Mouse melanoma cell migration is dependent on production of reactive oxygen species under normoxia condition

Biomolecules and Therapeutics

Volumn 20, Issue 2, 2012, Pages 165-170

  Im, Yun Sun ^a   Ryu, Yun Kyoung ^a   Moon, Eun Yi ^a  

^a Sejong University   (South Korea)

Author keywords

Cell migration; ERK; N acetylcysteine; Reactive oxygen species; Tumor growth

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ACETYLCYSTEINE; MITOGEN ACTIVATED PROTEIN KINASE; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ARTICLE; CANCER INHIBITION; CELL DENSITY; CELL MIGRATION; CELL SURVIVAL; CONTROLLED STUDY; DRUG MECHANISM; DRUG RESPONSE; IN VITRO STUDY; IN VIVO STUDY; MELANOMA CELL; MIGRATION INHIBITION; MOUSE; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT; TUMOR VOLUME; WOUND HEALING;

EID: 84862648657     PISSN: 19769148     EISSN: 20054483     Source Type: Journal    
DOI: 10.4062/biomolther.2012.20.2.165     Document Type: Article

References (33)

1. Aghajanian, A., Wittchen, E. S., Campbell, S. L. and Burridge, K. (2009) Direct activation of RhoA by reactive oxygen species requires a redox-sensitive motif. PLoS One 4, e8045.
2. Borisy, G. G. and Svitkina, T. M. (2000) Actin machinery: pushing the envelope. Curr. Opin. Cell Biol. 12, 104-112.
3. Cheng, G. C., Schulze, P. C., Lee, R. T., Sylvan, J., Zetter, B. R. and Huang, H. (2004) Oxidative stress and thioredoxin-interacting protein promote intravasation of melanoma cells. Exp. Cell Res. 300, 297-307.
4. Chetram, M. A., Don-Salu-Hewage, A. S. and Hinton, C. V. (2011) ROS enhances CXCR4-mediated functions through inactivation of PTEN in prostate cancer cells. Biochem. Biophys. Res. Commun. 410, 195-200.
5. Denizot, F. and Lang, R. (1986) Rapid colorimetric assay for cell growth and survival. Modifications to the tetrazolium dye procedure giving improved sensitivity and reliability. J. Immunol. Methods. 89, 271-277.
6. Finkel, T. (2003) Oxidant signals and oxidative stress. Curr. Opin. Cell Biol. 15, 247-254.
7. Folkman, J. (1990) What is the evidence that tumors are angiogenesis dependent? J. Natl. Cancer Inst. 82, 4-6.
8. Han, Y. H., Kwon, J. H., Yu, D. Y. and Moon, E. Y. (2006) Inhibitory effect of peroxiredoxin II (Prx II) on Ras-ERK-NFkappaB pathway in mouse embryonic fibroblast (MEF) senescence. Free Radic. Res. 40, 1182-1189.
9. Jiang, B. H., Liu, L. Z., Schafer, R., Flynn, D. C. and Barnett, J. B. (2006) A novel role for 3, 4-dichloropropionanilide (DCPA) in the inhibition of prostate cancer cell migration, proliferation, and hypoxiainducible factor 1alpha expression. BMC. Cancer 6, 204.
10. Kim, H. S. (2009) Reactive oxygen species-induced expression of B cell activating factor (BAFF) is independent of toll-like receptor 4 and myeloid differentiation primary response gene 88. Biomol. Ther. 17, 144-150.
11. Kim, J. S., Huang, T. Y. and Bokoch, G. M. (2009) Reactive oxygen species regulate a slingshot-cofilin activation pathway. Mol. Biol. Cell. 20, 2650-2660.
12. Lauffenburger, D. A. and Horwitz, A. F. (1996) Cell migration: a physically integrated molecular process. Cell 84, 359-369.
13. Lee, J., Ishihara, A., Theriot, J. A. and Jacobson, K. (1993) Principles of locomotion for simple-shaped cells. Nature 362, 167-171.
14. Lei, Y., Huang, K., Gao, C., Lau, Q. C., Pan, H., Xie, K., Li, J., Liu, R., Zhang, T., Xie, N., Nai, H. S., Wu, H., Dong, Q., Zhao, X., Nice, E. C., Huang, C. and Wei, Y. (2011) Proteomics identification of ITGB3 as a key regulator in reactive oxygen species-induced migration and invasion of colorectal cancer cells. Mol. Cell Proteomics. 10, M110.005397.
