Rapid high-amplitude circumferential slow wave propagation during normal gastric pacemaking and dysrhythmias

Neurogastroenterology and Motility

Volumn 24, Issue 7, 2012, Pages

  O'Grady, G ^a,b   Du, P ^b   Paskaranandavadivel, N ^b   Angeli, T R ^b   Lammers, W J E P ^b,c   Asirvatham, S J ^d   Windsor, J A ^a   Farrugia, G ^d   Pullan, A J ^a,b,e   Cheng, L K ^b,e  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c UNITED ARAB EMIRATES UNIVERSITY   (United Arab Emirates)

^d MAYO CLINIC   (United States)

^e VANDERBILT UNIVERSITY   (United States)

Author keywords

Arrhythmia; Computational model; Gastric electrical activity; High resolution mapping; Mathematical model

Indexed keywords

AMPLITUDE MODULATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; EXPERIMENTAL PIG; FEMALE; GASTRIC DYSMOTILITY; INTERSTITIAL CELL OF CAJAL; MATHEMATICAL MODEL; MEMBRANE POTENTIAL; MYENTERIC PLEXUS; NERVE CONDUCTION; NONHUMAN; PRIORITY JOURNAL; SIMULATION; STOMACH MOTILITY;

ANIMALS; ELECTROPHYSIOLOGY; FEMALE; INTERSTITIAL CELLS OF CAJAL; MEMBRANE POTENTIALS; MODELS, THEORETICAL; MUSCLE, SMOOTH; MYOELECTRIC COMPLEX, MIGRATING; STOMACH; SUBMUCOUS PLEXUS; SWINE;

EID: 84862689179     PISSN: 13501925     EISSN: 13652982     Source Type: Journal    
DOI: 10.1111/j.1365-2982.2012.01932.x     Document Type: Article

References (38)

