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Volumn 22, Issue 7, 2012, Pages 538-550

The 18 kDa translocator protein influences angiogenesis, as well as aggressiveness, adhesion, migration, and proliferation of glioblastoma cells

Author keywords

18 kDa translocator protein; adhesion; angiogenesis; glioblastoma; migration

Indexed keywords

COLLAGEN TYPE 1; COLLAGEN TYPE 4; FIBRINOGEN; FIBRONECTIN; LAMININ 1; N SEC BUTYL 1 (2 CHLOROPHENYL) N METHYL 3 ISOQUINOLINECARBOXAMIDE; PEPTIDES AND PROTEINS; SMALL INTERFERING RNA; TRANSLOCATOR PROTEIN; UNCLASSIFIED DRUG;

EID: 84862753717     PISSN: 17446872     EISSN: 17446880     Source Type: Journal    
DOI: 10.1097/FPC.0b013e3283539cdc     Document Type: Article
Times cited : (27)

References (74)
  • 1
    • 80053435892 scopus 로고    scopus 로고
    • Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain
    • Agarwal S, Sane R, Oberoi R, Ohlfest JR, Elmquist WF. Delivery of molecularly targeted therapy to malignant glioma, a disease of the whole brain. Expert Rev Mol Med 2011; 13:e17.
    • (2011) Expert Rev Mol Med , vol.13
    • Agarwal, S.1    Sane, R.2    Oberoi, R.3    Ohlfest, J.R.4    Elmquist, W.F.5
  • 2
    • 80053513676 scopus 로고    scopus 로고
    • Angiogenesis in glioblastoma multiforme: Navigating the maze
    • Linkous AG, Yazlovitskaya EM. Angiogenesis in glioblastoma multiforme: navigating the maze. Anticancer Agents Med Chem 2011; 11:712-718.
    • (2011) Anticancer Agents Med Chem , vol.11 , pp. 712-718
    • Linkous, A.G.1    Yazlovitskaya, E.M.2
  • 3
    • 0027051943 scopus 로고
    • 3 (peripheral-type benzodiazepine) binding site densities in different types of human brain tumours
    • DOI 10.1007/BF01541799
    • Cornu P, Benavides J, Scatton B, Hauw JJ, Philippon J. Increase in omega 3 (peripheral-type benzodiazepine) binding site densities in different types of human brain tumours. A quantitative autoradiography study. Acta Neurochir (Wien) 1992; 119:146-152. (Pubitemid 23022785)
    • (1992) Acta Neurochirurgica , vol.119 , Issue.1-4 , pp. 146-152
    • Cornu, P.1    Benavides, J.2    Scatton, B.3    Hauw, J.-J.4    Philippon, J.5
  • 6
    • 33646427447 scopus 로고    scopus 로고
    • The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development
    • Veenman L, Gavish M. The peripheral-type benzodiazepine receptor and the cardiovascular system. Implications for drug development. Pharmacol Ther 2006; 110:503-524.
    • (2006) Pharmacol Ther , vol.110 , pp. 503-524
    • Veenman, L.1    Gavish, M.2
  • 7
    • 0020002071 scopus 로고
    • 3H]Ro5-4864 benzodiazepine binding to the kainite lesioned striatum and Huntington's diseased basal ganglia
    • DOI 10.1016/0006-8993(82)90602-3
    • Schoemaker H, Morelli M, Deshmukh P, Yamamura HI. [3H]Ro5-4864 benzodiazepine binding in the kainate lesioned striatum and Huntington's diseased basal ganglia. Brain Res 1982; 248:396-401. (Pubitemid 12024439)
    • (1982) Brain Research , vol.248 , Issue.2 , pp. 396-401
    • Schoemaker, H.1    Morelli, M.2    Deshmukh, P.3    Yamamura, H.I.4
  • 8
    • 0028814911 scopus 로고
    • Ontogeny of peripheral-type benzodiazepine receptors in cultured astrocytes and brain from rat
    • Itzhak Y, Roig-Cantisano A, Norenberg MD. Ontogeny of peripheral-type benzodiazepine receptors in cultured astrocytes and brain from rat. Brain Res Dev Brain Res 1995; 84:62-66.
    • (1995) Brain Res Dev Brain Res , vol.84 , pp. 62-66
    • Itzhak, Y.1    Roig-Cantisano, A.2    Norenberg, M.D.3
  • 9
    • 0018347895 scopus 로고
    • Characterization of benzodiazepine binding sites in cultured cells of neural origin
    • Syapin PJ, Skolnick P. Characterization of benzodiazepine binding sites in cultured cells of neural origin. J Neurochem 1979; 32:1047-1051. (Pubitemid 9133265)
    • (1979) Journal of Neurochemistry , vol.32 , Issue.3 , pp. 1047-1051
    • Syapin, P.J.1    Skolnick, P.2
  • 10
    • 52449091083 scopus 로고    scopus 로고
    • Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine
    • Kugler W, Veenman L, Shandalov Y, Leschiner S, Spanier I, Lakomek M, et al. Ligands of the mitochondrial 18 kDa translocator protein attenuate apoptosis of human glioblastoma cells exposed to erucylphosphohomocholine. Cell Oncol 2008; 30:435-450.
