Spatial and temporal mapping of pacemaker activity in interstitial cells of Cajal in mouse ileum in situ

American Journal of Physiology - Cell Physiology

Volumn 290, Issue 5, 2006, Pages

  Park, Kyu Joo ^a   Hennig, Grant W ^a   Lee, Hyun Tai ^a   Spencer, Nick J ^a   Ward, Sean M ^a   Smith, Terence K ^a   Sanders, Kenton M ^a  

^a UNIVERSITY OF NEVADA SCHOOL OF MEDICINE   (United States)

Author keywords

Ca2+ signaling; Gastrointestinal motility; Slow waves

Indexed keywords

2 AMINOETHOXYDIPHENYLBORANE; ANTIBODY; CALCIUM; CALCIUM CHANNEL BLOCKING AGENT; CARBONYL CYANIDE 4 (TRIFLUOROMETHOXY)PHENYLHYDRAZONE; CITRININ; DIHYDROPYRIDINE; FLUORESCENT DYE; GLYCYRRHETINIC ACID; INOSITOL 1,4,5 TRISPHOSPHATE RECEPTOR; MIBEFRADIL; NICARDIPINE; NICKEL; PINACIDIL; POTASSIUM; STEM CELL FACTOR; UNCOUPLING PROTEIN; VOLTAGE GATED CALCIUM CHANNEL;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL ACTIVITY; CONTROLLED STUDY; FEMALE; GASTROINTESTINAL MOTILITY; ILEUM; INTERSTITIAL CELL OF CAJAL; MALE; MOUSE; MUSCLE CELL; MYENTERIC PLEXUS; NONHUMAN; PACEMAKER; PRIORITY JOURNAL; SMALL INTESTINE; WAVEFORM;

ACTION POTENTIALS; ANIMALS; BIOLOGICAL CLOCKS; CALCIUM SIGNALING; CELLS, CULTURED; FEMALE; ILEUM; MALE; MICE; MICE, INBRED C57BL; MICROSCOPY, FLUORESCENCE; MYOCYTES, SMOOTH MUSCLE;

MURINAE;

EID: 33646400585     PISSN: 03636143     EISSN: 15221563     Source Type: Journal    
DOI: 10.1152/ajpcell.00447.2005     Document Type: Article

References (44)

