메뉴 건너뛰기




Volumn 680, Issue 1-3, 2012, Pages 34-40

Beta-asarone attenuates ischemia-reperfusion-induced autophagy in rat brains via modulating JNK, p-JNK, Bcl-2 and Beclin 1

Author keywords

asarone; Autophagy; Beclin 1; Ischemia reperfusion; JNK

Indexed keywords

BECLIN 1; BETA ASARONE; NEURON SPECIFIC ENOLASE; PROTEIN BCL 2; SP 1600125; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE INHIBITOR; UNCLASSIFIED DRUG;

EID: 84862776587     PISSN: 00142999     EISSN: 18790712     Source Type: Journal    
DOI: 10.1016/j.ejphar.2012.01.016     Document Type: Article
Times cited : (62)

References (37)
  • 1
    • 38049115875 scopus 로고    scopus 로고
    • Apoptosis and autophagy: Regulatory connections between two supposedly different processes
    • T. Andrew Apoptosis and autophagy: regulatory connections between two supposedly different processes Apoptosis 13 1 2008 1 9
    • (2008) Apoptosis , vol.13 , Issue.1 , pp. 1-9
    • Andrew, T.1
  • 2
    • 2442530401 scopus 로고    scopus 로고
    • Automated quantitative analysis of angiogenesis in the rat aorta model using Image-Pro Plus 4.1
    • DOI 10.1016/j.cmpb.2003.11.001, PII S016926070300138X
    • R.J. Blatt, A.N. Clark, J. Courtney, C. Tully, and A.L. Tucker Automated quantitative analysis of angiogenesis in the rat aorta model using Image-Pro Plus 4.1 Comput. Methods Programs Biomed. 75 1 2004 75 79 (Pubitemid 38648880)
    • (2004) Computer Methods and Programs in Biomedicine , vol.75 , Issue.1 , pp. 75-79
    • Blatt, R.J.1    Clark, A.N.2    Courtney, J.3    Tully, C.4    Tucker, A.L.5
  • 3
    • 0037150754 scopus 로고    scopus 로고
    • Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus
    • DOI 10.1016/S0024-3205(02)01729-0, PII S0024320502017290
    • J. Cho, Y.H. Kim, J.Y. Kong, C.H. Yang, and C.G. Park Protection of cultured rat cortical neurons from excitotoxicity by asarone, a major essential oil component in the rhizomes of Acorus gramineus Life Sci. 5 2002 591 599 (Pubitemid 34607650)
    • (2002) Life Sciences , vol.71 , Issue.5 , pp. 591-599
    • Cho, J.1    Ho Kim, Y.2    Kong, J.-Y.3    Ha Yang, C.4    Gook Park, C.5
  • 4
    • 80053409062 scopus 로고    scopus 로고
    • Prognostic significance of Beclin 1 in intrahepatic cholangiocellular carcinoma
    • L.W. Dong, Y.J. Hou, Y.X. Tan, L. Tang, Y.F. Pan, M. Wang, and H.Y. Wang Prognostic significance of Beclin 1 in intrahepatic cholangiocellular carcinoma Autophagy 10 2011 1 8
    • (2011) Autophagy , vol.10 , pp. 1-8
    • Dong, L.W.1    Hou, Y.J.2    Tan, Y.X.3    Tang, L.4    Pan, Y.F.5    Wang, M.6    Wang, H.Y.7
  • 5
    • 62749166697 scopus 로고    scopus 로고
    • Correlation of autophagy gene Beclin 1 to tumorigenesis and development of epithelial ovarian cancer
    • Z.L. Duan, Z.L. Peng, Z.H. Wang, and N.H. Yan Correlation of autophagy gene Beclin 1 to tumorigenesis and development of epithelial ovarian cancer Ai Zheng 26 3 2007 258 263
    • (2007) Ai Zheng , vol.26 , Issue.3 , pp. 258-263
    • Duan, Z.L.1    Peng, Z.L.2    Wang, Z.H.3    Yan, N.H.4
  • 6
    • 1542468871 scopus 로고    scopus 로고
    • Effects of beta-asarone on gene expression in mouse brain
    • Y.Q. Fang, L. Li, and Q.D. Wu Effects of beta-asarone on gene expression in mouse brain Zhong Yao Cai 9 2003 650 652
    • (2003) Zhong Yao Cai , vol.9 , pp. 650-652
    • Fang, Y.Q.1    Li, L.2    Wu, Q.D.3
  • 7
    • 41749105071 scopus 로고    scopus 로고