    • (2008) Cell Oncol , vol.30 , pp. 435-450
    • Kugler, W.1    Veenman, L.2    Shandalov, Y.3    Leschiner, S.4    Spanier, I.5    Lakomek, M.6
  • 11
    • 77954590068 scopus 로고    scopus 로고
    • Potential involvement of F0F1-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines: A mechanism for induction of apoptosis via the 18 kDa mitochondrial translocator protein
    • Veenman L, Alten J, Linnemannstons K, Shandalov Y, Zeno S, Lakomek M, et al. Potential involvement of F0F1-ATP(synth)ase and reactive oxygen species in apoptosis induction by the antineoplastic agent erucylphosphohomocholine in glioblastoma cell lines: a mechanism for induction of apoptosis via the 18 kDa mitochondrial translocator protein. Apoptosis 2010; 15:753-768.
    • (2010) Apoptosis , vol.15 , pp. 753-768
    • Veenman, L.1    Alten, J.2    Linnemannstons, K.3    Shandalov, Y.4    Zeno, S.5    Lakomek, M.6
  • 12
    • 34548238745 scopus 로고    scopus 로고
    • Channel-like functions of the 18-kDA translocator protein (TSPO): Regulation of apoptosis and steroidogenesis as part of the host-defense response
    • DOI 10.2174/138161207781368710
    • Veenman L, Papadopoulos V, Gavish M. Channel-like functions of the 18-kDa translocator protein (TSPO): regulation of apoptosis and steroidogenesis as part of the host-defense response. Curr Pharm Des 2007; 13:2385-2405. (Pubitemid 47321571)
    • (2007) Current Pharmaceutical Design , vol.13 , Issue.23 , pp. 2385-2405
    • Veenman, L.1    Papadopoulos, V.2    Gavish, M.3
  • 13
    • 66349093925 scopus 로고    scopus 로고
    • CoCl(2) induces apoptosis via the 18 kDa translocator protein in U118MG human glioblastoma cells
    • Zeno S, Zaaroor M, Leschiner S, Veenman L, Gavish M. CoCl(2) induces apoptosis via the 18 kDa translocator protein in U118MG human glioblastoma cells. Biochemistry 2009; 48:4652-4661.
    • (2009) Biochemistry , vol.48 , pp. 4652-4661
    • Zeno, S.1    Zaaroor, M.2    Leschiner, S.3    Veenman, L.4    Gavish, M.5
  • 14
    • 52449115923 scopus 로고    scopus 로고
    • VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis
    • Veenman L, Shandalov Y, Gavish M. VDAC activation by the 18 kDa translocator protein (TSPO), implications for apoptosis. J Bioenerg Biomembr 2008; 40:199-205.
    • (2008) J Bioenerg Biomembr , vol.40 , pp. 199-205
    • Veenman, L.1    Shandalov, Y.2    Gavish, M.3
  • 15
    • 0032526746 scopus 로고    scopus 로고
    • PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection
    • DOI 10.1006/excr.1998.4084
    • Hirsch T, Decaudin D, Susin SA, Marchetti P, Larochette N, Resche-Rigon M, et al. PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection. Exp Cell Res 1998; 241:426-434. (Pubitemid 28366568)
    • (1998) Experimental Cell Research , vol.241 , Issue.2 , pp. 426-434
    • Hirsch, T.1    Decaudin, D.2    Susin, S.A.3    Marchetti, P.4    Larochette, N.5    Resche-Rigon, M.6    Kroemer, G.7
  • 16
    • 0028912351 scopus 로고
    • Environmentally induced changes in peripheral benzodiazepine receptors are stressor and tissue specific
    • Drugan RC, Holmes PV, Scher DM, Luczak S, Oh H, Ferland RJ. Environmentally induced changes in peripheral benzodiazepine receptors are stressor and tissue specific. Pharmacol Biochem Behav 1995; 50: 551-562.
    • (1995) Pharmacol Biochem Behav , vol.50 , pp. 551-562
    • Drugan, R.C.1    Holmes, P.V.2    Scher, D.M.3    Luczak, S.4    Oh, H.5    Ferland, R.J.6
  • 17
    • 53849125027 scopus 로고    scopus 로고
    • Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: An autoradiographic study with [(3)H]PK 11195
    • Fujimura Y, Hwang PM, Trout Iii H, Kozloff L, Imaizumi M, Innis RB, et al. Increased peripheral benzodiazepine receptors in arterial plaque of patients with atherosclerosis: an autoradiographic study with [(3)H]PK 11195. Atherosclerosis 2008; 201:108-111.
    • (2008) Atherosclerosis , vol.201 , pp. 108-111
    • Fujimura, Y.1    Hwang, P.M.2    Trout Iii, H.3    Kozloff, L.4    Imaizumi, M.5    Innis, R.B.6
  • 18
    • 77049124222 scopus 로고    scopus 로고
    • Chronic high fat, high cholesterol supplementation decreases 18 kDa Translocator Protein binding capacity in association with increased oxidative stress in rat liver and aorta
    • Dimitrova-Shumkovska J, Veenman L, Ristoski T, Leschiner S, Gavish M. Chronic high fat, high cholesterol supplementation decreases 18 kDa Translocator Protein binding capacity in association with increased oxidative stress in rat liver and aorta. Food Chem Toxicol 2010; 48:910-921.
