117:966-971.
23. + blastic natural killer cell tumor of the skin, a primitive systemic malignancy related to myelomonocytic leukemia. Cancer. 2002;94:2401-2408.
24. Kasakov D, Mentzel T, Burg G, et al. Blastic natural killer-cell lymphoma of the skin associated with myelodysplastic syndrome or myelogenous leukemia: a coincidence or more? Br J Dermatol. 2003;149:869-876.
25. Ohnuma K, Toyoda Y, Nishihira H, et al. Aggressive natural killer (NK) cell lymphoma: report of a pediatric case and review of the literature. Leukemia Lymphoma. 1997;25:387-392.
26. Suminoe A, Matsuzaki A, Takada H, et al. An infant with precursor natural killer (NK) cell leukemia successfully treated with an unrelated cord blood transplantation. Leukemia Lymphoma. 2000;39:641-646.