    • Effects of beta-asarone on expression of c-fos in kindling epilepsy rat brain
    • Y.Q. Fang, R.M. Fang, G.L. Fang, Y. Jiang, and S.Y. Fu Effects of beta-asarone on expression of c-fos in kindling epilepsy rat brain Zhongguo Zhong Yao Za Zhi 5 2008 534 536
    • (2008) Zhongguo Zhong Yao Za Zhi , vol.5 , pp. 534-536
    • Fang, Y.Q.1    Fang, R.M.2    Fang, G.L.3    Jiang, Y.4    Fu, S.Y.5
  • 8
    • 79955556566 scopus 로고    scopus 로고
    • The development of an immunohistochemical method to detect the autophagy-associated protein LC3-II in human tumor xenografts
    • S.V. Holt, B. Wyspianska, K.J. Randall, D. James, J.R. Foster, and R.W. Wilkinson The development of an immunohistochemical method to detect the autophagy-associated protein LC3-II in human tumor xenografts Toxicol. Pathol. 3 2011 516 523
    • (2011) Toxicol. Pathol. , vol.3 , pp. 516-523
    • Holt, S.V.1    Wyspianska, B.2    Randall, K.J.3    James, D.4    Foster, J.R.5    Wilkinson, R.W.6
  • 9
    • 77749264299 scopus 로고    scopus 로고
    • Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury
    • M. Jiang, K. Liu, J. Luo, and Z. Dong Autophagy is a renoprotective mechanism during in vitro hypoxia and in vivo ischemia-reperfusion injury Am. J. Pathol. 3 2010 1181 1192
    • (2010) Am. J. Pathol. , vol.3 , pp. 1181-1192
    • Jiang, M.1    Liu, K.2    Luo, J.3    Dong, Z.4
  • 10
    • 0035032723 scopus 로고    scopus 로고
    • Beclin-phosphatidylinositol 3-kinase complex functions at the trans-Golgi network
    • DOI 10.1093/embo-reports/kve061
    • A. Kihara, Y. Kabeya, Y. Ohsumi, and T. Yoshimori Beclin- phosphatidylinositol 3-kinase complex functions at the trans-Golgi network EMBO Rep. 2 2001 330 335 (Pubitemid 32401529)
    • (2001) EMBO Reports , vol.2 , Issue.4 , pp. 330-335
    • Kihara, A.1    Kabeya, Y.2    Ohsumi, Y.3    Yoshimori, T.4
  • 11
    • 25444440875 scopus 로고    scopus 로고
    • The role of autophagy in cancer development and response to therapy
    • DOI 10.1038/nrc1692, PII N1692
    • Y. Kondo, T. Kanzawa, R. Sawaya, and S. Kondo The role of autophagy in cancer development and response to therapy Nat. Rev. Cancer 5 2005 726 734 (Pubitemid 41486365)
    • (2005) Nature Reviews Cancer , vol.5 , Issue.9 , pp. 726-734
    • Kondo, Y.1    Kanzawa, T.2    Sawaya, R.3    Kondo, S.4
  • 13
    • 12944308330 scopus 로고    scopus 로고
    • Eating oneself and uninvited guests: Autophagy-related pathways in cellular defense
    • DOI 10.1016/j.cell.2005.01.005, PII S0092867405000437
    • B. Levine Eating oneself and uninvited guests: autophagy-related pathways in cellular defense Cell 120 2005 159 162 (Pubitemid 40174758)
    • (2005) Cell , vol.120 , Issue.2 , pp. 159-162
    • Levine, B.1
  • 14
    • 84862807629 scopus 로고    scopus 로고
    • The correlation between Beclin 1, p53 and themalignancy, efficacy and prognosis of lung cancer
    • X. Li, and G. Wang The correlation between Beclin 1, p53 and themalignancy, efficacy and prognosis of lung cancer Chin. J. Microbiol. 22 8 2010 714 718
    • (2010) Chin. J. Microbiol. , vol.22 , Issue.8 , pp. 714-718
    • Li, X.1    Wang, G.2
  • 15
    • 77952322271 scopus 로고    scopus 로고
    • Beta-asarone protection against beta-amyloid-induced neurotoxicity in PC12 cells via JNK signaling and modulation of Bcl-2 family proteins
