The Formation and Stability of DC-SIGN Microdomains Require its Extracellular Moiety

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Volumn 13, Issue 5, 2012, Pages 715-726

  Liu, Ping ^a   Wang, Xiang ^b   Itano, Michelle S ^a   Neumann, Aaron K ^a   Jacobson, Ken ^a   Thompson, Nancy L ^b  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

^b University of North Carolina at Chapel Hill   (United States)

Author keywords

Antigen presentation; CD209; Extracellular matrix; Fluorescence recovery after photobleaching; Live cell fluorescence imaging; Membrane microdomain; Membrane protein dynamics; Pathogen uptake

Indexed keywords

CALCIUM; CARBOHYDRATE BINDING PROTEIN; CD209 ANTIGEN;

ARTICLE; BLEACHING; CARBOHYDRATE RECOGNITION DOMAIN; CELL ADHESION; CELL SURFACE; CELLULAR DISTRIBUTION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; CYTOPLASM; DIFFUSION; FLUORESCENCE; GLYCOSYLATION; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN MODIFICATION; PROTEIN STABILITY; PROTEIN STRUCTURE; TANDEM REPEAT;

AMINO ACID MOTIFS; ANIMALS; ANTIGENS, CD; CALCIUM; CARBOHYDRATES; CELL ADHESION; CELL ADHESION MOLECULES; CYTOSKELETON; EXTRACELLULAR MATRIX; GLYCOSYLATION; HUMANS; LECTINS, C-TYPE; MICE; MODELS, BIOLOGICAL; MUTATION; NIH 3T3 CELLS; PROTEIN STRUCTURE, TERTIARY; RECEPTORS, CELL SURFACE; SIGNAL TRANSDUCTION;

EID: 84862777193     PISSN: 13989219     EISSN: 16000854     Source Type: Journal    
DOI: 10.1111/j.1600-0854.2012.01337.x     Document Type: Article

References (36)

