Potential of healing a transected anterior cruciate ligament with genetically modified extracellular matrix bioscaffolds in a goat model

Knee Surgery, Sports Traumatology, Arthroscopy

Volumn 20, Issue 7, 2012, Pages 1357-1365

  Fisher, Matthew B ^a   Liang, Rui ^a   Jung, Ho Joong ^a,b   Kim, Kwang E ^a   Zamarra, Giovanni ^a   Almarza, Alejandro J ^a   McMahon, Patrick J ^a   Woo, Savio L Y ^a  

^a PA 15260   (United States)

^b Chung Ang University   (South Korea)

Author keywords

Anterior cruciate ligament (ACL); Biomechanics; Extracellular matrix (ECM) bioscaffolds; Functional tissue engineering; Robotic testing system

Indexed keywords

GALACTOSYLTRANSFERASE; TISSUE SCAFFOLD;

ANIMAL; ANIMAL MODEL; ANTERIOR CRUCIATE LIGAMENT; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; ARTICLE; BIOMECHANICS; EXTRACELLULAR MATRIX; GOAT; HYDROGEL; INJURY; MATERIALS TESTING; METHODOLOGY; PROSTHESES AND ORTHOSES; SWINE; TISSUE ENGINEERING; TISSUE REGENERATION;

ANIMALS; ANTERIOR CRUCIATE LIGAMENT; ANTERIOR CRUCIATE LIGAMENT RECONSTRUCTION; BIOMECHANICS; EXTRACELLULAR MATRIX; GALACTOSYLTRANSFERASES; GOATS; GUIDED TISSUE REGENERATION; HYDROGEL; MATERIALS TESTING; MODELS, ANIMAL; PROSTHESES AND IMPLANTS; SWINE; TISSUE ENGINEERING; TISSUE SCAFFOLDS;

EID: 84862671223     PISSN: 09422056     EISSN: 14337347     Source Type: Journal    
DOI: 10.1007/s00167-011-1800-x     Document Type: Article

References (45)

