Radiation synthesis of poly[(dimethylaminoethyl methacrylate)-co-(diallyl dimethyl ammonium chloride)] hydrogels and its application as a carrier for notoginsenoside delivery

European Polymer Journal

Volumn 42, Issue 11, 2006, Pages 2959-2967

  Zhang, Yalong ^a   Xu, Ling ^a   Yi, Min ^a   Zhai, Maolin ^a   Wang, Jianrui ^b   Ha, Hongfei ^a  

^a Peking University   (China)

^b BEIJING UNIVERSITY OF CHINESE MEDICINE   (China)

Author keywords

Chinese herb extract; Controlled release; Hydrogels; Notoginsenoside; pH Temperature stimuli response; Poly(DMAEMA co DADMAC)

Indexed keywords

CHARGE CARRIERS; COPOLYMERIZATION; COPOLYMERS; CROSSLINKING; ENERGY DISPERSIVE SPECTROSCOPY; PH EFFECTS; SYNTHESIS (CHEMICAL);

CHINESE HERB EXTRACT; CONTROLLED RELEASE; NOTOGINSENOSIDE DELIVERY; PH/TEMPERATURE STIMULI-RESPONSE; POLY(DMAEMA-CO-DADMAC);

HYDROGELS;

EID: 33750223861     PISSN: 00143057     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.eurpolymj.2006.08.008     Document Type: Article

References (32)

