Candidate microbicide PPCM blocks human immunodeficiency virus type 1 infection in cell and tissue cultures and prevents genital herpes in a murine model

Journal of Virology

Volumn 82, Issue 13, 2008, Pages 6576-6584

  Mesquita, Pedro M M ^a,b   Wilson, Sarah S ^b   Manlow, Philippe ^a   Fischetti, Lucia ^a   Keller, Maria J ^b   Herold, Betsy C ^b   Shattock, Robin J ^a  

^a ST GEORGE'S UNIVERSITY OF LONDON   (United Kingdom)

^b ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MANDELIC ACID; MICROBICIDE; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE; PLACEBO; PPCM; RNA DIRECTED DNA POLYMERASE INHIBITOR; SULFURIC ACID; TENOFOVIR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIVIRAL ACTIVITY; ARTICLE; CELL CULTURE; CLADISTICS; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG EFFICACY; EXPLANT; GEL; GENITAL HERPES; HERPES SIMPLEX VIRUS; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN TISSUE; IC 50; NONHUMAN; PRIORITY JOURNAL; SEMINAL PLASMA; T LYMPHOCYTE; TISSUE CULTURE; VIRUS INHIBITION; VIRUS PLAQUE;

ANIMALS; ANTI-INFECTIVE AGENTS; GELS; HELA CELLS; HERPES GENITALIS; HIV INFECTIONS; HIV-1; HUMANS; INHIBITORY CONCENTRATION 50; LUCIFERASES; MANDELIC ACIDS; MICE; SIMPLEXVIRUS; SULFURIC ACIDS;

HERPES; HERPESVIRIDAE; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; MURINAE; MUS; SIMPLEXVIRUS;

EID: 45749114155     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.00335-08     Document Type: Article

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