    • (2010) Food Chem Toxicol , vol.48 , pp. 910-921
    • Dimitrova-Shumkovska, J.1    Veenman, L.2    Ristoski, T.3    Leschiner, S.4    Gavish, M.5
  • 19
    • 77956151015 scopus 로고    scopus 로고
    • Dimethylbenz[alpha]anthracene induces oxidative stress and reduces the binding capacity of the mitochondrial 18-kDa translocator protein in rat aorta
    • Dimitrova-Shumkovska J, Veenman L, Ristoski T, Leschiner S, Gavish M. Dimethylbenz[alpha]anthracene induces oxidative stress and reduces the binding capacity of the mitochondrial 18-kDa translocator protein in rat aorta. Drug Chem Toxicol 2010; 33:337-347.
    • (2010) Drug Chem Toxicol , vol.33 , pp. 337-347
    • Dimitrova-Shumkovska, J.1    Veenman, L.2    Ristoski, T.3    Leschiner, S.4    Gavish, M.5
  • 20
    • 79958262835 scopus 로고    scopus 로고
    • Differential expression of the 18 kDa translocator protein (TSPO) by neoplastic and inflammatory cells in mouse tumors of breast cancer
    • Zheng J, Boisgard R, Siquier-Pernet K, Decaudin D, Dolle F, Tavitian B. Differential expression of the 18 kDa translocator protein (TSPO) by neoplastic and inflammatory cells in mouse tumors of breast cancer. Mol Pharm 2011; 8:823-832.
    • (2011) Mol Pharm , vol.8 , pp. 823-832
    • Zheng, J.1    Boisgard, R.2    Siquier-Pernet, K.3    Decaudin, D.4    Dolle, F.5    Tavitian, B.6
  • 21
    • 38949105956 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor (PBR) new insight in cell proliferation and cell differentiation review
    • DOI 10.2174/157488408783329878
    • Corsi L, Geminiani E, Baraldi M. Peripheral benzodiazepine receptor (PBR) new insight in cell proliferation and cell differentiation review. Curr Clin Pharmacol 2008; 3:38-45. (Pubitemid 351210963)
    • (2008) Current Clinical Pharmacology , vol.3 , Issue.1 , pp. 38-45
    • Corsi, L.1    Geminiani, E.2    Baraldi, M.3
  • 22
    • 33845711642 scopus 로고    scopus 로고
    • Immunohistochemical expression of peripheral benzodiazepine receptors in human astrocytomas and its correlation with grade of malignancy, proliferation, apoptosis and survival
    • DOI 10.1007/s11060-006-9199-9
    • Vlodavsky E, Soustiel JF. Immunohistochemical expression of peripheral benzodiazepine receptors in human astrocytomas and its correlation with grade of malignancy, proliferation, apoptosis and survival. J Neurooncol 2007; 81:1-7. (Pubitemid 44963983)
    • (2007) Journal of Neuro-Oncology , vol.81 , Issue.1 , pp. 1-7
    • Vlodavsky, E.1    Soustiel, J.F.2
  • 23
    • 0033558247 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor (PBR) in human breast cancer: Correlation of breast cancer cell aggressive phenotype with PBR expression, nuclear localization, and PBR-mediated cell proliferation and nuclear transport of cholesterol
    • Hardwick M, Fertikh D, Culty M, Li H, Vidic B, Papadopoulos V. Peripheraltype benzodiazepine receptor (PBR) in human breast cancer: correlation of breast cancer cell aggressive phenotype with PBR expression, nuclear localization, and PBR-mediated cell proliferation and nuclear transport of cholesterol. Cancer Res 1999; 59:831-842. (Pubitemid 29086736)
    • (1999) Cancer Research , vol.59 , Issue.4 , pp. 831-842
    • Hardwick, M.1    Fertikh, D.2    Culty, M.3    Li, H.4    Vidic, B.5    Papadopoulos, V.6
  • 24
    • 67650550499 scopus 로고    scopus 로고
    • Chronic inflammation, the tumor microenvironment and carcinogenesis
    • Gonda TA, Tu S, Wang TC. Chronic inflammation, the tumor microenvironment and carcinogenesis. Cell Cycle 2009; 8:2005-2013.
    • (2009) Cell Cycle , vol.8 , pp. 2005-2013
    • Gonda, T.A.1    Tu, S.2    Wang, T.C.3
  • 26
    • 67651160649 scopus 로고    scopus 로고
    • CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages
    • DeNardo DG, Barreto JB, Andreu P, Vasquez L, Tawfik D, Kolhatkar N, et al. CD4(+) T cells regulate pulmonary metastasis of mammary carcinomas by enhancing protumor properties of macrophages. Cancer Cell 2009; 16: 91-102.
