Human ovarian cancer stem-like cells can be efficiently killed by γδ T lymphocytes

Cancer Immunology, Immunotherapy

Volumn 61, Issue 7, 2012, Pages 979-989

  Lai, Dongmei ^a   Wang, Fangyuan ^a   Chen, Yifei ^a   Wang, Chunhui ^b   Liu, Sha ^b   Lu, Bufeng ^b   Ge, Xirui ^b   Guo, Lihe ^b  

^a SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b Hehong Shanghai Biotechnology Ltd   (China)

Author keywords

T cells; Cytokine production; Immunotherapy; Ovarian cancer stem cells; Transwell coculture

Indexed keywords

HLA DR ANTIGEN; INTERLEUKIN 17;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIGEN EXPRESSION; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER IMMUNOTHERAPY; CANCER INHIBITION; CANCER STEM CELL; CELL DIFFERENTIATION; CELL MEDIATED CYTOTOXICITY; CELL PROLIFERATION; CELL STRUCTURE; CELL THERAPY; CONTROLLED STUDY; CYTOKINE PRODUCTION; FEMALE; G2 PHASE CELL CYCLE CHECKPOINT; GAMMA DELTA T LYMPHOCYTE; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; SENSITIVITY ANALYSIS; TREATMENT RESPONSE; TUMOR IMMUNITY;

ANIMALS; APOPTOSIS; CELL LINE, TUMOR; COCULTURE TECHNIQUES; FEMALE; G2 PHASE CELL CYCLE CHECKPOINTS; HLA-DR ANTIGENS; HUMANS; IMMUNOTHERAPY, ADOPTIVE; INTERLEUKIN-17; M PHASE CELL CYCLE CHECKPOINTS; MICE; MICE, INBRED BALB C; MICE, NUDE; NEOPLASMS, GLANDULAR AND EPITHELIAL; NEOPLASTIC STEM CELLS; OVARIAN NEOPLASMS; RECEPTORS, ANTIGEN, T-CELL, GAMMA-DELTA; T-LYMPHOCYTES; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84862760572     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-011-1166-4     Document Type: Article

References (33)