1. Geijtenbeek TB, den Dunnen J, Gringhuis SI. Pathogen recognition by DC-SIGN shapes adaptive immunity. Future Microbiol 2009;4:879-890.
2. Snyder GA, Ford J, Torabi-Parizi P, Arthos JA, Schuck P, Colonna M, Sun PD. Characterization of DC-SIGN/R interaction with human immunodeficiency virus type 1 gp120 and ICAM molecules favors the receptor's role as an antigen-capturing rather than an adhesion receptor. J Virol 2005;79:4589-4598.
3. Cambi A, de Lange F, van Maarseveen NM, Nijhuis M, Joosten B, van Dijk EMHP, de Bakker BI, Fransen JAM, Bovee-Geurts PHM, van Leeuwen FN, Van Hulst NF, Figdor CG. Microdomains of the C-type lectin DC-SIGN are portals for virus entry into dendritic cells. J Cell Biol 2004;164:145-155.
4. Koopman M, Cambi A, de Bakker BI, Joosten B, Figdor CG, van Hulst NF, Garcia-Parajo MF. Near-field scanning optical microscopy in liquid for high resolution single molecule detection on dendritic cells. FEBS Lett 2004;573:6-10.
5. Neumann AK, Thompson NL, Jacobson K. Distribution and lateral mobility of DC-SIGN on immature dendritic cells-implications for pathogen uptake. J Cell Sci 2008;121:634-643.
6. Cambi A, Koopman M, Figdor CG. How C-type lectins detect pathogens. Cell Microbiol 2005;7:481-488.
7. Itano MS, Neumann AK, Liu P, Zhang F, Gratton E, Parak WJ, Thompson NL, Jacobson K. DC-SIGN and influenza hemagglutinin dynamics in plasma membrane microdomains are markedly different. Biophys J 2011;100:2662-2670.
8. Zuckerman DM, Hicks SW, Charron G, Hang HC, Machamer CE. Differential regulation of two palmitoylation sites in the cytoplasmic tail of the beta1-adrenergic receptor. J Biol Chem 2011;286:19014-19023.
9. Chapple JP, Hardcastle AJ, Grayson C, Willison KR, Cheetham ME. Delineation of the plasma membrane targeting domain of the X-linked retinitis pigmentosa protein RP2. Invest Ophthalmol Vis Sci 2002;43:2015-2020.
10. Webb Y, Hermida-Matsumoto L, Resh MD. Inhibition of protein palmitoylation, raft localization, and T cell signaling by 2-bromopalmitate and polyunsaturated fatty Acids. J Biol Chem 2000;275:261-270.
11. Liu P, Sudhaharan T, Koh RM, Hwang LC, Ahmed S, Maruyama IN, Wohland T. Investigation of the dimerization of proteins from the epidermal growth factor receptor family by single wavelength fluorescence cross-correlation spectroscopy. Biophys J, 2007; 93: 684-698.
12. Caparrós E, Munoz P, Sierra-Filardi E, Serrano-Gómez D, Puig-Kröger A, Rodríguez-Fernández JL, Mellado M, Sancho J, Zubiaur M, Corbí AL. DC-SIGN ligation on dendritic cells results in ERK and PI3K activation and modulates cytokine production. Blood 2006;107:3950-3958.
13. Curtis BM, Scharnowske S, Watson AJ. Sequence and expression of a membrane-associated C-type lectin that exhibits CD4-independent binding of human immunodeficiency virus envelope glycoprotein gp120. Proc Natl Acad Sci U S A 1992;89:8356-8360.
14. Vasta GR. Roles of galectins in infection. Nat Rev Microbiol 2009;7:424-438.
15. Serrano-Gómez D, Sierra-Filardi E, Martínez-Nuñez RT, Caparrós E, Delgado R, Muñoz-Fernández MA, Abad MA, Jimenez-Barbero J, Leal M, Corbí AL. Structural requirements for multimerization of the pathogen receptor dendritic cell-specific ICAM3-grabbing non-integrin (CD209) on the cell surface. J Biol Chem 2008;283:3889-3903.
16. Sprague BL, McNally JG. FRAP analysis of binding: proper and fitting. Trends Cell Biol 2005;15:84-91.
17. Lippincott-Schwartz J, Snapp E, Kenworthy A. Studying protein dynamics in living cells. Nat Rev Mol Cell Biol 2001;2:444-456.
18. Baumgart T, Hammond AT, Sengupta P, Hess ST, Holowka DA, Baird BA, Webb WW. Large-scale fluid/fluid phase separation of proteins and lipids in giant plasma membrane vesicles. Proc Natl Acad Sci U S A 2007;104:3165-3170.
19. Keller H, Lorizate M, Schwille P. PI(4, 5)P2 degradation promotes the formation of cytoskeleton-free model membrane systems. Chemphyschem 2009;10:2805-2812.
20. Itano MS, Steinhauer C, Schmied J, Forthmann C, Liu P, Neumann AK, Thompson NL, Tinnefeld P, Jacobson K. Super-Resolution Imaging of C-Type Lectin and Influenza Hemagglutinin Nanodomains on Plasma Membranes using Blink Microscopy. Biophys J 2012:102: in press.
21. Gringhuis SI, den Dunnen J, Litjens M, van der Vlist M, Geijtenbeek TBH. Carbohydrate-specific signaling through the DC-SIGN signalosome tailors immunity to Mycobacterium tuberculosis, HIV-1 and Helicobacter pylori. Nat Immunol 2009;10:1081-1088.
22. Hodges A, Sharrocks K, Edelmann M, Baban D, Moris A, Schwartz O, Drakesmith H, Davies K, Kessler B, McMichael A, Simmons A. Activation of the lectin DC-SIGN induces an immature dendritic cell phenotype triggering Rho-GTPase activity required for HIV-1 replication. Nat Immunol 2007;8:569-577.
23. Feinberg H, Guo Y, Mitchell DA, Drickamer K, Weis WI. Extended neck regions stabilize tetramers of the receptors DC-SIGN and DC-SIGNR. J Biol Chem 2005;280:1327-1335.
24. Yu QD, Oldring AP, Powlesland AS, Tso CKW, Yang C, Drickamer K, Taylor ME. Autonomous tetramerization domains in the glycan-binding receptors DC-SIGN and DC-SIGNR. J Mol Biol 2009;387:1075-1080.
25. Horejsi V, Zhang W, Schraven B. Transmembrane adaptor proteins: organizers of immunoreceptor signalling. Nat Rev Immunol 2004;4:603-616.
26. Rapraeger AC. Syndecan-regulated receptor signaling. J Cell Biol 2000;149:995-998.
27. Avota E, Gulbins E, Schneider-Schaulies S. DC-SIGN mediated sphingomyelinase-activation and ceramide generation is essential for enhancement of viral uptake in dendritic cells. PLoS Pathog 2011;7:e1001290.
28. Gumbiner BM. Regulation of cadherin-mediated adhesion in morphogenesis. Nat Rev Mol Cell Biol 2005;6:622-634.
29. Sanes JR. The basement membrane/basal lamina of skeletal muscle. J Biol Chem 2003;278:12601-12604.
30. Dubash AD, Menold MM, Samson T, Boulter E, García-Mata R, Doughman R, Burridge K. Chapter 1 focal adhesions: new angles on an old structure. Int Rev Cell Mol Biol 2009;277:1-65.
31. O'Reilly MK, Paulson JC. Siglecs as targets for therapy in immune-cell-mediated disease. Trends Pharmacol Sci 2009;30:240-248.
32. Crocker PR, Paulson JC, Varki A. Siglecs and their roles in the immune system. Nat Rev Immunol 2007;7:255-266.
33. Guo Y, Feinberg H, Conroy E, Mitchell DA, Alvarez R, Blixt O, Taylor ME, Weis WI, Drickamer K. Structural basis for distinct ligand-binding and targeting properties of the receptors DC-SIGN and DC-SIGNR. Nat Struct Mol Biol 2004;11:591-598.
34. Pohlmann S, Baribaud F, Lee B, Leslie GJ, Sanchez MD, Hiebenthal-Millow K, Munch J, Kirchhoff F, Doms RW. DC-SIGN interactions with human immunodeficiency virus type 1 and 2 and simian immunodeficiency virus. J Virol 2001;75:4664-4672.
35. Localizer-localization microscopy toolkit (Version 1.0) [computer software], 2011, retrieved June 2011, from:
36. Serge A, Bertaux N, Rigneault H, Marguet D. Dynamic multiple-target tracing to probe spatiotemporal cartography of cell membranes. Nat Methods 2008;5:687-694.