15. Lin, S., Sun, L., Hu, J., Wan, S., Zhao, R., Yuan, S. and Zhang, L. (2009) Chemokine C-X-C motif receptor 6 contributes to cell migration during hypoxia. Cancer Lett. 279, 108-117.
16. Luanpitpongm, S., Talbottm, S. J., Rojanasakulm, Y., Nimmannitm, U., Pongrakhananonm, V., Wangm, L. and Chanvorachote, P. (2010) Regulation of lung cancer cell migration and invasion by reactive oxygen species and caveolin-1. J. Biol. Chem. 285, 38832-38840.
17. Luedde, T. (2010) MicroRNA-151 and its hosting gene FAK (focal adhesion kinase) regulate tumor cell migration and spreading of hepatocellular carcinoma. Hepatology 52, 1164-1166.
18. Maulik, N. and Das, D. K. (2002) Redox signaling in vascular angiogenesis. Free Radic. Biol. Med. 33, 1047-1060.
19. Moon, E. Y. (2008) Serum deprivation enhances apoptoticcell death by increasing mitochondrial enzyme aActivity. Biomol. Ther. 16, 1-8.
20. Moon, E. Y., Han, Y. H., Lee, D. S., Han, Y. M. and Yu, D. Y. (2004) Reactive oxygen species induced by the deletion of peroxiredoxin II (PrxII) increases the number of thymocytes resulting in the enlargement of PrxII-null thymus. Eur. J. Immunol. 34, 2119-2128.
21. Moon, E. Y., Im, Y. S., Ryu, Y. K. and Kang, J. H. (2010) Actin-sequestering protein, thymosin beta-4, is a novel hypoxia responsive regulator. Clin. Exp. Metastasis. 27, 601-609.
22. Moon, E. Y., Lee, J. H., Lee, J. W., Song, J. H. and Pyo, S. (2011) ROS/Epac1-mediated Rap1/NF-kappaB activation is required for the expression of BAFF in Raw264.7 murine macrophages. Cell Signal 23, 1479-1488.
23. Oh, J. H., Ryu, Y. K., Lim, J. S. and Moon, E. Y. (2010) Hypoxia induces paclitaxel-resistance through ROS production. Biomolecules & Therapeutics. 18, 145-151.
24. Oh, J. M. and Moon, E. Y. (2010) Actin-sequestering protein, thymosin beta-4, induces paclitaxel resistance through ROS/HIF-1alpha stabilization in HeLa human cervical tumor cells. Life Sci. 87, 286-293.
25. Park, S. Y., Jeong, K. J., Lee, J., Yoon, D. S., Choi, W. S., Kim, Y. K., Han, J. W., Kim, Y. M., Kim, B. K. and Lee, H. Y. (2007) Hypoxia enhances LPA-induced HIF-1alpha and VEGF expression: their inhibition by resveratrol. Cancer Lett. 258, 63-69.
26. Rhee, S. G., Bae, Y. S., Lee, S. R. and Kwon, J. (2000) Hydrogen peroxide: a key messenger that modulates protein phosphorylation through cysteine oxidation. Sci. STKE. 2000, pe1.
27. Ryu, Y. K., Im, Y. S. and Moon, E. Y. (2010) Cooperation of actin-sequestering protein, thymosin β-4 and hypoxia inducible factor-1α in tumor cell migration. Oncol. Rep. 24, 1389-1394.
28. Shim, H., Shim, E., Lee, H., Hahn, J., Kang, D., Lee, Y. S. and Jeoung, D. (2006) CAGE, a novel cancer/testis antigen gene, promotes cell motility by activation ERK and p38 MAPK and downregulating ROS. Mol. Cells 21, 367-375.
29. Singer, S. J. and Kupfer, A. (1986) The directed migration of eukaryotic cells. Annu. Rev. Cell Biol. 2, 337-365.
30. Tobar, N., Guerrero, J., Smith, P. C. and Martínez, J. (2010) NOX4- dependent ROS production by stromal mammary cells modulates epithelial MCF-7 cell migration. Br. J. Cancer 103, 1040-1047.
31. Tonomura, N., McLaughlin, K., Grimm, L., Goldsby, R. A. and Osborne, B. A. (2003) Glucocorticoid-induced apoptosis of thymocytes: requirement of proteasome-dependent mitochondrial activity. J. Immunol. 170, 2469-2478.
32. Webb, D. J., Parsons, J. T. and Horwitz, A. F. (2002) Adhesion assembly, disassembly and turnover in migrating cells -- over and over and over again. Nat. Cell Biol. 4, E97-100.
33. Welch, M. D., Iwamatsu, A. and Mitchison, T. J. (1997) Actin polymerization is induced by Arp2/3 protein complex at the surface of Listeria monocytogenes. Nature 385, 265-269.