    • C. Li, G. Xing, M. Dong, L. Zhou, J. Li, G. Wang, D. Zou, R. Wang, J. Liu, and Y. Niu Beta-asarone protection against beta-amyloid-induced neurotoxicity in PC12 cells via JNK signaling and modulation of Bcl-2 family proteins Eur. J. Pharmacol. 1-3 2010 96 102
    • (2010) Eur. J. Pharmacol. , vol.1-3 , pp. 96-102
    • Li, C.1    Xing, G.2    Dong, M.3    Zhou, L.4    Li, J.5    Wang, G.6    Zou, D.7    Wang, R.8    Liu, J.9    Niu, Y.10
  • 16
    • 0000906170 scopus 로고    scopus 로고
    • Induction of autophagy and inhibition of tumorigenesis by beclin 1
    • X.H. Liang, S. Jackson, M. Seaman, K. Brown, B. Kempkes, H. Hibshoosh, and B. Levine Induction of autophagy and inhibition of tumorigenesis by beclin 1 Nature 402 1999 672 676 (Pubitemid 129516338)
    • (1999) Nature , vol.402 , Issue.6762 , pp. 672-676
    • Liang, X.H.1    Jackson, S.2    Seaman, M.3    Brown, K.4    Kempkes, B.5    Hibshoosh, H.6    Levine, B.7
  • 17
    • 0027501851 scopus 로고
    • Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats
    • M.D. Linnik, R.H. Zobrist, and M.D. Hatfield Evidence supporting a role for programmed cell death in focal cerebral ischemia in rats Stroke 12 1993 2002 2008
    • (1993) Stroke , vol.12 , pp. 2002-2008
    • Linnik, M.D.1    Zobrist, R.H.2    Hatfield, M.D.3
  • 18
    • 79957648221 scopus 로고    scopus 로고
    • Analysis of the distribution of β-asarone in rat hippocampus, brainstem, cortex and cerebellum with GC-MS
    • L. Liu, and Y.Q. Fang Analysis of the distribution of β-asarone in rat hippocampus, brainstem, cortex and cerebellum with GC-MS J. Med. Plants Res. 9 2011 1728 1734
    • (2011) J. Med. Plants Res. , vol.9 , pp. 1728-1734
    • Liu, L.1    Fang, Y.Q.2
  • 20
    • 0024494427 scopus 로고
    • Reversible middle cerebral artery occlusion without craniectomy in rats
    • E.Z. Longa, P.R. Weinstein, S. Carlson, and R. Cummins Reversible middle cerebral artery occlusion without craniectomy in rats Stroke 20 1989 84 89
    • (1989) Stroke , vol.20 , pp. 84-89
    • Longa, E.Z.1    Weinstein, P.R.2    Carlson, S.3    Cummins, R.4
  • 21
    • 12944303650 scopus 로고    scopus 로고
    • Growth factor regulation of autophagy and cell survival in the absence of apoptosis
    • DOI 10.1016/j.cell.2004.11.046, PII S009286740401150X
    • J.J. Lum, D.E. Bauer, M. Kong, M.H. Harris, C. Li, T. Lindsten, and C.B. Thompson Growth factor regulation of autophagy and cell survival in the absence of apoptosis Cell 2 2005 237 248 (Pubitemid 40174766)
    • (2005) Cell , vol.120 , Issue.2 , pp. 237-248
    • Lum, J.J.1    Bauer, D.E.2    Kong, M.3    Harris, M.H.4    Li, C.5    Lindsten, T.6    Thompson, C.B.7
  • 23
    • 33947426526 scopus 로고    scopus 로고
    • The CASBAH: A searchable database of caspase substrates
    • DOI 10.1038/sj.cdd.4402103, PII 4402103
    • A.U. Luthi, and S.J. Martin The CASBAH: a searchable database of caspase substrates Cell Death Differ. 14 2007 641 650 (Pubitemid 46444502)
    • (2007) Cell Death and Differentiation , vol.14 , Issue.4 , pp. 641-650
    • Luthi, A.U.1    Martin, S.J.2
  • 27
    • 25144457455 scopus 로고    scopus 로고
    • Bcl-2 antiapoptotic proteins inhibit Beclin 1-dependent autophagy
    • DOI 10.1016/j.cell.2005.07.002, PII S0092867405006926
    • S. Pattingre, A. Tassa, X. Qu, R. Garuti, X.H. Liang, N. Mizushima, M. Packer, M.D. Schneider, and B. Levine Bcl-2 antiapoptotic proteins inhibit beclin 1-dependent autophagy Cell 122 2005 927 939 (Pubitemid 41345209)
    • (2005) Cell , vol.122 , Issue.6 , pp. 927-939
