Possible involvement of Sphingosine-1-phosphate/Gi/RhoA pathways in adherence of eosinophils to pulmonary endothelium

Allergology International

Volumn 61, Issue 2, 2012, Pages 283-293

  Sashio, Toyokazu ^a   Kume, Hiroaki ^b   Takeda, Naoya ^a   Asano, Toshiaki ^a   Tsuji, Seita ^a   Kondo, Masashi ^a   Hasegawa, Yoshinori ^a   Shimokata, Kaoru ^a  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b KINKI UNIVERSITY SCHOOL OF MEDICINE   (Japan)

Author keywords

Asthma; Eosinophils; Lipid mediators; Pertussis toxin sensitive G protein; Rho kinase; Small G protein; VCAM 1; Y 27632

Indexed keywords

4 (1 AMINOETHYL) N (4 PYRIDYL)CYCLOHEXANECARBOXAMIDE; EXOENZYME C3; GGTI 286; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; INTERCELLULAR ADHESION MOLECULE 1; MESSENGER RNA; PROTEIN INHIBITOR; RHOA GUANINE NUCLEOTIDE BINDING PROTEIN; SPHINGOSINE 1 PHOSPHATE; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1;

ADENOSINE DIPHOSPHATE RIBOSYLATION; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENDOTHELIUM CELL; ENZYME ACTIVATION; EOSINOPHIL ADHERENCE; HUMAN; HUMAN CELL; LEUKOCYTE ADHERENCE; LUNG ENDOTHELIUM; PRIORITY JOURNAL; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

EID: 84862647052     PISSN: 13238930     EISSN: 14401592     Source Type: Journal    
DOI: 10.2332/allergolint.10-OA-0299     Document Type: Article

References (38)