1. BD Rufford IJ Jacobs U Menon 2007 Feasibility of screening for ovarian cancer using symptoms as selection criteria BJOG 114 59 64 17233861 1:STN:280:DC%2BD2s%2FjsVSrug%3D%3D
2. K Croker AL Allan 2008 Cancer stem cells: implications for the progression and treatment of metastatic disease J Cell Mol Med 12 374 390 18182063 10.1111/j.1582-4934.2007.00211.x 1:CAS:528:DC%2BD1cXms1aqtbs%3D
3. SA Bapat AM Mali CB Koppikar NK Kurrey 2005 Stem and progenitor-like cells contribute to the aggressive behavior of human epithelial ovarian cancer Cancer Res 65 3025 3029 15833827 1:CAS:528:DC%2BD2MXjt1yksrk%3D
4. AB Alvero R Chen HH Fu M Montagna PE Schwartz, et al. 2009 Molecular phenotyping of human ovarian cancer stem cells unravels the mechanisms for repair and chemoresistance Cell Cycle 8 158 166 19158483 10.4161/cc.8.1.7533 1:CAS:528:DC%2BD1MXlvFSqt7s%3D
5. T Liu WW Cheng DM Lai Y Huang 2010 Characterization of primary ovarian cancer cells in different culture system Oncol Rep 23 1277 1284 20372841 10.3892/or-00000730 1:CAS:528:DC%2BC3cXmsVKhsLw%3D
6. Ma L, Lai DM, Liu T, Cheng WW, Guo LH (2010) Cancer stem-like cells can be isolated with drug selection in human ovarian cancer cell line SK-OV-3. Acta Biochim Biophys Sin 42:593-602
7. RA Lake BW Robinson 2005 Immunotherapy and chemotherapy: a practical partnership Nat Rev Cancer 5 397 405 15864281 10.1038/nrc1613 1:CAS:528:DC%2BD2MXjslertbk%3D
8. Galon JA, Costes F, Sanchez-Cabo A, Kirilovsky B, Mlecnik Lagorce-Pages M et al Type, density, and location of immune cells within human colorectal tumors predict clinical outcome. Science 313:1960-1964
9. L Gattinoni DJ Powell SA Rosenberg NP Restifo 2006 Adoptive immunotherapy for cancer: building on success Nat Rev Immunol 6 383 393 16622476 10.1038/nri1842 1:CAS:528:DC%2BD28XjslOgsrw%3D
10. MJ Smyth GP Dunn RD Schreiber 2006 Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity Adv Immunol 90 1 50 16730260 10.1016/S0065-2776(06) 90001-7 1:CAS:528:DC%2BD1cXhsVCjtbc%3D
11. G Peng HY Wang W Peng Y Kiniwa KH Seo, et al. 2007 Tumor-infiltrating gammadelta T cells suppress T and dendritic cell function via mechanisms controlled by a unique Toll-like receptor signaling pathway Immunity 27 334 348 17656116 10.1016/j.immuni.2007.05.020 1:CAS:528:DC%2BD2sXhtVSgtb3F
12. Y Gao W Yang M Pan E Scully M Girardi, et al. 2003 Gamma delta T cells provide an early source of interferon gamma in tumor immunity J Exp Med 198 433 442 12900519 10.1084/jem.20030584 1:CAS:528:DC%2BD3sXmt1Ggsr8%3D
13. W He J Hao S Dong Y Gao J Tao, et al. 2010 Naturally activated Vgamma4 gammadelta T cells play a protective role in tumor immunity through expression of eomesodermin J Immunol 185 126 133 20525896 10.4049/jimmunol.0903767 1:CAS:528:DC%2BC3cXns1Crurg%3D
14. Y Tanaka S Sano E Nieves G De Libero D Rosa, et al. 1994 Nonpeptide ligands for human gamma delta T cells Proc Natl Acad Sci USA 91 17 8175 8179 8058775 10.1073/pnas.91.17.8175 1:CAS:528:DyaK2cXlsFGitrY%3D
15. SH Chen A Oki S Ishikawa T Ohno M Mochizuki, et al. 1996 Selective proliferation of human γδ T cells in vitro Cell Res 6 2 177 187 10.1038/cr.1996.19
16. H Dolstra H Fredrix A van der Meer T de Witte C Figdor, et al. 2001 TCR gamma delta cytotoxic T lymphocytes expressing the killer cell-inhibitory receptor p58.2 (CD158b) selectively lyse acute myeloid leukemia cells Bone Marrow Transpl 27 1087 1093 10.1038/sj.bmt.1703043 1:STN:280: DC%2BD3MznvFOhsA%3D%3D
17. S Rothenfusser A Buchwald S Kock S Ferrone P Fisch 2002 Missing HLA class I expression on Daudi cells unveils cytotoxic and proliferative responses of human gammadelta T lymphocytes Cell Immunol 215 32 44 12142034 10.1016/S0008-8749(02)00001-1 1:CAS:528:DC%2BD38XlsFKnsrg%3D
