Effect of trans-resveratrol on the thrombogenicity and atherogenicity in apolipoprotein E-deficient and low-density lipoprotein receptor-deficient mice

Blood Coagulation and Fibrinolysis

Volumn 15, Issue 6, 2004, Pages 441-446

  Fukao, Hideharu ^a   Ijiri, Yoshinobu ^b   Miura, Mayuko ^b   Hashimoto, Masaru ^b   Yamashita, Tsutomu ^b   Fukunaga, Chizuru ^c   Oiwa, Kazuhiro ^d   Kawai, Yasuhiro ^e   Suwa, Makato ^e   Yamamoto, Junichiro ^b  

^a Kurashiki Sakuyo University   (Japan)

^b KOBE GAKUIN UNIVERSITY   (Japan)

^c Kakogawa Synth Public Health Center   (Japan)

^d NATIONAL INSTITUTE OF INFORMATION AND COMMUNICATIONS TECHNOLOGY   (Japan)

^e Sunstar Inc   (Japan)

Author keywords

Atherosclerosis; Helium neon laser; Hypercholesterolemic mice; Platelet aggregates; Resveratrol

Indexed keywords

APOLIPOPROTEIN E; CHOLESTEROL; EVANS BLUE; HELIUM; LOW DENSITY LIPOPROTEIN RECEPTOR; RESVERATROL; TRIACYLGLYCEROL;

ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTICLE; ATHEROGENESIS; ATHEROMA; COMPUTER SYSTEM; CONTROLLED STUDY; ENDOTHELIUM; HYPERCHOLESTEROLEMIA; IMAGE ANALYSIS; IRRADIATION; LASER; LIPID DIET; MALE; MORPHOMETRICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; STATISTICAL SIGNIFICANCE; THROMBOCYTE AGGREGATION; THROMBOGENESIS; THROMBOGENICITY; THROMBUS;

ANIMALS; AORTIC DISEASES; APOLIPOPROTEINS E; ARTERIOSCLEROSIS; CAROTID ARTERY THROMBOSIS; CHOLESTEROL; DIET, ATHEROGENIC; DIETARY FATS; DRUG EVALUATION, PRECLINICAL; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PLATELET AGGREGATION; RADIATION INJURIES, EXPERIMENTAL; RECEPTORS, LDL; STILBENES; THROMBOPHILIA; TRIGLYCERIDES;

EID: 4444228395     PISSN: 09575235     EISSN: None     Source Type: Journal    
DOI: 10.1097/00001721-200408000-00001     Document Type: Article

References (27)

