Adaptive designs for dose-finding studies based on sigmoid Emax model

Journal of Biopharmaceutical Statistics

Volumn 17, Issue 6, 2007, Pages 1051-1070

  Dragalin, Vladimir ^a   Hsuan, Francis ^b   Padmanabhan, S Krishna ^a,b  

^a PFIZER INC   (United States)

^b TEMPLE UNIVERSITY   (United States)

Author keywords

Adaptive design; D optimal design; Dose finding; Four parameter logistic function

Indexed keywords

ANALYSIS OF VARIANCE; CLINICAL RESEARCH; CLINICAL STUDY; COMPUTER SIMULATION; CONFERENCE PAPER; FISHER EXACT TEST; LOGISTIC REGRESSION ANALYSIS; MATHEMATICAL ANALYSIS; MEDICAL INFORMATION; PRIORITY JOURNAL;

CLINICAL TRIALS AS TOPIC; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HUMANS; LIKELIHOOD FUNCTIONS; MODELS, STATISTICAL; RESEARCH DESIGN;

EID: 36248976637     PISSN: 10543406     EISSN: 15205711     Source Type: Journal    
DOI: 10.1080/10543400701643954     Document Type: Conference Paper

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