18. M Campoli S Ferrone 2008 HLA antigen changes in malignant cells: epigenetic mechanisms and biologic significance Oncogene 27 5869 5885 18836468 10.1038/onc.2008.273 1:CAS:528:DC%2BD1cXhtF2msbnF
19. A Takeuchi T Dejima H Yamada K Shibata R Nakamura, et al. 2011 IL-17 production by γδ T cells is important for the antitumor effect of Mycobacterium bovis bacillus Calmette-Guérin treatment against bladder cancer Eur J Immunol 41 246 251 21182095 10.1002/eji.201040773 1:CAS:528:DC%2BC3cXhsF2rsrnF
20. C Hirschmann-Jax AE Foster GG Wulf JG Nuchtern TW Jax, et al. 2004 A distinct ''side population'' of cells with high drug efflux capacity in human tumor cells Proc Natl Acad Sci USA 101 14228 14233 15381773 10.1073/pnas. 0400067101 1:CAS:528:DC%2BD2cXosVyltr8%3D
21. LY Bourguignon K Peyrollier W Xia E Gilad 2008 Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells J Biol Chem 283 17635 17651 18441325 10.1074/jbc.M800109200 1:CAS:528:DC%2BD1cXntFSmsrw%3D
22. M Diehn RW Cho NA Lobo T Kalisky MJ Dorie, et al. 2009 Association of reactive oxygen species levels and radioresistance in cancer stem cells Nature 458 780 783 19194462 10.1038/nature07733 1:CAS:528:DC%2BD1MXhsVCrtbc%3D
23. Y Tanaka CT Morita E Nieves MB Brenner BR Bloom 1995 Natural and synthetic non-peptide antigens recognized by human gamma delta T cells Nature 375 155 158 7753173 10.1038/375155a0 1:CAS:528:DyaK2MXls1Wisrk%3D
24. Y Kato Y Tanaka F Miyagawa S Yamashita N Minat 2001 Targeting of tumor cells for human gammadelta T cells by nonpeptide antigens J Immunol 167 5092 5098 11673519 1:CAS:528:DC%2BD3MXotVWjs7w%3D
25. SR Mattarollo T Kenna M Nieda AJ Nicol 2007 Chemotherapy and zoledronate sensitize solid tumour cells to Vγ9 Vδ2 T cell cytotoxicity Cancer Immunol Immunother 56 1285 1297 17265022 10.1007/s00262-007-0279-2 1:CAS:528:DC%2BD2sXltlSks7k%3D
26. KS Sato H Kimura A Segawa S Yokota J Matsumoto, et al. 2005 Cytotoxic effects of gammadelta T cells expanded ex vivo by a third generation bisphos-phonate for cancer immunotherapy Int J Cancer 116 94 99 15756684 10.1002/ijc.20987 1:CAS:528:DC%2BD2MXls1Kjt7w%3D
27. E Viey G Fromont B Escudier Y Morel S Da Rocha, et al. 2005 Phosphostim-activated γδ T cells kill autologous metastatic renal cell carcinoma J Immunol 174 1338 1347 15661891 1:CAS:528:DC%2BD2MXlsFygsQ%3D%3D
28. Weng D, Song B, Durfee J, Sugiyama V, Wu Z et al (2010) Induction of cytotoxic T lymphocytes against ovarian cancer-initiating cells. Int J Cancer (Epub ahead of print)
29. M Todaro M D'Asaro N Caccamo F Iovino MG Francipane, et al. 2009 Efficient killing of human colon cancer stem cells by gammadelta T lymphocytes J Immunol 182 7287 7296 19454726 10.4049/jimmunol.0804288 1:CAS:528: DC%2BD1MXmtVKqurc%3D
30. D Kabelitz D Wesch W He 2007 Perspectives of gammadelta T cells in tumor immunology Cancer Res 67 5 8 17210676 10.1158/0008-5472.CAN-06-3069 1:CAS:528:DC%2BD2sXisFWhsg%3D%3D
31. M Bonneville E Scotet 2006 Human Vγ9 Vδ2 T cells: promising new leads for immunotherapy of infections and tumors Curr Opin Immunol 18 539 546 16870417 10.1016/j.coi.2006.07.002 1:CAS:528:DC%2BD28XpsVKqu7k%3D
32. B Martin K Hirota DJ Cua B Stockinger M Veldhoen 2009 Interleukin-17-producing gammadelta T cells selectively expand in response to pathogen products and environmental signals Immunity 31 321 330 19682928 10.1016/j.immuni.2009.06.020 1:CAS:528:DC%2BD1MXhtFOgsL%2FO
33. Zhao Q, Xiao X, Wu Y, Wei Y, Zhu LY, Zhou J, Kuang DM (2011) Interleukin-17-educated monocytes suppress cytotoxic T cell function through B7-H1 in hepatocellular carcinoma patients. Eur J Immunol (Epub ahead of print)