Novel responsive poly(N,N-dimethylaminoethyl methacrylate) gel beads: Preparation, mechanical properties and pH-dependent swelling behavior

Journal of Polymer Research

Volumn 19, Issue 7, 2012, Pages

  Orakdogen, Nermin ^a  

^a ISTANBUL TECHNICAL UNIVERSITY   (Turkey)

Author keywords

Elasticity; Gel bead; PH responsive; Poly(N,N dimethylaminoethyl methacrylate); Swelling

Indexed keywords

ELASTICITY; GELS; PARAFFIN OILS; SWELLING;

EQUILIBRIUM SWELLING; GEL BEADS; PH-DEPENDENT SWELLING; PH-RESPONSIVE; POLY(N ,N-DIMETHYLAMINOETHYL METHACRYLATE); STIMULI-RESPONSIVE POLYMER; UNI-AXIAL COMPRESSION; VOLUME TRANSITIONS;

FUNCTIONAL POLYMERS;

EID: 84862765580     PISSN: 10229760     EISSN: None     Source Type: Journal    
DOI: 10.1007/s10965-012-9914-5     Document Type: Article

References (27)

1. Kost J, Horbett TA, Ratner BD, Singh M (1985) Glucose-sensitive membranes containing glucose oxidase: activity, swelling, and permeability studies. J Biomed Mater Res 19:1117-1133 (Pubitemid 16214582)
2. Yoshida R, Sakai K, Okano T, Sakurai Y (1995) Modulating the phase transition temperature and thermosensitivity in N-isopropylacrylamide copolymer gels. J Biomater Sci Polym Ed 6:585-598
3. Han IS, Han MH, Kim J, Leow S, Lee YJ, Horkay F, Magda JJ (2002) Constant-volume hydrogel osmometer: a new device concept for miniature biosensors. Biomacromolecules 3:1271-1275 (Pubitemid 35423025)
4. Van de Wetering P, Schuurmans-Nieuwenbroek NME, Hennink WE, Storm G (1999) Comparative transfection studies of human ovarian carcinoma cells in vitro, ex vivo and in vivo with poly(2-(dimethylamino)ethyl methacrylate)-based polyplexes. J Gene Med 1:156-165 (Pubitemid 129631071)
5. Wakebayashi D, Nishiyama N, Itaka K, Miyata K, Yamasaki Y, Harada A (2004) Polyion complex micelles of pdna with acetal-poly(ethylene glycol)-poly(2-(dimethylamino)ethyl methacrylate) block copolymer as the gene carrier system: physicochemical properties of micelles relevant to gene transfection efficacy. Biomacromolecules 5:2128-2136 (Pubitemid 39585264)
6. Hinrichs WLJ, Schuurmans-Nieuwenbroek NME, Van de Wetering P, Hennink WE (1999) Thermosensitive polymers as carriers for DNA delivery. J Control Release 60:249-259 (Pubitemid 29335950)
7. Cherng JY, Van de Wetering P, Talsma H, Crommelin DJA, Hennink WE (1996) Effect of size and serum proteins on trans-fection efficiency of poly ((2-dimethylamino) ethylmethacrylate)-plasmid nanoparticles. Pharm Res 13:1038-1042 (Pubitemid 26259003)
8. Siegel RA, Firestone BA (1988) pH-dependent equilibrium swelling properties of hydrophobic polyelectrolyte copolymer gels. Macromolecules 21:3254-3259
9. Yalong Z, Ling X, Min Y, Maolin Z, Jianrui W, Hongfei H (2006) Radiation synthesis of poly(dimethylaminoethyl methacrylate)-co-(diallyl dimethyl ammonium chloride) hydrogels and its application as a carrier for notoginsenoside delivery. Eur Polym J 42:2959-2967
10. Feil H, Bae YH, Feijen J, Kim SW (1992) Mutual influence of pH and temperature on the swelling of ionizable and thermosensitive hydrogels. Macromolecules 38:5528-5530 (Pubitemid 23572181)
11. Yangfeng C, Min Y (2001) Swelling kinetics and stimuli-responsiveness of poly(DMAEMA) hydrogels prepared by UV-irradiation. Radiat Phys Chem 61:65-68 (Pubitemid 32476812)
12. Han MH, Kim JW, Kim J, Ko JY, Magda JJ, Han IS (2003) Temperature-dependent transparency of poly(HPMA-co-DMA) hydrogels: effect of synthesis parameters. Polymer 44:4541-4546 (Pubitemid 36834760)
13. Peyratout CS, Dähne L (2004) Tailor-made polyelectrolyte micro-capsules: from multilayers to smart containers. Angew Chem Int Ed 43:3762-3783 (Pubitemid 39257491)
14. Zhang Y, Zha LS, Fu SK (2004) Kinetic analysis of poly (N-isopropylacrylamide-co-dimethylaminoethyl methacrylate) microgel latex formation. J Appl Polym Sci 92:839-846 (Pubitemid 38395231)
15. Gök E, Kiremitçi M, Ates IS (1994) Protein adsorption on functional hydrophilic polymer beads: role of structural properties and medium conditions. React Polym 24:41-48
16. Okay O, Gurun C (1992) Synthesis and formation mechanism of porous 2-hydroxyethyl methacrylate-ethylene glycol dimethacry-late copolymer beads. J Appl Polym Sci 46:401-410
17. Flory PJ (1953) Principles of polymer chemistry. Cornell University Press, Ithaca, NY
18. Treloar LRG (1975) The physics of rubber elasticity. University Press, Oxford
19. Hertz H (1881) Über die Berührung Fester Elastischer Körper (on the contact of elastic solids). J Reine und Angewandte Mathematik 92:156. In: Jones DE, Schott GA (eds) Miscellaneous papers H. Hertz. Macmillan, London, 1896
20. Barquins M, Shanahan MER (1997) Effect of surface cavities on static and dynamic adhesion to an elastomer. Int J Adhes Adhes 17:313-317 (Pubitemid 127391149)
21. Lu WM, Tung KL, Hung SM, Shiau JS, Hwang KJ (2001) Compression of deformable gel particles. Powder Technol 116:1-12
22. Briscoe BJ, Liu KK, Williams DR (1998) Adhesive contact deformation of a single microelastomeric sphere. J Colloid Interface Sci 200:256-264 (Pubitemid 28384253)
23. Johnson KL, Kendall K, Roberts AD (1971) Surface energy and the contact of elastic solids. Proc R Soc Lond A 324:301-313
24. Knaebel A, Rebre SR, Lequeux F (1997) Determination of the elastic modulus of superabsorbent gel beads. Polym Gels Netw 5:107-121 (Pubitemid 127452760)
25. Topuz F, Okay O (2009) Macroporous hydrogel beads of high toughness and superfast responsivity. React Funct Polym 69:273-280
26. Orakdogen N (2011) pH-responsive swelling behavior, elasticity and molecular characteristics of poly(N,N-dimethylaminoethyl methacrylate) gels at various initial monomer concentrations. Polym Bull 67:1347-1366
27. Sutani K, Kaetsu I, Uchida K, Matsubara Y (2002) Stimulus responsive drug release from polymer gel: controlled release of ionic drug from polyampholyte. Radiat Phys Chem 64:331-336 (Pubitemid 34460580)