    • (2009) Cancer Cell , vol.16 , pp. 91-102
    • Denardo, D.G.1    Barreto, J.B.2    Andreu, P.3    Vasquez, L.4    Tawfik, D.5    Kolhatkar, N.6
  • 27
    • 33846205518 scopus 로고    scopus 로고
    • The peripheral benzodiazepine receptor (Translocator protein 18 kDa) in microglia: From pathology to imaging
    • DOI 10.1016/j.pneurobio.2006.10.002, PII S0301008206001316
    • Venneti S, Lopresti BJ, Wiley CA. The peripheral benzodiazepine receptor (translocator protein 18kDa) in microglia: from pathology to imaging. Prog Neurobiol 2006; 80:308-322. (Pubitemid 46107737)
    • (2006) Progress in Neurobiology , vol.80 , Issue.6 , pp. 308-322
    • Venneti, S.1    Lopresti, B.J.2    Wiley, C.A.3
  • 28
    • 79955752123 scopus 로고    scopus 로고
    • The translocator protein
    • Scarf AM, Kassiou M. The translocator protein. J Nucl Med 2011; 52: 677-680.
    • (2011) J Nucl Med , vol.52 , pp. 677-680
    • Scarf, A.M.1    Kassiou, M.2
  • 30
    • 56149099254 scopus 로고    scopus 로고
    • The 18-kDa translocator protein, formerly known as the peripheral-type benzodiazepine receptor, confers proapoptotic and antineoplastic effects in a human colorectal cancer cell line
    • Shoukrun R, Veenman L, Shandalov Y, Leschiner S, Spanier I, Karry R, et al. The 18-kDa translocator protein, formerly known as the peripheral-type benzodiazepine receptor, confers proapoptotic and antineoplastic effects in a human colorectal cancer cell line. Pharmacogenet Genomics 2008; 18:977-988.
    • (2008) Pharmacogenet Genomics , vol.18 , pp. 977-988
    • Shoukrun, R.1    Veenman, L.2    Shandalov, Y.3    Leschiner, S.4    Spanier, I.5    Karry, R.6
  • 31
    • 4644295513 scopus 로고    scopus 로고
    • Peripheral benzodiazepine receptor antisense knockout increases tumorigenicity of MA-10 Leydig cells in vivo and in vitro
    • DOI 10.1021/bi030251v
    • Weisinger G, Kelly-Hershkovitz E,Veenman L, Spanier I, Leschiner S, Gavish M. Peripheral benzodiazepine receptor antisense knockout increases tumorigenicity of MA-10 Leydig cells in vivo and in vitro. Biochemistry 2004; 43:12315-12321. (Pubitemid 39280575)
    • (2004) Biochemistry , vol.43 , Issue.38 , pp. 12315-12321
    • Weisinger, G.1    Kelly-Hershkovitz, E.2    Veenman, L.3    Spanier, I.4    Leschiner, S.5    Gavish, M.6
  • 32
    • 84860271665 scopus 로고    scopus 로고
    • The 18 kDa mitochondrial translocator Protein (TSPO) prevents accumulation of protoporphyrin IX. A TSPO knockdown study
    • [Epub ahead of print]
    • Zeno S, Veenman L, Katz Y, Bode J, Gavish M, Zaaroor M. The 18 kDa mitochondrial translocator Protein (TSPO) prevents accumulation of protoporphyrin IX. A TSPO knockdown study. Curr Mol Med 2012 [Epub ahead of print].
    • (2012) Curr Mol Med
    • Zeno, S.1    Veenman, L.2    Katz, Y.3    Bode, J.4    Gavish, M.5    Zaaroor, M.6
  • 33
    • 3342904989 scopus 로고    scopus 로고
    • Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-α dependent up-regulation of matrix metalloproteases
    • DOI 10.1093/carcin/bgh146
    • Hagemann T, Robinson SC, Schulz M, Trumper L, Balkwill FR, Binder C. Enhanced invasiveness of breast cancer cell lines upon co-cultivation with macrophages is due to TNF-alpha dependent up-regulation of matrix metalloproteases. Carcinogenesis 2004; 25:1543-1549. (Pubitemid 39162720)
    • (2004) Carcinogenesis , vol.25 , Issue.8 , pp. 1543-1549
    • Hagemann, T.1    Robinson, S.C.2    Schulz, M.3    Trumper, L.4    Balkwill, F.R.5    Binder, C.6
  • 34
    • 70249090440 scopus 로고    scopus 로고
    • Stanniocalcin 2 promotes invasion and is associated with metastatic stages in neuroblastoma
    • Volland S, Kugler W, Schweigerer L, Wilting J, Becker J. Stanniocalcin 2 promotes invasion and is associated with metastatic stages in neuroblastoma. Int J Cancer 2009; 125:2049-2057.
    • (2009) Int J Cancer , vol.125 , pp. 2049-2057
    • Volland, S.1    Kugler, W.2    Schweigerer, L.3    Wilting, J.4    Becker, J.5
  • 35
    • 1642504354 scopus 로고    scopus 로고
    • Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries
    • DOI 10.1038/sj.bjp.0705554
    • Erdlenbruch B, Alipour M, Fricker G, Miller DS, Kugler W, Eibl H, et al. Alkylglycerol opening of the blood-brain barrier to small and large fluorescence markers in normal and C6 glioma-bearing rats and isolated rat brain capillaries. Br J Pharmacol 2003; 140:1201-1210. (Pubitemid 38117424)
    • (2003) British Journal of Pharmacology , vol.140 , Issue.7 , pp. 1201-1210
    • Erdlenbruch, B.1    Alipour, M.2    Fricker, G.3    Miller, D.S.4    Kugler, W.5    Eibl, H.6    Lakomek, M.7
  • 36
    • 0037461325 scopus 로고    scopus 로고
    • In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: Functional significance in drug ligand and cholesterol binding
    • Delavoie F, Li H, Hardwick M, Robert J-C, Giatzakis C, Péranzi G, et al. In vivo and in vitro peripheral-type benzodiazepine receptor polymerization: functional significance in drug ligand and cholesterol binding. Biochemistry 2003; 42:4509-4519.
