Endocrine-mediated effects of two benzene related compounds, 1-chloro-4-(chloromethyl)benzene and 1,3-diethyl benzene, based on subacute oral toxicity studies using rats

Food and Chemical Toxicology

Volumn 50, Issue 8, 2012, Pages 2635-2642

  Yamasaki, Kanji ^a   Ishii, Satoko ^a   Kikuno, Tsukasa ^a   Minobe, Yasushi ^a  

^a CHEMICALS EVALUATION AND RESEARCH INSTITUTE   (Japan)

Author keywords

1,3 Diethyl benzene; 1 Chloro 4 (chloromethyl)benzene; Endocrine effects; OECD Test Guideline No. 407; Rat

Indexed keywords

1 CHLORO 4 (CHLOROMETHYL)BENZENE; 1,3 DIETHYLBENZENE; BENZENE DERIVATIVE; THYROTROPIN; THYROXINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOCRINE DISEASE; FEMALE; HORMONE ACTION; MALE; NONHUMAN; RAT; SUBACUTE ORAL TOXICITY; THYROID DISEASE; THYROID FOLLICLE CELL; THYROID HYPERPLASIA; THYROID WEIGHT; THYROTROPIN BLOOD LEVEL; THYROXINE BLOOD LEVEL; TOXICITY TESTING;

ADMINISTRATION, ORAL; ANIMALS; BENZENE DERIVATIVES; BODY WEIGHT; CHLOROBENZENES; FEEDING BEHAVIOR; FEMALE; MALE; ORGAN SIZE; RATS; RATS, SPRAGUE-DAWLEY; THYROID GLAND; THYROID HORMONES; TOXICITY TESTS, SUBACUTE;

RATTUS;

EID: 84862658383     PISSN: 02786915     EISSN: 18736351     Source Type: Journal    
DOI: 10.1016/j.fct.2012.05.035     Document Type: Article

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