Uterotrophic and Hershberger assays for n-butylbenzene in rats

Archives of Toxicology

Volumn 75, Issue 11, 2002, Pages 703-706

  Yamasaki, Kanji ^a   Sawaki, Masakuni ^a   Noda, Shuji ^a   Takatsuki, Mineo ^a  

^a CHEMICALS EVALUATION AND RESEARCH INSTITUTE   (Japan)

Author keywords

Ethynylestradiol; Hershberger assay; n Butylbenzene; Testosterone propionate; Uterotrophic assay

Indexed keywords

BENZENE DERIVATIVE; BUTYLBENZENE; TESTOSTERONE PROPIONATE; UNCLASSIFIED DRUG;

ACCESSORY SEX ORGAN; ANIMAL TISSUE; ARTICLE; ASSAY; BODY WEIGHT; CASTRATION; CONTROLLED STUDY; FEMALE; LEVATOR ANI MUSCLE; LIVER WEIGHT; MALE; NONHUMAN; ORGAN WEIGHT; PENIS GLANS; PRIORITY JOURNAL; PROSTATE VENTRAL LOBE; RAT; SEMINAL PLASMA; SEMINAL VESICLE; TOXICITY TESTING; UTERUS WEIGHT;

ANIMALIA; GLANS;

EID: 0035717798     PISSN: 03405761     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00204-001-0296-4     Document Type: Article

References (10)

1. The peripubertal male rat assay as an alternative to the Hershberger castrated male rat assay for the detection of anti-androgen, oestrogen and metabolic modulators
2. The estrogen receptor relative binding affinities of 188 natural and xenochemicals: Structural diversity of ligands
3. Induction of cytochrome F450 isozymes in rat liver by methyl n-alkyl ketones and n-alkylbenzenes. Effects of hydrophobicity of inducers on inducibility of cytochrome F450
4. A variety of environmentally persistent chemicals, including some phthalate plasticizers, are weakly estrogenic
5. Functional toxicology: A new approach to detect functionally active xenobiotics
6. Estrogens in the environment: Global health implications
7. Estrogenic activities of 517 chemicals by yeast two-hybrid assay
8. Comparison of reproductive tissue weights in the enhanced Hershberger assay of 17α-methyltestosterone between peripubertal and castrated rats
9. Comparison of reporter gene assay and immature rat uterotrophic assay of twenty-three chemicals