    • (2003) Biochemistry , vol.42 , pp. 4509-4519
    • Delavoie, F.1    Li, H.2    Hardwick, M.3    Robert, J.-C.4    Giatzakis, C.5    Péranzi, G.6
  • 37
    • 56149111067 scopus 로고    scopus 로고
    • The effect of oxygenation level on cerebral post-traumatic apoptotsis is modulated by the 18-kDa translocator protein (also known as peripheral-type benzodiazepine receptor) in a rat model of cortical contusion
    • Soustiel JF, Palzur E, Vlodavsky E, Veenman L, Gavish M. The effect of oxygenation level on cerebral post-traumatic apoptotsis is modulated by the 18-kDa translocator protein (also known as peripheral-type benzodiazepine receptor) in a rat model of cortical contusion. Neuropathol Appl Neurobiol 2008; 34:412-423.
    • (2008) Neuropathol Appl Neurobiol , vol.34 , pp. 412-423
    • Soustiel, J.F.1    Palzur, E.2    Vlodavsky, E.3    Veenman, L.4    Gavish, M.5
  • 38
    • 84857047635 scopus 로고    scopus 로고
    • In vitro mitochondrial effects of PK, 11195, a synthetic translocator protein 18 kDa (TSPO) ligand, in human osteoblast-like cells
    • Rosenberg N, Rosenberg O, Weizman A, Leschiner S, Sakoury Y, Fares F, et al. In vitro mitochondrial effects of PK 11195, a synthetic translocator protein 18 kDa (TSPO) ligand, in human osteoblast-like cells. J Bioenerg Biomembr 2011; 43:739-746.
    • (2011) J Bioenerg Biomembr , vol.43 , pp. 739-746
    • Rosenberg, N.1    Rosenberg, O.2    Weizman, A.3    Leschiner, S.4    Sakoury, Y.5    Fares, F.6
  • 39
    • 84862775581 scopus 로고    scopus 로고
    • Study on cancer-cell invasion based on the diffuse interface model
    • Linan Z, Song J, Kim DA. Study on cancer-cell invasion based on the diffuse interface model. World Acad Sci Eng Technol 2010; 68:790-793.
    • (2010) World Acad Sci Eng Technol , vol.68 , pp. 790-793
    • Linan, Z.1    Song, J.2    Kim, D.A.3
  • 41
    • 37249030836 scopus 로고    scopus 로고
    • Reorganisation of the dendritic actin network during cancer cell migration and invasion
    • DOI 10.1016/j.semcancer.2007.08.001, PII S1044579X07000715
    • Vignjevic D, Montagnac G. Reorganisation of the dendritic actin network during cancer cell migration and invasion. Semin Cancer Biol 2008; 18: 12-22. (Pubitemid 350266367)
    • (2008) Seminars in Cancer Biology , vol.18 , Issue.1 , pp. 12-22
    • Vignjevic, D.1    Montagnac, G.2
  • 43
    • 0035827919 scopus 로고    scopus 로고
    • Identification of tumor suppressor candidate genes by physical and sequence mapping of the TSLC1 region of human chromosome 11q23
    • DOI 10.1016/S0378-1119(01)00592-3, PII S0378111901005923
    • Pletcher MT, Nobukuni T, Fukuhara H, Kuramochi M, Maruyama T, Sekiya T, et al. Identification of tumor suppressor candidate genes by physical and sequence mapping of the TSLC1 region of human chromosome 11q23. Gene 2001; 273:181-189. (Pubitemid 32786911)
    • (2001) Gene , vol.273 , Issue.2 , pp. 181-189
    • Pletcher, M.T.1    Nobukuni, T.2    Fukuhara, H.3    Kuramochi, M.4    Maruyama, T.5    Sekiya, T.6    Sussan, T.7    Isomura, M.8    Murakami, Y.9    Reeves, R.H.10
  • 44
    • 0027989375 scopus 로고
    • Determinants of human astrocytoma migration
    • Giese A, Rief MD, Loo MA, Berens ME. Determinants of human astrocytoma migration. Cancer Res 1994; 54:3897-3904. (Pubitemid 24241213)
    • (1994) Cancer Research , vol.54 , Issue.14 , pp. 3897-3904
    • Giese, A.1    Rief, M.D.2    Loo, M.A.3    Berens, M.E.4
  • 46
    • 0021848575 scopus 로고
    • Benzodiazepine receptor-mediated chemotaxis of human monocytes
    • Ruff MR, Pert CB,Weber RJ,Wahl LM,Wahl SM, Paul SM. Benzodiazepine receptor-mediated chemotaxis of human monocytes. Science 1985; 229:1281-1283. (Pubitemid 15021682)
    • (1985) Science , vol.229 , Issue.4719 , pp. 1281-1283
    • Ruff, M.R.1    Pert, C.B.2    Weber, R.J.3
  • 47
    • 0025990485 scopus 로고
    • Benzodiazepines inhibit neutrophil chemotaxis and superoxide production in a stimulus dependent manner; PK-11195 antagonizes these effects
    • Finnerty M, Marczynski TJ, Amirault HJ, Urbancic M, Andersen BR. Benzodiazepines inhibit neutrophil chemotaxis and superoxide production in a stimulus dependent manner; PK-11195 antagonizes these effects. Immunopharmacology 1991; 22:185-193.
