Comparative evaluation of particle properties, formation of reactive oxygen species and genotoxic potential of tungsten carbide based nanoparticles in vitro

Journal of Hazardous Materials

Volumn 227-228, Issue , 2012, Pages 418-426

  Kühnel, Dana ^a   Scheffler, Katja ^a,b   Wellner, Peggy ^a   Meißner, Tobias ^c   Potthoff, Annegret ^c   Busch, Wibke ^a   Springer, Armin ^d   Schirmer, Kristin ^e,f,g  

^a HELMHOLTZ CENTRE FOR ENVIRONMENTAL RESEARCH UFZ   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c FRAUNHOFER INSTITUTE FOR CERAMIC TECHNOLOGIES AND SYSTEMS   (Germany)

^d UNIVERSITY HOSPITAL CARL GUSTAV CARUS   (Germany)

^e SWISS FEDERAL INSTITUTE OF AQUATIC SCIENCE AND TECHNOLOGY   (Switzerland)

^f EPFL   (Switzerland)

^g ETH ZURICH   (Switzerland)

Author keywords

Characterization; DNA damage; Micronucleus formation; Nanoparticle properties; Reactive oxygen species (ROS)

Indexed keywords

COBALT CONTENT; COMPARATIVE EVALUATIONS; CRYSTALLINE STRUCTURE; CYTOTOXIC; DNA DAMAGES; GENOTOXIC; HARD METALS; IN-VITRO; MAMMALIAN CELLS; MICRONUCLEUS FORMATION; PARTICLE PROPERTIES; REACTIVE OXYGEN SPECIES; SURFACE AREA;

CHARACTERIZATION; COBALT; NANOPARTICLES; OXYGEN; TUNGSTEN;

TUNGSTEN CARBIDE;

COBALT; NANOPARTICLE; REACTIVE OXYGEN METABOLITE; TUNGSTEN CARBIDE; TUNGSTEN DERIVATIVE; UNCLASSIFIED DRUG;

COBALT; COMPARATIVE STUDY; CRYSTAL STRUCTURE; CYTOLOGY; GENOTOXICITY; MAMMAL; OXYGEN; TOXICITY TEST; TOXICOLOGY; TUNGSTEN;

ARTICLE; CELL CULTURE; CELL VIABILITY; COMPARATIVE STUDY; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; CRYSTAL STRUCTURE; DISSOLUTION; EVALUATION; GENOTOXICITY; HUMAN; HUMAN CELL; MICRONUCLEUS; SURFACE PROPERTY; TOXICITY TESTING; ZETA POTENTIAL;

CELL LINE; CELL SURVIVAL; COBALT; HUMANS; METAL NANOPARTICLES; MICRONUCLEUS TESTS; REACTIVE OXYGEN SPECIES; SURFACE PROPERTIES; TUNGSTEN COMPOUNDS;

MAMMALIA;

EID: 84862640759     PISSN: 03043894     EISSN: 18733336     Source Type: Journal    
DOI: 10.1016/j.jhazmat.2012.04.070     Document Type: Article

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