Pharmacokinetics of tenofovir following intravaginal and intrarectal administration of tenofovir gel to rhesus macaques

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 1, 2012, Pages 103-109

  Nuttall, Jeremy ^a   Kashuba, Angela ^b   Wang, Ruili ^b   White, Nicole ^b   Allen, Philip ^c   Roberts, Jeffrey ^c   Romano, Joseph ^a,d  

^a INTERNATIONAL PARTNERSHIP FOR MICROBICIDES   (United States)

^b UNIVERSITY OF NORTH CAROLINA   (United States)

^c Valley Biosystems   (United States)

^d NWJ Group LLC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

TENOFOVIR;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; DOSE RESPONSE; DRUG BLOOD LEVEL; DRUG DISTRIBUTION; DRUG DOSE INCREASE; DRUG FORMULATION; DRUG TISSUE LEVEL; FEMALE; GEL; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RECTUM BIOPSY; RHESUS MONKEY; TIME TO MAXIMUM PLASMA CONCENTRATION; UTERINE CERVIX BIOPSY; VAGINA;

ADENINE; ADMINISTRATION, INTRAVAGINAL; ADMINISTRATION, RECTAL; ANIMALS; ANTIVIRAL AGENTS; AREA UNDER CURVE; BODY FLUIDS; DOSE-RESPONSE RELATIONSHIP, DRUG; FEMALE; GELS; HIV INFECTIONS; HIV-1; HUMANS; MACACA MULATTA; PHOSPHONIC ACIDS; RECTUM; SIMIAN ACQUIRED IMMUNODEFICIENCY SYNDROME; SIMIAN IMMUNODEFICIENCY VIRUS; VAGINA;

EID: 84455192446     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00597-11     Document Type: Article

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