1. Huizinga JD, Lammers WJEP. Gut peristalsis is coordinated by a multitude of cooperating mechanisms. Am J Physiol Gastrointest Liver Physiol 2009; 296: 1-8.
2. Lammers WJ, Ver Donck L, Stephen B, Smets D, Schuurkes JA. Origin and propagation of the slow wave in the canine stomach: the outlines of a gastric conduction system. Am J Physiol Gastrointest Liver Physiol 2009; 296: 1200-10.
3. O'Grady G, Du P, Cheng LK et al. The origin and propagation of human gastric slow wave activity defined by high-resolution mapping. Am J Physiol Gastrointest Liver Physiol 2010; 299: 585-92.
4. Egbuji JU, O'Grady G, Du P et al. Origin, propagation and regional characteristics of porcine gastric slow wave activity determined by high-resolution mapping. Neurogastroenterol Motil 2010; 22: e292-300.
5. Du P, O'Grady G, Cheng LK, Pullan AJ. A multi-scale model of the electrophysiological basis of the human electrogastrogram. Biophys J 2010; 99: 2784-92.
6. Lammers WJEP, Ver Donck L, Stephen B, Smets D, Schuurkes JAJ. Focal activities and re-entrant propagations as mechanisms of gastric tachyarrhythmias. Gastroenterology 2008; 135: 1601-11.
7. O'Grady G, Egbuji JU, Du P et al. High-resolution spatial analysis of slow wave initiation and conduction in porcine gastric dysrhythmia. Neurogastroenterol Motil 2011; 23: e345-55.
8. Paskaranandavadivel N, Cheng LK, Du P, O'Grady G, Pullan AJ. Improved signal processing techniques for the analysis of high resolution serosal slow wave activity in the stomach. Conf Proc IEEE Eng Med Biol Soc 2011; 1737-40.
9. Paskaranandavadivel N, O'Grady G, Du P, Pullan AJ, Cheng LK. An improved method for the estimation and visualization of velocity fields from gastric high-resolution electrical mapping. IEEE Trans Biomed Eng 2012; 59: 882-9.
10. Du P, O'Grady G, Egbuji JU et al. High-resolution mapping of in vivo gastrointestinal slow wave activity using flexible printed circuit board electrodes: methodology and validation. Ann Biomed Eng 2009; 37: 839-46.
11. O'Grady G, Du P, Lammers WJ et al. High-resolution entrainment mapping for gastric pacing: a new analytic tool. Am J Physiol Gastrointest Liver Physiol 2010; 298: 314-21.
12. Yassi R, O'Grady G, Du P et al. Gastric Electrical Mapping Suite (GEMS) [Computer Program]. Version 1.3. Auckland, New Zealand. 2011. Available at:
13. Erickson JC, O'Grady G, Du P et al. Falling-edge, variable threshold (FEVT) method for the automated detection of gastric slow wave events in serosal high-resolution electrical recordings. Ann Biomed Eng 2010; 38: 1511-29.
14. Erickson JC, O'Grady G, Du P, Egbuji JU, Pullan AJ, Cheng LK. Automated cycle partitioning and visualization of high-resolution activation time maps of gastric slow wave recordings: the Region Growing Using Polynomial Surface-estimate stabilization (REGROUPS) Algorithm. Ann Biomed Eng 2011; 39: 469-83.
15. Lammers WJ, Stephen B, Slack JR, Dhanasekaran S. Anisotropic propagation in the small intestine. Neurogastroenterol Motil 2002; 14: 357-64.
16. Hirst GD, Garcia-Londono AP, Edwards FR. Propagation of slow waves in the guinea-pig gastric antrum. J Physiol 2006; 571: 165-77.
17. Edwards FR, Hirst GD. An electrical analysis of slow wave propagation in the guinea-pig gastric antrum. J Physiol 2006; 571: 179-89.
18. Hirst GD, Edwards FR. Electrical events underlying organized myogenic contractions of the guinea pig stomach. J Physiol 2006; 576: 659-65.
19. Du P, O'Grady G, Davidson JB, Cheng LK, Pullan AJ. Multiscale modeling of gastrointestinal electrophysiology and experimental validation. Crit Rev Biomed Eng 2010; 38: 1-30.
20. Corrias A, Buist ML. A quantitative model of gastric smooth muscle cellular activation. Ann Biomed Eng 2007; 35: 1595-607.
21. Hennig GW, Hirst GD, Park KJ et al. Propagation of pacemaker activity in the guinea-pig antrum. J Physiol 2004; 556: 585-99.
22. Park KJ, Hennig GW, Lee HT et al. Spatial and temporal mapping of pacemaker activity in interstitial cells of Cajal in mouse ileum in situ. Am J Physiol Cell Physiol 2006; 290: C1411-27.
23. Spach MS, Miller WTr, Miller-Jones E, Warren RB, Barr RC. Extracellular potentials related to intracellular action potentials during impulse conduction in anisotropic canine cardiac muscle. Circ Res 1979; 45: 188-204.
24. Bortoff A. Configuration of intestinal slow waves obtained by monopolar recording techniques. Am J Physiol 1967; 213: 157-62.
25. Cohen I, Miles R. Contributions of intrinsic and synaptic activities to the generation of neuronal discharges in in vitro hippocampus. J Physiol 2000; 524(Pt 2): 485-502.
26. Grover M, Farrugia G, Lurken MS et al. Cellular changes in diabetic and idiopathic gastroparesis. Gastroenterology 2011; 140: 1575-85.
27. Jacobi S, Moses E. Variability and corresponding amplitude-velocity relation of activity propagating in one-dimensional neural cultures. J Neurophysiol 2007; 97: 3597-606.
28. Familoni BO, Abell TL, Bowes KL. A model of gastric electrical activity in health and disease. IEEE Trans Biomed Eng 1995; 42: 647-57.
29. Liang JIE, Chen JDZ. What can be measured from surface electrogastrography (computer simulations). Dig Dis Sci 1997; 42: 1331-43.
30. Coleski R, Hasler WL. Coupling and propagation of normal and dysrhythmic gastric slow waves during acute hyperglycaemia in healthy humans. Neurogastroenterol Motil 2009; 21: 492-9.
31. Hocking MP, Vogel SB, Sninsky CA. Human gastric myoelectric activity and gastric emptying following gastric surgery and with pacing. Gastroenterology 1992; 103: 1811-6.
32. de Bakker JM, Wittkampf FH. The pathophysiologic basis of fractionated and complex electrograms and the impact of recording techniques on their detection and interpretation. Circ Arrhythm Electrophysiol 2010; 3: 204-13.
33. Cheng LK, O'Grady G, Du P, Egbuji J, Windsor JA, Pullan AJ. Gastrointestinal System. Wiley Interdisciplin Rev Syst Biol Med 2010; 2: 65-79.
34. Jimenez M, Borderies JR, Vergara P, Wang Y, Daniel EE. Slow waves in circular muscle of porcine ileum: structural and electrophysiological studies. Am J Physiol 1999; 276: G393-406.
35. Barr RC, Plonsey R. Bioelectricity: A Quantitative Approach, 3rd edn. New York: Springer, 2007.
36. Plonsey R. The formulation of bioelectric source-field relationship in terms of surface discontinuities. J Franklin Inst 1974; 297: 317-24.
37. Huh CH, Bhutani MS, Farfan EB, Bolch WE. Individual variations in mucosa and total wall thickness in the stomach and rectum assessed via endoscopic ultrasound. Physiol Meas 2003; 24: N15-22.
38. Buist ML, Cheng LK, Yassi R, Bradshaw LA, Richards WO, Pullan AJ. An anatomical model of the gastric system for producing bioelectric and biomagnetic fields. Physiol Meas 2004; 25: 849-61.