Adaptive optimal design for bridging studies with an application to population pharmacokinetic studies

Pharmaceutical Research

Volumn 29, Issue 6, 2012, Pages 1530-1543

  Foo, Lee Kien ^a   Duffull, Stephen ^a  

^a UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

adaptive design; bridging studies; optimal design; pharmacokinetics

Indexed keywords

ANALYTIC METHOD; ARTICLE; BODY WEIGHT; CLINICAL PRACTICE; CRITERION VARIABLE; HUMAN; MATHEMATICAL ANALYSIS; MATHEMATICAL MODEL; MEDICAL RESEARCH; PATIENT SELECTION; PHARMACOKINETICS; POPULATION DYNAMICS; POPULATION MODEL; POPULATION RESEARCH; PRIORITY JOURNAL; PROCESS DESIGN; PROCESS OPTIMIZATION; SIMULATION;

ADULT; AGE FACTORS; BODY WEIGHT; CHEMISTRY, PHARMACEUTICAL; CHILD; COMPUTER SIMULATION; DRUG DOSAGE CALCULATIONS; HUMANS; MODELS, BIOLOGICAL; OBESITY; PHARMACEUTICAL PREPARATIONS; PHARMACOKINETICS; RESEARCH DESIGN;

EID: 84862668979     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-011-0659-3     Document Type: Article

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