Synthesis of chiral tetronic acid derivatives via organocatalytic conjugate addition of ethyl 4-chloro-3-oxobutanoate to nitroalkenes

Tetrahedron

Volumn 68, Issue 31, 2012, Pages 6123-6130

  Yan, Yun Yun ^a   Lu, Rui Jiong ^a   Wang, Jin Jia ^a   Xuan, Yi Ning ^b   Yan, Ming ^a  

^a SUN YAT SEN UNIVERSITY   (China)

^b GUANGDONG PHARMACEUTICAL UNIVERSITY   (China)

Author keywords

Asymmetric conjugate addition; Ethyl 4 chloro 3 oxobutanoate; Nitroalkene; Organocatalysis; Tetronic acid derivative

Indexed keywords

5 ETHOXY 4 (1 CYCLOHEXYL 2 NITROETHYL)FURAN 3(2H) ONE; 5 ETHOXY 4 (1 NITROPROPAN 2 YL)FURAN 3(2H) ONE; 5 ETHOXY 4 (2 NITRO 1 (4 TOLYL)ETHYL)FURAN 3(2H) ONE; 5 ETHOXY 4 (2 NITRO 1 PHENYLETHYL)FURAN 3(2H) ONE; 5 ETHOXY 4 (3 METHYL 1 NITROBUTAN 2 YL)FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (2 BROMOPHENYL) 2 NITROETHYL]FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (2 CHLOROPHENYL) 2 NITROETHYL]FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (2,4 DICHLOROPHENYL) 2 NITROETHYL)FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (3 CHLOROPHENYL) 2 NITROETHYL)FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (4 BROMOPHENYL) 2 NITROETHYL]FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (4 CHLOROPHENYL) 2 NITROETHYL]FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (4 FLUOROPHENYL) 2 NITROETHYL]FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (4 METHOXYPHENYL) 2 NITROETHYL]FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (4 NITROPHENYL) 2 NITROETHYL]FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (FURAN 2 YL) 2 NITROETHYL)FURAN 3(2H) ONE; 5 ETHOXY 4 [1 (NAPHTHALEN 1 YL) 2 NITROETHYL)FURAN 3(2H) ONE; 5 ETHOXY 4 [2 NITRO 1 (2 NITROPHENYL)ETHYL]FURAN 3(2H) ONE; 5 ETHOXY 4 [2 NITRO 1 (THIOPHEN 2 YL)ETHYL]FURAN 3(2H) ONE; 6' DEMETHYL QUININE; 9 BENZYL 6' DEMETHYL QUININE; ACETOACETIC ACID; ALKENE DERIVATIVE; AMINE THIOUREA; ETHYL 4 CHLORO 3 OXOBUTANOATE; NITROALKENE DERIVATIVE; QUININE DERIVATIVE; TETRONIC ACID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CATALYST; CYCLIZATION; ENANTIOSELECTIVITY; ONE POT SYNTHESIS; PRIORITY JOURNAL; SYNTHESIS;

EID: 84862694005     PISSN: 00404020     EISSN: 14645416     Source Type: Journal    
DOI: 10.1016/j.tet.2012.05.082     Document Type: Article

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