1. Ulbricht TL, Southgate DA. Coronary heart disease: seven dietary factors. Lancet 1991; 338:985-992.
2. Renaud S, de Lorgeril M. Wine, alcohol, platelets, and the French paradox for coronary heart disease. Lancet 1992; 339:1523-1526.
3. Law M, Wald N. Why heart disease mortality is low in France: the time lag explanation. BMJ 1999; 318:471-476.
4. Fremont L. Biological effects of resveratrol. Life Sci 2000; 66:663-673.
5. Zbikowska HM, Olas B. Antioxidants with carcinostatic activity (resveratrol, vitamin E and selenium) in modulation of blood platelet adhesion. J Physiol Pharmacol 2000; 51:513-520.
6. Dobrydneva Y, Williams RL, Blackmore PF. trans-Resveratrol inhibits calcium influx in thrombin-stimulated human platelets. Br J Pharmacol 1999; 128:149-157.
7. Pace-Asciak CR, Hahn S, Diamandis EP, Soleas G, Goldberg DM. The red wine phenolics trans-resveratrol and quercetin block human platelet aggregation and eicosanoid synthesis: implications for protection against coronary heart disease. Clin Chim Acta 1995; 235:207-219.
8. Olas B, Wachowicz B. Resveratrol and vitamin C as antioxidants in blood platelets. Thromb Res 2002; 106:143-1489.
9. Brito P, Almeida LM, Dinis TC. The interaction of resveratrol with ferrylmyoglobin and peroxynitrite: protection against LDL oxidation. Free Radic Res 2002; 36:621-631.
10. Araim O, Ballantyne J, Waterhouse AL, Sumpio BE. Inhibition of vascular smooth muscle cell proliferation with red wine and red wine polyphenols. J Vasc Surg 2002; 35:1226-1232.
11. Haider UG, Sorescu D, Griendling KK, Vollmar AM, Dirsch VM. Resveratrol suppresses angiotensin II-induced Akt/protein kinase B and p70 S6 kinase phosphorylation and subsequent hypertrophy in rat aortic smooth muscle cells. Mol Pharmacol 2002; 62:772-777.
12. Belguendouz L, Fremont L, Gozzelino MT. Interaction of transresveratrol with plasma lipoproteins. Biochem Pharmacol 1998; 55:811-816.
13. Ishibashi S, Herz J, Maeda N, Goldstein JL, Brown MS. The two-receptor model of lipoprotein clearance: tests of the hypothesis in 'knockout' mice lacking the low density lipoprotein receptor, apolipoprotein E, or both proteins. Proc Natl Acad Sci USA 1994; 91:4431-4435.
14. Ijiri Y, Miura M, Hashimoto M, Fukunaga C, Watanabe S, Kubota A, et al. A new model to evaluate the diet-induced prothrombotic state, using He-Ne laser-induced thrombogenesis in the carotid artery of apolipoprotein receptor E-deficient and low-density lipoprotein receptor-deficient mice. Blood Coagul Fibrinolysis 2002; 13:497-504.
15. Richmond W. Preparation and properties of a cholesterol oxidase from Nocardia sp. and its application to the enzymatic assay of total cholesterol in serum. Clin Chem 1973; 19:1350-1356.
16. Hara I, Shiraishi K, Okazaki M. High-performance liquid chromatography of human serum lipoproteins: selective detection of triglycerides by enzymatic reaction. J Chromatogr 1982; 239:549-557.
17. Palinski W, Ord VA, Plump AS, Breslow JL, Steinberg D, Witztum JL. ApoE-deficient mice are a model of lipoprotein oxidation in atherogenesis. Demonstration of oxidation-specific epitopes in lesions and high titers of autoantibodies to malondialdehyde-lysine in serum. Arterioscler Thromb 1994; 14:605-616.
18. Bergqvist D, Arfors KE. Microvascular haemostasis and the effect of local stimulation and inhibition of platelet function. An experimental study in rabbits. Thromb Haemost 1976; 36:133-139.
19. Weichert W, Breddin HK, Staubesand J. Application of a laser-induced endothelial injury model in the screening of antithrombotic drugs. Semin Thromb Hemost 1988; 14(suppl):106-114.
20. Kovacs IB, Tigyi-Sebes A, Trombitas K, Gorog P. Evans blue: an ideal energy-absorbing material to produce intravascular microinjury by HE-NE gas laser. Microvasc Res 1975; 10:107-124.
21. Yamamoto J, Iizumi H, Hirota R, Shimonaka K, Nagamatsu Y, Horie N, et al. Effect of physical training on thrombotic tendency in rats: decrease in thrombotic tendency measured by the He-Ne laser-induced thrombus formation method. Haemostasis 1989; 19:260-265.
22. Hashimoto M, Yamashita T, Oiwa K, Watanabe S, Giddings JC, Yamamoto J. Enhancement of endogenous plasminogen activator-induced thrombolysis by argatroban and activated protein C and its control by thrombin-activable fibrinolysis inhibition, measured in an arterial thrombolysis model in vivo using rat mesenteric arterioles. Thromb Haemost 2002; 87:110-113.
23. Jialal I, Grundy SM. Effect of dietary supplementation with alpha-tocopherol on the oxidative modification of low density lipoprotein. J Lipid Res 1992; 33:899-906.
24. Bertelli AA, Giovannini L, Stradi R, Bertelli A, Tillement JP. Plasma, urine and tissue levels of trans- and cis-resveratrol (3,4′,5- trihydroxystilbene) after short-term or prolonged administration of red wine to rats. Int J Tissue React 1996; 18:67-71.
25. Pendurthi UR, Meng F, Mackman N, Rao LV. Mechanism of resveratrol-mediated suppression of tissue factor gene expression. Thromb Haemost 2002; 87:155-162.
26. Abou-Agag LH, Aikens ML, Tabengwa EM, Benza RL, Shows SR, Grenett HE, et al. Polyphyenolics increase t-PA and u-PA gene transcription in cultured human endothelial cells. Alcohol Clin Exp Res 2001; 25:155-162.
27. Fukao H, Matsuo O. Anti-thrombotic regulation in human endothelial cells by fibrinolytic factors. Semin Thromb Hemost 2000; 26:33-38.