1. Abramowitch SD, Papageorgiou CD, Withrow JD, Gilbert TW, Woo SL-Y (2003) The effect of initial graft tension on the biomechanical properties of a healing ACL replacement graft: a study in goats. J Orthop Res 21(4): 708-715.
2. Agung M, Ochi M, Yanada S et al (2006) Mobilization of bone marrow-derived mesenchymal stem cells into the injured tissues after intraarticular injection and their contribution to tissue regeneration. Knee Surg Sports Traumatol Arthrosc 14(12): 1307-1314.
3. Anderson AF, Snyder RB, Lipscomb AB Jr (2001) Anterior cruciate ligament reconstruction. A prospective randomized study of three surgical methods. Am J Sports Med 29(3): 272-279.
4. Anitua E, Sanchez M, Orive G, Andia I (2007) The potential impact of the preparation rich in growth factors (PRGF) in different medical fields. Biomaterials 28(31): 4551-4560.
5. Badylak SF (2007) The extracellular matrix as a biologic scaffold material. Biomaterials 28(25): 3587-3593.
6. Chen G, Qian H, Starzl T et al (2005) Acute rejection is associated with antibodies to non-Gal antigens in baboons using Gal-knockout pig kidneys. Nat Med 11(12): 1295-1298.
7. Cummings JF, Grood ES (2002) The progression of anterior translation after anterior cruciate ligament reconstruction in a caprine model. J Orthop Res 20(5): 1003-1008.
8. Dai Y, Vaught TD, Boone J et al (2002) Targeted disruption of the alpha1, 3-galactosyltransferase gene in cloned pigs. Nat Biotechnol 20(3): 251-255.
9. Drogset JO, Grontvedt T, Robak OR et al (2006) A 16-year follow-up of three operative techniques for the treatment of acute ruptures of the anterior cruciate ligament. J Bone Jt Surg Am 88(5): 944-952.
10. Feagin JA Jr, Curl WW (1976) Isolated tear of the anterior cruciate ligament: 5-year follow-up study. Am J Sports Med 4(3): 95-100.
11. Fisher MB, Jung HJ, McMahon PJ, Woo SL-Y (2010) Evaluation of bone tunnel placement for suture augmentation of an injured anterior cruciate ligament: effects on joint stability in a goat model. J Orthop Res 28(10): 1373-1379.
12. Freytes DO, Martin J, Velankar SS, Lee AS, Badylak SF (2008) Preparation and rheological characterization of a gel form of the porcine urinary bladder matrix. Biomaterials 29(11): 1630-1637.
13. Gilbert TW, Stolz DB, Biancaniello F, Simmons-Byrd A, Badylak SF (2005) Production and characterization of ECM powder: implications for tissue engineering applications. Biomaterials 26(12): 1431-1435.
14. Gobbi A, Bathan L, Boldrini L (2009) Primary repair combined with bone marrow stimulation in acute anterior cruciate ligament lesions: results in a group of athletes. Am J Sports Med 37(3): 571-578.
15. Iannotti JP, Codsi MJ, Kwon YW et al (2006) Porcine small intestine submucosa augmentation of surgical repair of chronic two-tendon rotator cuff tears. A randomized, controlled trial. J Bone Jt Surg Am 88(6): 1238-1244.
16. Jomha NM, Borton DC, Clingeleffer AJ, Pinczewski LA (1999) Long-term osteoarthritic changes in anterior cruciate ligament reconstructed knees. Clin Orthop Relat Res 358: 188-193.
17. Joshi SM, Mastrangelo AN, Magarian EM, Fleming BC, Murray MM (2009) Collagen-platelet composite enhances biomechanical and histologic healing of the porcine anterior cruciate ligament. Am J Sports Med 37(12): 2401-2410.
18. Kaplan N, Wickiewicz TL, Warren RF (1990) Primary surgical treatment of anterior cruciate ligament ruptures. A long-term follow-up study. Am J Sports Med 18(4): 354-358.
19. Karaoglu S, Fisher MB, Woo SL-Y et al (2008) Use of a bioscaffold to improve healing of a patellar tendon defect after graft harvest for ACL reconstruction: a study in rabbits. J Orthop Res 26(2): 255-263.
20. Kuwaki K, Tseng YL, Dor FJ et al (2005) Heart transplantation in baboons using alpha1, 3-galactosyltransferase gene-knockout pigs as donors: initial experience. Nat Med 11(1): 29-31.
21. Lee TQ, Woo SL-Y (1988) A new method for determining cross-sectional shape and area of soft tissues. J Biomech Eng 110(2): 110-114.
22. Li G, van de Velde SK, Bingham JT (2008) Validation of a non-invasive fluoroscopic imaging technique for the measurement of dynamic knee joint motion. J Biomech 41(7): 1616-1622.
23. Liang R, Fisher M, Yang G, Hall C, Woo SL-Y (2011) Alpha1, 3-galactosyltransferase knockout does not alter the properties of porcine extracellular matrix bioscaffolds. Acta Biomater 7(4): 1719-1727.