    • (1991) Immunopharmacology , vol.22 , pp. 185-193
    • Finnerty, M.1    Marczynski, T.J.2    Amirault, H.J.3    Urbancic, M.4    Andersen, B.R.5
  • 48
    • 0034931018 scopus 로고    scopus 로고
    • Diazepam stimulates migration and phagocytosis of human neutrophils: Possible contribution of peripheral-type benzodiazepine receptors and intracellular calcium
    • DOI 10.1159/000056111
    • Marino F, Cattaneo S, Cosentino M, Rasini E, Di Grazia L, Fietta AM, et al. Diazepam stimulates migration and phagocytosis of human neutrophils: possible contribution of peripheral-type benzodiazepine receptors and intracellular calcium. Pharmacology 2001; 63:42-49. (Pubitemid 32623460)
    • (2001) Pharmacology , vol.63 , Issue.1 , pp. 42-49
    • Marino, F.1    Cattaneo, S.2    Cosentino, M.3    Rasini, E.4    Di Grazia, L.5    Fietta, A.M.6    Lecchini, S.7    Frigo, G.8
  • 49
    • 78650234355 scopus 로고    scopus 로고
    • Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state
    • Choi J, Ifuku M, Noda M, Guilarte TR. Translocator protein (18 kDa)/peripheral benzodiazepine receptor specific ligands induce microglia functions consistent with an activated state. Glia 2011; 59:219-230.
    • (2011) Glia , vol.59 , pp. 219-230
    • Choi, J.1    Ifuku, M.2    Noda, M.3    Guilarte, T.R.4
  • 50
    • 84862760373 scopus 로고    scopus 로고
    • Effects of TSPO knockdown on glutamate receptors, transporters, and metabolism, as well as amyloid protein in glioblastoma cells, and on cell viability as affected by Abeta(1-42) and glutamate
    • in press
    • Veenman L, Bode J, Gaitner M, Caballero B, Peer L, Zeno S, et al. Effects of TSPO knockdown on glutamate receptors, transporters, and metabolism, as well as amyloid protein in glioblastoma cells, and on cell viability as affected by Abeta(1-42) and glutamate. Pharmacogenet Genomics 2012; 12. (in press)
    • (2012) Pharmacogenet Genomics , pp. 12
    • Veenman, L.1    Bode, J.2    Gaitner, M.3    Caballero, B.4    Peer, L.5    Zeno, S.6
  • 51
    • 0034637713 scopus 로고    scopus 로고
    • Location-dependent role of the human glioma cell peripheral-type benzodiazepine receptor in proliferation and steroid biosynthesis
    • DOI 10.1016/S0304-3835(00)00451-1, PII S0304383500004511
    • Brown RC, Degenhardt B, Kotoula M, Papadopoulous V. Locationdependent role of the human glioma cell peripheral-type benzodiazepine receptor in proliferation and steroid biosynthesis. Cancer Lett 2000; 156:125-132. (Pubitemid 30394669)
    • (2000) Cancer Letters , vol.156 , Issue.2 , pp. 125-132
    • Brown, R.C.1    Degenhardt, B.2    Kotoula, M.3    Papadopoulous, V.4
  • 52
    • 41449106167 scopus 로고    scopus 로고
    • Control of peripheral benzodiazepine receptor-mediated breast cancer in rats by soy protein
    • DOI 10.1002/mc.20387
    • Mukhopadhyay S, Rajaratnam V, Mukherjee S, Das SK. Control of peripheral benzodiazepine receptor-mediated breast cancer in rats by soy protein. Mol Carcinog 2008; 47:310-319. (Pubitemid 351500157)
    • (2008) Molecular Carcinogenesis , vol.47 , Issue.4 , pp. 310-319
    • Mukhopadhyay, S.1    Rajaratnam, V.2    Mukherjee, S.3    Das, S.K.4
  • 53
    • 28244459490 scopus 로고    scopus 로고
    • Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor in human leukemia cells
    • DOI 10.1158/0008-5472.CAN-05-0510
    • Furre IE, Shahzidi S, Luksiene Z, Møller MT, Borgen E, Morgan J, et al. Targeting PBR by hexaminolevulinate-mediated photodynamic therapy induces apoptosis through translocation of apoptosis-inducing factor (to the nucleus) in human leukemia cells. Cancer Res 2005; 65: 11051-11060. (Pubitemid 41713376)
    • (2005) Cancer Research , vol.65 , Issue.23 , pp. 11051-11060
    • Furre, I.E.1    Shahzidi, S.2    Luksiene, Z.3    Moller, M.T.N.4    Borgen, E.5    Morgan, J.6    Tkacz-Stachowska, K.7    Nesland, J.M.8    Peng, Q.9
  • 54
    • 32144442981 scopus 로고    scopus 로고
    • Cancer-related overexpression of the peripheral-type benzodiazepine receptor and cytostatic anticancer effects of Ginkgo biloba extract (EGb 761)
    • Pretner E, Amri H, Li W, Brown R, Lin CS, Makariou E, et al. Cancer-related overexpression of the peripheral-type benzodiazepine receptor and cytostatic anticancer effects of Ginkgo biloba extract (EGb 761). Anticancer Res 2006; 26:9-22. (Pubitemid 43206054)
    • (2006) Anticancer Research , vol.26 , Issue.1 , pp. 9-22
    • Pretner, E.1    Amri, H.2    Li, W.3    Brown, R.4    Lin, C.-S.5    Makariou, E.6    Defeudis, F.V.7    Drieu, K.8    Papadopoulos, V.9
  • 55
    • 0034008139 scopus 로고    scopus 로고
    • TspO of Rhodobacter sphaeroides. A structural and functional model for the mammalian peripheral benzodiazepine receptor
    • DOI 10.1074/jbc.275.8.5657
    • Yeliseev AA, Kaplan S. TspO of Rhodobacter sphaeroides. A structural and functional model for the mammalian peripheral benzodiazepine receptor. J Biol Chem 2000; 275:5657-5667. (Pubitemid 30115205)
    • (2000) Journal of Biological Chemistry , vol.275 , Issue.8 , pp. 5657-5667
    • Yeliseev, A.A.1    Kaplan, S.2
  • 57
    • 33847039156 scopus 로고    scopus 로고
    • Is there a mitochondrial signaling complex facilitating cholesterol import?