1. Bauer AJ, Publicover NG, and Sanders KM. Origin and spread of slow waves in canine gastric antral circular muscle. Am J Physiol Gastrointest Liver Physiol 249: G800-G806, 1985.
2. Conklin JL and Du C. Pathways of slow-wave propagation in proximal colon of cats. Am J Physiol Gastrointest Liver Physiol 258: G894-G903, 1990.
3. Cousins HM, Edwards FR, Hickey H, Hill CE, and Hirst GDS. Electrical coupling between the myenteric interstitial cells of adjacent muscle layers in the guinea-pig gastric antrum. J Physiol 550: 829-844, 2003.
4. Daniel EE and Wang YF. Gap junctions in intestinal smooth muscle and interstitial cells of Cajal. Microsc Res Tech 47: 309-320, 1999.
5. Davidson JS and Baumgarten IM. Glycyrrhetinic acid derivatives: a novel class of inhibitors of gap-junctional intercellular communication. Structure-activity relationships. J Pharmacol Exp Ther 246: 1104-1107, 1988.
6. Dickens EJ, Hirst GDS, and Tomita T. Identification of rhythmically active cells in guinea-pig stomach. J Physiol 514: 515-531, 1999.
7. Edwards FR and Hirst GDS. An electrical description of the generation of slow waves in the antrum of the guinea-pig. J Physiol 564: 213-232, 2005.
8. Goto K, Matsuoka S, and Noma A. Two types of spontaneous depolarizations in the interstitial cells freshly prepared from the murine small intestine. J Physiol 559: 411-422, 2004.
9. Hennig GW, Hirst GDS, Park KJ, Smith CB, Sanders KM, Ward SM, and Smith TK. Propagation of pacemaker activity in the guinea-pig antrum. J Physiol 556: 585-599, 2004.
10. 2+ waves in the longitudinal muscle layer of the murine large intestine in vitro. J Physiol 543: 233-253, 2002.
11. - channels. J Physiol 540: 907-919, 2002.
12. Hirst GDS and Edwards FR. Generation of slow waves in the antral region of guinea-pig stomach: a stochastic process. J Physiol 535: 165-180, 2001.
13. Horiguchi K and Komuro T. Ultrastructural characterization of interstitial cells of Cajal in the rat small intestine using control and Ws/Ws mutant rats. Cell Tissue Res 293: 277-284, 1998.
14. Horowitz B, Ward SM, and Sanders KM. Cellular and molecular basis for electrical rhythmicity in gastrointestinal muscles. Annu Rev Physiol 61: 19-43, 1999.
15. Huizinga JD, Thuneberg L, Klüppel M, Malysz J, Mikkelsen HB, and Bernstein A. W/kit gene required for interstitial cells of Cajal and for intestinal pacemaker activity. Nature 373: 347-349, 1995.
16. 2+ oscillations. Biophys J 90: 1-23, 2006.
17. Kim YC, Koh SD, and Sanders KM. Voltage-dependent inward currents of interstitial cells of Cajal from murine colon and small intestine. J Physiol 541: 797-810, 2002.
18. Kito Y and Suzuki H. Properties of pacemaker potentials recorded from myenteric interstitial cells of Cajal distributed in the mouse small intestine. J Physiol 553: 803-818, 2003.
19. Kito Y, Ward SM, and Sanders KM. Pacemaker potentials generated by interstitial cells of Cajal in the murine intestine. Am J Physiol Cell Physiol 288: C710-C720, 2005.
20. 2+-inhibited non-selective cation conductance contributes to pacemaker currents in mouse interstitial cell of Cajal. J Physiol 540: 803-814, 2002.
21. Lammers WJ, Donck LV, Schuurkes JA, and Stephen B. Longitudinal and circumferential spike patches in the canine small intestine in vivo. Am J Physiol Gastrointest Liver Physiol 285: G1014-G1027, 2003.
22. Lee HK and Sanders KM. Comparison of ionic currents from interstitial cells and smooth muscle cells of canine colon. J Physiol 460: 135-152, 1993.
23. Ördög T, Ward SM, and Sanders KM. Interstitial cells of Cajal generate electrical slow waves in the murine stomach. J Physiol 518: 257-269, 1999.
24. 2+, and tension in intact smooth muscles. Am J Physiol Cell Physiol 260: C917-C925, 1991.
25. Publicover NG and Sanders KM. Are relaxation oscillators an appropriate model of gastrointestinal electrical activity? Am J Physiol Gastrointest Liver Physiol 256: G265-G274, 1989.
26. Sanders KM, Koh SD, and Ward SM. Interstitial cells of Cajal as pacemakers in the gastrointestinal tract. Annu Rev Physiol 68: 307-343, 2006.
27. Sanders KM, Ördög T, Koh SD, and Ward SM. A novel pacemaker mechanism drives gastrointestinal rhythmicity. News Physiol Sci 15: 291-298, 2000.
28. Sanders KM, Stevens R, Burke E, and Ward SW. Slow waves actively propagate at submucosal surface of circular layer in canine colon. Am J Physiol Gastrointest Liver Physiol 259: G258-G263, 1990.
29. Seerden TC, Lammers WJ, De Winter BY, De Man JG, and Pelckmans PA. Spatiotemporal electrical and motility mapping of distension-induced propagating oscillations in the murine small intestine. Am J Physiol Gastrointest Liver Physiol 289: G1043-G1051, 2005.
30. Seki K, Zhou DS, and Komuro T. Immunohistochemical study of the c-kit expressing cells and connexin 43 in the guinea-pig digestive tract. J Auton Nerv Syst 68: 182-187, 1998.
31. 2+ waves by enteric neural reflexes. Nature 399: 62-66, 1999.
32. Suzuki N, Prosser CL, and Dahms V. Boundary cells between longitudinal and circular layers: essential for electrical slow waves in cat intestine. Am J Physiol Gastrointest Liver Physiol 250: G287-G294, 1986.
33. Szurszewski JH. Electrical basis for gastrointestinal motility. In: Physiology of the Gastrointestinal Tract (2nd ed.), edited by Johnson LR. New York: Raven, 1987, vol. 1, p. 383-422.
34. Tack J and Smith TK. Calcium imaging of gut activity. Neurogastroenterol Motil 16: 86-95, 2004.
35. Thuneberg L. Interstitial cells of Cajal: intestinal pacemaker cells? Adv Anat Embryol Cell Biol 71: 1-130, 1982.
36. Tomita T. Electrical activity (spikes and slow waves) in gastrointestinal smooth muscles. In: Smooth Muscle: An Assessment of Current Knowledge, edited by Bülbring E, Brading AF, Jones AW, and Tomita T. London: Arnold, 1981, p. 127-156.
37. Torihashi S, Ward SM, Nishikawa SI, Nishi K, Kobayashi S, and Sanders KM. c-Kit-dependent development of interstitial cells and electrical activity in the murine gastrointestinal tract. Cell Tissue Res 280: 97-111, 1995.
38. 2+ phase waves: a basis for cellular pacemaking and long-range synchronicity in the guinea-pig gastric pylorus. J Physiol 548: 271-296, 2003.
39. Van Helden DF, Imatiaz MS, Nurgaliyeva K, von der Weid PY, and Dosen PJ. Role of calcium stores and membrane voltage in the generation of slow wave action potentials in guinea-pig gastric pylorus. J Physiol 524: 245-265, 2000.
40. Ward SM, Burns AJ, Torihashi S, and Sanders KM. Mutation of the proto-oncogene c-kit blocks development of interstitial cells and electrical rhythmicity in murine intestine. J Physiol 480: 91-97, 1994.
41. Ward SM, Dixon RE, de Faoite A, and Sanders KM. Voltage-dependent calcium entry underlies propagation of slow waves in canine gastric antrum. J Physiol 561: 793-810, 2004.
42. Ward SM, Ördög T, Koh SD, Baker SA, Jun JY, Amberg G, Monaghan K, and Sanders KM. Pacemaking in interstitial cells of Cajal depends upon calcium handling by endoplasmic reticulum and mitochondria. J Physiol 525: 355-361, 2000.
43. Yamamoto Y, Fukuta H, Nakahira Y, and Suzuki H. Blockade by 18β-glycyrrhetinic acid of intercellular electrical coupling in guinea-pig arterioles. J Physiol 511: 501-508, 1998.
44. 2+ signals in interstitial cells of Cajal and longitudinal smooth muscle cells during rhythmic activity in mouse ileum. J Physiol 538: 823-835, 2002.