24. Liang R, Woo SL-Y, Takakura Y et al (2006) Long-term effects of porcine small intestine submucosa on the healing of medial collateral ligament: a functional tissue engineering study. J Orthop Res 24(4): 811-819.
25. Livesay GA, Fujie H, Kashiwaguchi S et al (1995) Determination of the in situ forces and force distribution within the human anterior cruciate ligament. Ann Biomed Eng 23(4): 467-474.
26. Ma CB, Papageogiou CD, Debski RE, Woo SL-Y (2000) Interaction between the ACL graft and MCL in a combined ACL + MCL knee injury using a goat model. Acta Orthop Scand 71(4): 387-393.
27. Malcarney HL, Bonar F, Murrell GA (2005) Early inflammatory reaction after rotator cuff repair with a porcine small intestine submucosal implant: a report of 4 cases. Am J Sports Med 33(6): 907-911.
28. Ng GY, Oakes BW, Deacon OW, McLean ID, Lampard D (1995) Biomechanics of patellar tendon autograft for reconstruction of the anterior cruciate ligament in the goat: 3-year study. J Orthop Res 13(4): 602-608.
29. Papageorgiou CD, Gil JE, Kanamori A et al (2001) The biomechanical interdependence between the anterior cruciate ligament replacement graft and the medial meniscus. Am J Sports Med 29(2): 226-231.
30. Phelps CJ, Koike C, Vaught TD et al (2003) Production of alpha 1, 3-galactosyltransferase-deficient pigs. Science 299(5605): 411-414.
31. Reing JE, Zhang L, Myers-Irvin J et al (2009) Degradation products of extracellular matrix affect cell migration and proliferation. Tiss Eng Part A 15(3): 605-614. doi: 10. 1089/ten. tea. 2007. 0425.
32. Sakane M, Livesay GA, Fox RJ et al (1999) Relative contribution of the ACL, MCL, and bony contact to the anterior stability of the knee. Knee Surg Sports Traumatol Arthrosc 7(2): 93-97.
33. Scherping SC Jr, Schmidt CC, Georgescu HI et al (1997) Effect of growth factors on the proliferation of ligament fibroblasts from skeletally mature rabbits. Connect Tiss Res 36(1): 1-8.
34. Spindler KP, Kuhn JE, Freedman KB et al (2004) Anterior cruciate ligament reconstruction autograft choice: bone-tendon-bone versus hamstring: does it really matter? A systematic review. Am J Sports Med 32(8): 1986-1995.
35. Steadman JR, Cameron-Donaldson ML, Briggs KK, Rodkey WG (2006) A minimally invasive technique ("healing response") to treat proximal ACL injuries in skeletally immature athletes. J Knee Surg 19(1): 8-13.
36. Torry MR, Shelburne KB, Peterson DS et al (2011) Knee kinematic profiles during drop landings: a biplane fluoroscopy study. Med Sci Sports Exerc 43(3): 533-541.
37. Vorotnikova E, McIntosh D, Dewilde A et al (2010) Extracellular matrix-derived products modulate endothelial and progenitor cell migration and proliferation in vitro and stimulate regenerative healing in vivo. Matrix Biol 29(8): 690-700.
38. Warren RF (1983) Primary repair of the anterior cruciate ligament. Clin Orthop Relat Res 172: 65-70.
39. Wiig ME, Amiel D, VandeBerg J et al (1990) The early effect of high molecular weight hyaluronan (hyaluronic acid) on anterior cruciate ligament healing: an experimental study in rabbits. J Orthop Res 8(3): 425-434.
40. Woo SL-Y, Abramowitch SD, Kilger R, Liang R (2006) Biomechanics of knee ligaments: injury, healing, and repair. J Biomech 39(1): 1-20.
41. Woo SL-Y, Danto MI, Ohland KJ, Lee TQ, Newton PO (1990) The use of a laser micrometer system to determine the cross-sectional shape and area of ligaments: a comparative study with two existing methods. J Biomech Eng 112(4): 426-431.
42. Woo SL-Y, Hollis JM, Adams DJ, Lyon RM, Takai S (1991) Tensile properties of the human femur-anterior cruciate ligament-tibia complex: the effects of specimen age and orientation. Am J Sports Med 19(3): 217-225.
43. Woo SL-Y, Peterson RH, Ohland KJ, Sites TJ, Danto MI (1990) The effects of strain rate on the properties of the medial collateral ligament in skeletally immature and mature rabbits: a biomechanical and histological study. J Orthop Res 8(5): 712-721.
44. Woo SL-Y, Takakura Y, Liang R, Jia F, Moon DK (2006) Treatment with bioscaffold enhances the fibril morphology and the collagen composition of healing medial collateral ligament in rabbits. Tiss Eng 12(1): 159-166.
45. Yamada K, Yazawa K, Shimizu A et al (2005) Marked prolongation of porcine renal xenograft survival in baboons through the use of alpha1, 3-galactosyltransferase gene-knockout donors and the cotransplantation of vascularized thymic tissue. Nat Med 11(1): 32-34.