    • DOI 10.1016/j.mce.2006.12.004, PII S0303720706005594, Adrenal/Molecular Steroidogenesis Conference 2006 AMS 2006
    • Papadopoulos V, Liu J, Culty M. Is there a mitochondrial signaling complex facilitating cholesterol import? Mol Cell Endocrinol 2007; 265-266:59-64. (Pubitemid 46273951)
    • (2007) Molecular and Cellular Endocrinology , vol.265-266 , Issue.SUPPL. , pp. 59-64
    • Papadopoulos, V.1    Liu, J.2    Culty, M.3
  • 58
    • 84862769433 scopus 로고    scopus 로고
    • The role of 18 kDa mitochondrial translocator protein (TSPO) in programmed cell death, and effects of steroids on TSPO expression
    • Veenman L, Gavish M. The role of 18 kDa mitochondrial translocator protein (TSPO) in programmed cell death, and effects of steroids on TSPO expression. Curr Mol Med 2011; 52:1265-1277.
    • (2011) Curr Mol Med , vol.52 , pp. 1265-1277
    • Veenman, L.1    Gavish, M.2
  • 60
    • 0033844870 scopus 로고    scopus 로고
    • Diazepam-binding inhibitor-derived peptides induce intracellular calcium changes and modulate human neutrophil function
    • Cosentino M, Marino F, Cattaneo S, Di Grazia L, Francioli C, Fietta AM, et al. Diazepam-binding inhibitor-derived peptides induce intracellular calcium changes and modulate human neutrophil function. J Leukoc Biol 2000; 67:637-643.
    • (2000) J Leukoc Biol , vol.67 , pp. 637-643
    • Cosentino, M.1    Marino, F.2    Cattaneo, S.3    Di Grazia, L.4    Francioli, C.5    Fietta, A.M.6
  • 61
    • 0034890338 scopus 로고    scopus 로고
    • The triakontatetraneuropeptide TTN increases [CA2+] in rat astrocytes through activation of peripheral-type benzodiazepine receptors
    • Gandolfo P, Louiset E, Patte C, Leprince J, Masmoudi O, Malagon M, et al. The triakontatetraneuropeptide TTN increases [CA2+] in rat astrocytes through activation of peripheral-type benzodiazepine receptors. Glia 2001; 35:90-100.
    • (2001) Glia , vol.35 , pp. 90-100
    • Gandolfo, P.1    Louiset, E.2    Patte, C.3    Leprince, J.4    Masmoudi, O.5    Malagon, M.6
  • 62
    • 0037400607 scopus 로고    scopus 로고
    • Interleukin-8 production induced by the endozepine triakontatetraneuropeptide in human neutrophils: Role of calcium and pharmacological investigation of signal transduction pathways
    • DOI 10.1016/S0898-6568(02)00134-1
    • Marino F, Cosentino M, Fietta AM, Ferrari M, Cattaneo S, Frigo G, et al. Interleukin-8 production induced by the endozepine triakontatetraneuropeptide in human neutrophils: role of calcium and pharmacological investigation of signal transduction pathways. Cell Signal 2003; 15:511-517. (Pubitemid 36287672)
    • (2003) Cellular Signalling , vol.15 , Issue.5 , pp. 511-517
    • Marino, F.1    Cosentino, M.2    Fietta, A.M.3    Ferrari, M.4    Cattaneo, S.5    Frigo, G.6    Lecchini, S.7    Frigo, G.M.8
  • 63
    • 54849403300 scopus 로고    scopus 로고
    • PK 11195 differentially affects cell survival in human wild-type and 18 kDa translocator protein-silenced ADF astrocytoma cells
    • Chelli B, Salvetti A, Da Pozzo E, Rechichi M, Spinetti F, Rossi L, et al. PK 11195 differentially affects cell survival in human wild-type and 18 kDa translocator protein-silenced ADF astrocytoma cells. J Cell Biochem 2008; 105:712-723.