    • Pattingre, S.1    Tassa, A.2    Qu, X.3    Garuti, R.4    Xiao, H.L.5    Mizushima, N.6    Packer, M.7    Schneider, M.D.8    Levine, B.9
  • 30
    • 0034520466 scopus 로고    scopus 로고
    • Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells
    • DOI 10.1038/sj.cdd.4400759
    • K. Saeki, A. You, E. Okuma, Y. Yazaki, S.A. Susin, G. Kroemer, and F. Takaku Bcl-2 down-regulation causes autophagy in a caspase-independent manner in human leukemic HL60 cells Cell Death Differ. 7 2000 1263 1269 (Pubitemid 32042234)
    • (2000) Cell Death and Differentiation , vol.7 , Issue.12 , pp. 1263-1269
    • Saeki, K.1    Yuo, A.2    Okuma, E.3    Yazaki, Y.4    Susin, S.A.5    Kroemer, G.6    Takaku, F.7
  • 31
    • 0032501198 scopus 로고    scopus 로고
    • Estrogen attenuates over-expression of β-amyloid precursor protein messager RNA in an animal model of focal ischemia
    • DOI 10.1016/S0006-8993(98)00888-9, PII S0006899398008889
    • J. Shi, K.S. Panickar, S.H. Yang, O. Rabbani, A.L. Day, and J.W. Simpkins Estrogen attenuates over-expression of beta-amyloid precursor protein messager RNA in an animal model of focal ischemia Brain Res. 2 1998 87 92 (Pubitemid 29003393)
    • (1998) Brain Research , vol.810 , Issue.1-2 , pp. 87-92
    • Shi, J.1    Panickar, K.S.2    Yang, S.-H.3    Rabbani, O.4    Day, A.L.5    Simpkins, J.W.6
  • 33
    • 27644514227 scopus 로고    scopus 로고
    • Another way to die: Autophagic programmed cell death
    • DOI 10.1038/sj.cdd.4401777, PII 4401777
    • Y. Tsujimoto, and S. Shimizu Another way to die: autophagic programmed cell death Cell Death Differ. 12 2005 1528 1534 (Pubitemid 41553989)
    • (2005) Cell Death and Differentiation , vol.12 , Issue.SUPPL. 2 , pp. 1528-1534
    • Tsujimoto, Y.1    Shimizu, S.2
  • 34
    • 77953132491 scopus 로고    scopus 로고
    • Hyperbaric oxygen preconditioning reduces ischemia-reperfusion injury by stimulating autophagy in neurocyte
    • Y.C. Wang, S. Zhang, T.Y. Du, B. Wang, and X.Q. Sun Hyperbaric oxygen preconditioning reduces ischemia-reperfusion injury by stimulating autophagy in neurocyte Brain Res. 1323 2010 149 151
    • (2010) Brain Res. , vol.1323 , pp. 149-151
    • Wang, Y.C.1    Zhang, S.2    Du, T.Y.3    Wang, B.4    Sun, X.Q.5
  • 35
    • 79953221421 scopus 로고    scopus 로고
    • Severe global cerebral ischemia-induced programmed necrosis of hippocampal CA1 neurons in rat is prevented by 3-methyladenine: A widely used inhibitor of autophagy
    • J.Y. Wang, Q. Xia, K.T. Chu, J. Pan, L.N. Sun, B. Zeng, Y.J. Zhu, Q. Wang, K. Wang, and B.Y. Luo Severe global cerebral ischemia-induced programmed necrosis of hippocampal CA1 neurons in rat is prevented by 3-methyladenine: a widely used inhibitor of autophagy J. Neuropathol. Exp. Neurol. 4 2011 314 322
    • (2011) J. Neuropathol. Exp. Neurol. , vol.4 , pp. 314-322
    • Wang, J.Y.1    Xia, Q.2    Chu, K.T.3    Pan, J.4    Sun, L.N.5    Zeng, B.6    Zhu, Y.J.7    Wang, Q.8    Wang, K.9    Luo, B.Y.10
  • 37
    • 0031688072 scopus 로고    scopus 로고
    • Sedative and hypothermic effects induced by β-asarone, a main component of Acorus calamus
    • P. Zanoli, R. Avallone, and M. Baraldi Sedative and hypothermic effects induced by β-asarone, a main component of Acorus calamus Phytother Res. 12 1998 S114 116
    • (1998) Phytother Res. , vol.12 , pp. 114-116
    • Zanoli, P.1    Avallone, R.2    Baraldi, M.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.