1. Li Q., Ye Y.Q., and Xing Q.Y. Progress on the water-soluble constituents and its pharmacology of Panax potoginsen. Chem J Chin Univ 17 (1996) 1886-1892
2. Zhang B.H. Progress on the pharmacology of Panax notoginseng. Chin Traditional Herbal Drugs 15 11 (1984) 34-38
3. Sen M., and Sari M. Radiation synthesis and characterization of poly(N,N-dimethylaminoethyl methacrylate-co-N-vinyl 2-pyrrolidone) hydrogels. Eur Polym J 41 (2005) 1304-1314
4. Van de Watering P., Schuurmans-Nieuwenbroek N.M.E., Van Steenbergen M.J., Crommelin D.J.A., and Hennink W.E. Copolymers of 2-(dimethylamino)ethyl methacrylate with ethoxytriethylene glycol methacrylate or N-vinyl-pyrrolidone as gene transfer agents. J Controlled Release 64 (2000) 193-203
5. Van de Watering P., Cherng J.Y., Talsma H., Crommelin D.J.A., and Hennink W.E. 2-(dimethylamino)ethyl methacrylate based (co)polymers as gene transfer agents. J Controlled Release 53 (1998) 145-153
6. Hinrichs W.L.J., Schuurmans-Nieuwenbroek N.M.E., Van de Wetering P., and Hennink W.E. Thermosensitive polymers as carriers for DNA delivery. J Controlled Release 60 (1999) 249-259
7. Kurisawa M., Yokoyama M., and Okano T. Gene expression control by temperature with thermo-responsive polymeric gene carriers. J Controlled Release 69 (2000) 127-137
8. Rungsardthong U., Deshpande M.C., Bailey L., Vamvakaki M., Armes S.P., Garnett M.C., et al. Copolymers of amine methacrylate with poly(ethylene glycol) as vectors for gene therapy. J Controlled Release 73 (2001) 359-380
9. Deshpande M.C., Garnett M.C., Vamvakaki M., Bailey L., Armes S.P., and Stolnik S. Influence of polymer architecture on the structure of complexes formed by PEG-tertiary amine methacrylate copolymers and phosphorothioate oligonucleotide. J Controlled Release 81 (2002) 185-199
10. Yuk S.H., Cho S.H., and Lee S.H. pH/Temperature-responsive polymer composed of poly[(N,N-dimethylamino) ethyl methacrylate-co-ethylacrylamide]. Macromolecules 30 (1997) 6856-6859
11. Traitel T., Cohen Y., and Kost J. Characterization of glucose-sensitive insulin release systems in simulated in vivo conditions. Biomaterials 21 (2000) 1679-1687
12. Basan H., Gümüşderelíoǧlu M., and Orbey T. Diclofenac sodium releasing pH-sensitive monolithic devices. Int J Pharma 245 (2002) 191-198
13. Liu N., Yi M., Zhai M.L., Li J.Q., and Ha H.F. Radiation synthesis and characterization of polyDMAEMA hydrogel. Radiat Phys Chem 61 (2001) 69-73
14. Chen Y.F., and Yi M. Swelling kinetics and stimuli-responsiveness of poly(DMAEMA) hydrogels prepared by UV-irradiation. Radiat Phys Chem 61 (2001) 65-68
15. - ions on poly-DMAEMA hydrogel prepared by UV-induced polymerization. React Funct Polym 59 2 (2004) 149-154
16. Zhai M.L., Chen Y.F., Yi M., and Ha H.F. Swelling behavior of a new kind of polyampholyte hydrogels composed of dimethylaminoethyl methacrylate and acrylic acid. Polym Int 53 1 (2004) 33-36
17. Liu Z.G., Yi M., Zhai M.L., and Ha H.F. Radiation synthesis and environmental responsiveness of semi-interpenetrating polymer networks composed of poly(dimethylaminoethyl methacrylate) and poly(ethylene oxide). J Appl Polym Sci 92 (2004) 2995-3001
18. Wandrey C., and Hunkeler D. Diallyldimethylammonium chloride and its polymer. Adv Polym Sci 145 (1999) 123-182
19. Ren J., Zhang Y.Q., Li J.Q., and Ha H.F. Radiation synthesis and characteristic of IPN hydrogels composed of poly(diallyldimethyl ammonium chloride) and kappa-carrageenan. Radiat Phys Chem 62 (2001) 277-281
20. Ren J., and Ha H.F. Study on interpenetrating polymer network hydrogel of diallyldimethylammonium chloride with kappa-carrageenan by UV irradiation. Eur Polym J 37 (2001) 2413-2417
21. Liu N., Yi M., Chen S.J., and Ha H.F. Radiation synthesis and characteristic of diallyldimethyl ammonium chloride. Chin J Polym Sci 20 5 (2002) 409-412
22. Costas C.N., and Patrickios C.S. Near-monodisperse alpha-hydroxy and alpha, omega-dihydroxy amine-based polymers: Synthesis and characterization. J Polym Sci A: Polym Chem 37 (1997) 1597-1607
23. Kriz J., and Dautzenberg J. Cooperative interactions of unlike macromolecules 2: NMR and theoretical study of electrostatic binding of sodium poly(styrenesulfonate)s to copolymers with variably distributed cationic groups. J Phys Chem A 105 (2001) 3846-3854
24. Hagiopol C. Copolymerization toward a systematic approach (1999), Plenum Publishers, Kluwer Academic, New York
25. Huang C., and Zhang L. Miscibility of poly(vinylidene fluoride) and atactic poly(methyl methacrylate). J Appl Polym Sci 92 (2004) 1-5
26. Carlmark A., and Malmstrom E.E. ATRP grafting from cellulose fibers to create block-copolymer grafts. Biomacromolecules 4 (2003) 1740-1745
27. Ali Said A.E.-H. Radiation synthesis of interpolymer polyelectrolyte complex and its application as a carrier for colon-specific drug delivery system. Biomaterials 26 (2005) 2733-2739
28. Oguz O., and Durmaz S. Charge density dependence of elastic modulus of strong polyelectrolyte hydrogels. Polymer 43 (2002) 1215-1221
29. Yasumoto N., Kasahara N., Sasaki A., and Satoh M. Ion-specific swelling behavior of partially quaternized poly(4-vinyl pyridine) gel. Colloid Polym Sci 284 8 (2006) 900-908
30. Xu F.J., Kang E.T., and Neoh K.G. pH- and temperature-responsive hydrogels from crosslinked triblock copolymers prepared via consecutive atom transfer radical polymerization. Biomaterials 27 (2006) 2787-2797
31. Feil H., Bae Y.H., Feijen J., and Kiml S.W. Effect of comonomer hydrophilicity and ionization on the lower critical solution temperature of N-isopropylacrylamide copolymers. Macromolecules 26 (1993) 2496-2500
32. Gan L.H., Roshan D.G., Loh X.J., and Gan Y.Y. New stimuli- responsive copolymers of N-acryloyl-N′-alkyl piperazine and methyl methacrylate and their hydrogels. Polymer 42 (2001) 65-69