1. Jolly PS, Rosenfeldt HM, Milstien S, Spiegel S. The roles of sphingosine-1-phosphate in asthma. Mol Immunol 2002;38:1239-45.
2. Ammit AJ, Hastie AT, Edsall LC et al. Sphingosine 1-phosphate modulates human airway smooth muscle cell functions that promote inflammation and airway remodeling in asthma. FASEB J 2001;15:1212-4.
3. Roviezzo F, Del Galdo F, Abbate G et al. Human eosinophil chemotaxis and selective in vivo recruitment by sphingosine 1-phosphate. Proc Natl Acad Sci 2004;101: 11170-5.
4. Nishimura T, Nishimura Y, Okada T et al. Inhibition of sphingosine kinase inhibitor attenuates airway inflammation in asthmatic mouse model. Am J Physiol Lung Cell Mol Physiol 2008;294:L1085-93.
5. Rosenfeldt HM, Amrani Y, Watterson KR, Murthy KS, Panettieri RA Jr, Spiegel S. Sphingosine-1-phospahte stimulates contraction of human airway smooth muscle. FASEB J 2003;17:1789-99.
6. Kume H, Takeda N, Oguma T et al. Sphingosine 1-phosphate causes airway hyper-reactivity by Rhomediated myosin phosphatase inactivation. J Pharmacol Exp Ther 2007;320:766-73.
7. Roviezzo F, Di Lorenzo A, Bucci M et al. Sphingosine-1-phosphate/sphingosine kinase pathway is involved in mouse airway hyperresponsiveness. Am J Respir Cell Mol Biol 2007;36:757-62.
8. Uhlig S, Gulbins E. Sphingolipids in the lung. Am J Respir Crit Care Med 2008;178:1000-14.
9. Nishiyama O, Kume H, Kondo M, Ito Y, Ito M, Yamaki K. Role of lysophosphatidylcholine in eosinophil infiltration and resistance in airways. Clin Exp Pharmacol Physiol 2004;31:179-84.
10. Kume N, Cybulsky MI, Gimbrone MA Jr. Lysophosphatidylcholine, a component of atherogenic lipoproteins, induces mononuclear leukocyte adhesion molecules in cultured human and rabbit arterial endothelial cells. J Clin Invest 1992;90:1138-44.
11. Vadas MA, Gamble JR. Endothelial adhesion molecules in atherogenesis. A concerto or a solo? Circ Res 1996;79: 1216-7.
12. Van Aelst L, D'Souza-Schorey C. Rho GTPase and signaling networks. Genes Dev 1997;11:2295-322.
13. Kaibuchi K, Kuroda S, Amano M. Regulation of the cytoskeleton and cell adhesion by the Rho family GTPaes in mammalian cells. Annu Rev Biochem 1996;68:459-86.
14. Taki F, Kume H, Kobayashi T, Ohta H, Aratake H, Shimokata K. Effects of Rho-kinase inactivation on eosinophilia and hyper-reactivity in murine airways by allergen challenges. Clin Exp Allergy 2007;37:599-607.
15. 2+ entry by Rhokinase in tracheal smooth muscle. Am J Respir Cell Mol Biol 2002;26:491-8.
16. 2+ influx and Rho-kinase. Eur J Pharmacol 2007;556:151-6.
17. 2α -induced contraction in airway smooth muscle. Clin Exp Allergy 2009;39: 236-45.
18. 2+ sensitization in tracheal smooth muscle. Am J Respir Cell Mol Biol 2001;25:291-8.
19. 2+ sensitization in tracheal smooth muscle. Clin Exp Allergy 2008;38:135-44.
20. 2+ sensitization in extracellular adenosine triphosphate-induced hyperresponsiveness in airway smooth muscle. Clin Exp Allergy 2007;37:893-900.
21. Takeda N, Kondo M, Ito S, Ito Y, Shimokata K, Kume H. Role of RhoA inactivation in reduced cell proliferation of human airway smooth muscle by simvastatin. Am J Respir Cell Mol Biol 2006;35:722-9.
22. Izumi T, Kishimoto S, Takano T et al. Expression of human platelet-activating factor receptor gene in EoL-1 cells following butyrate-induced differentiation. Biochem J 1995;305:829-35.
23. Yamazaki R, Hatano H, Aiyama R, Matsuzaki T, Hashimoto S, Yokokura T. Diarylheptanoids suppress expression of leukocyte adhesion molecules on human vascular endothelial cells. Eur J Pharmacol 2000;404:375-85.
24. Shimamura K, Takashiro Y, Akiyama N, Hirabayashi T, Murayama T. Expression of adhesion molecules by sphingosine 1-phosphate and histamine in endothelial cells. Eur J Pharmacol 2004;486:141-50.
25. Kimura T, Tomura H, Mogi C et al. Sphingosine 1-phosphate receptors mediate stimulatory and inhibitory signalings for expression of adhesion molecules in endothelial cells. Cell Signal 2006;18:841-50.
26. Jolly PS, Bektas M, Olivera A et al. Transactivation of sphingosine-1-phosphate receptors by FcepsilonRI triggering is required for normal mast cell degranulation and chemotaxis. J ExpMed 2004;199:959-70.
27. Wheeler AP, Ridley AJ. Why three Rho proteins? RhoA, RhoB, RhoC, and cellmotility. Exp Cell Res 2004;301:43-9.
28. Seye CI, Yu N, Jain R et al. The P2Y2 nucleotide receptor mediates UTP-induced vascular cell adhesion molecule-1 expression in coronary artery endothelial cells. J Biol Chem 2003;278:24960-5.
29. Anwar KN, Fazal F, Malik AB, Rahman A. RhoA/Rhoassociated kinase pathway selectively regulates thrombininduced intercellular adhesion molecule-1 expression in endothelial cells via activation of I kappa B kinase beta and phosphorylation of RelA/p65. J Immunol 2004;173: 6965-72.
30. Uehata M, Ishizaki T, Satoh H et al. Calcium sensitization of smooth muscle mediated by a Rho-associated protein kinase in hypertension. Natute 1997;389:990-4.
31. Ghisdal P, Vandenberg G, Morel N. Rho-dependent kinase is involved in agonist-activated calcium entry in rat arteries. J Physiol 2003;551:855-67.
32. Spiegel S, Milstien S. Sphingosine-1-phosphate: an enigmatic signalling lipid. Nat Rev Mol Cell Biol 2003;4:397-407.
33. Kume H, Kotlikoff MI. Muscarinic inhibition of single KCa channels in smooth muscle cells by a pertussissensitive G protein. Am J Physiol 1991;261:C1204-9.
34. Taha TA, Argraves KM, Obeid LM. Sphingosine-1-phosphate receptors: receptor specificity versus functional redundancy. Biochim Biophys Acta 2004;1682:48-55.
35. Lee H, Lin CI, Liao JJ et al. Lysophospholipids increase ICAM-1 expression in HUVEC through a Gi-and NF-kappaB-dependent mechanism. Am J Physiol Cell Physiol 2004;287:C1657-66.
36. Takuwa Y, Okamoto Y, Yoshioka K, Takuwa N. Sphingosine-1-phosphate signaling and biological activities in the cardiovascular system. Biochim Biophys Acta 2008;1781:483-8.
37. Kume H. RhoA/Rho-kinase as a therapeutic target in asthma. Curr Med Chem 2008;15:2876-85.
38. Schaafsma D, Gosens R, Zaagsma J, Halayko AJ, Meurs H. Rho kinase inhibitors: a novel therapeutical intervention in asthma? Eur J Pharmacol 2008;585:398-406.