    • (2008) J Cell Biochem , vol.105 , pp. 712-723
    • Chelli, B.1    Salvetti, A.2    Da Pozzo, E.3    Rechichi, M.4    Spinetti, F.5    Rossi, L.6
  • 64
    • 47949111469 scopus 로고    scopus 로고
    • The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl- methylpropyl)-3-isoquinoline-carboxamide is a novel antagonist of human constitutive androstane receptor
    • Li L, Chen T, Stanton JD, Sueyoshi T, Negishi M, Wang H. The peripheral benzodiazepine receptor ligand 1-(2-chlorophenyl-methylpropyl)-3-isoquinoline- carboxamide is a novel antagonist of human constitutive androstane receptor. Mol Pharmacol 2008; 74:443-453.
    • (2008) Mol Pharmacol , vol.74 , pp. 443-453
    • Li, L.1    Chen, T.2    Stanton, J.D.3    Sueyoshi, T.4    Negishi, M.5    Wang, H.6
  • 65
    • 33845929203 scopus 로고    scopus 로고
    • Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation
    • DOI 10.1016/j.bcp.2006.10.025, PII S0006295206006770
    • Li W, Hardwick MJ, Rosenthal D, Culty M, Papadopoulos V. Peripheral-type benzodiazepine receptor overexpression and knockdown in human breast cancer cells indicate its prominent role in tumor cell proliferation. Biochem Pharmacol 2007; 73:491-503. (Pubitemid 46038854)
    • (2007) Biochemical Pharmacology , vol.73 , Issue.4 , pp. 491-503
    • Li, W.1    Hardwick, M.J.2    Rosenthal, D.3    Culty, M.4    Papadopoulos, V.5
  • 67
    • 35348973583 scopus 로고    scopus 로고
    • Downregulation of the 18-kDa translocator protein: Effects on the ammonia-induced mitochondrial permeability transition and cell swelling in cultured astrocytes
    • DOI 10.1002/glia.20584
    • Panickar KS, Jayakumar AR, Rama Rao KV, Norenberg MD. Downregulation of the 18-kDa translocator protein: effects on the ammonia-induced mitochondrial permeability transition and cell swelling in cultured astrocytes. Glia 2007; 55:1720-1727. (Pubitemid 47612858)
    • (2007) GLIA , vol.55 , Issue.16 , pp. 1720-1727
    • Panickar, K.S.1    Jayakumar, A.R.2    Rama Rao, K.V.3    Norenberg, M.D.4
  • 68
    • 39149110569 scopus 로고    scopus 로고
    • TSPO over-expression increases motility, transmigration and proliferation properties of C6 rat glioma cells
    • Rechichi M, Salvetti A, Chelli B, Costa B, Da Pozzo E, Spinetti F, et al. TSPO over-expression increases motility, transmigration and proliferation properties of C6 rat glioma cells. Biochim Biophys Acta 2008; 1782:118-125.
    • (2008) Biochim Biophys Acta , vol.1782 , pp. 118-125
    • Rechichi, M.1    Salvetti, A.2    Chelli, B.3    Costa, B.4    Da Pozzo, E.5    Spinetti, F.6
  • 71
    • 0036639435 scopus 로고    scopus 로고
    • Modulation of tamoxifen-induced apoptosis by peripheral benzodiazepine receptor ligands in breast cancer cells
    • DOI 10.1016/S0006-2952(02)01059-6, PII S0006295202010596
    • Strohmeier R, Roller M, Sänger N, Knecht R, Kuhl H. Modulation of tamoxifen-induced apoptosis by peripheral benzodiazepine receptor ligands in breast cancer cells. Biochem Pharmacol 2002; 64:99-107. (Pubitemid 34775180)
    • (2002) Biochemical Pharmacology , vol.64 , Issue.1 , pp. 99-107
    • Strohmeier, R.1    Roller, M.2    Sanger, N.3    Knecht, R.4    Kuhl, H.5
  • 73
    • 22944465091 scopus 로고    scopus 로고
    • Resistance of human astrocytoma cells to apoptosis induced by mitochondria-damaging agents: Possible implications for anticancer therapy
    • DOI 10.1124/jpet.105.085340
    • Ceruti S, Mazzola A, Abbracchio MP. Resistance of human astrocytoma cells to apoptosis induced by mitochondria-damaging agents: possible implications for anticancer therapy. J Pharmacol Exp Ther 2005; 314: 825-837. (Pubitemid 41043868)
    • (2005) Journal of Pharmacology and Experimental Therapeutics , vol.314 , Issue.2 , pp. 825-837
    • Ceruti, S.1    Mazzola, A.2    Abbracchio, M.P.3
  • 74
    • 0025751636 scopus 로고
    • Development of an antiserum against m3 muscarinic receptors: Distribution of m3 receptors in rat tissues and clonal cell lines
    • Wall SJ, Yasuda RP, Li M, Wolfe BB. Development of an antiserum against m3 muscarinic receptors: distribution of m3 receptors in rat tissues and clonal cell lines. Mol Pharmacol 1991; 40:783-789.
    • (1991) Mol Pharmacol , vol.40 , pp. 783-789
    • Wall, S.J.1    Yasuda, R.P.2    Li, M.3    Wolfe, B.B.4


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