Massive transfusion: An evidence-based review of recent developments

Archives of Surgery

Volumn 147, Issue 6, 2012, Pages 563-571

  Neal, Matthew D ^a   Marsh, Alyce ^c   Marino, Ryan ^c   Kautza, Benjamin ^a   Raval, Jay S ^b   Forsythe, Raquel M ^a   Marshall, Gary T ^a   Sperry, Jason L ^a  

^a PRESBYTERIAN UNIVERSITY HOSPITAL   (United States)

^b UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

^c UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD CLOTTING FACTOR 5A; FRESH FROZEN PLASMA; RECOMBINANT BLOOD CLOTTING FACTOR 7A; TRANEXAMIC ACID;

ACIDOSIS; BLEEDING; BLOOD CLOTTING DISORDER; BLOOD TRANSFUSION; CRYOPRECIPITATE; DRUG FATALITY; HEMOPHILIA; HUMAN; HYPOTHERMIA; MEDLINE; META ANALYSIS (TOPIC); POSTPARTUM HEMORRHAGE; PRIORITY JOURNAL; RANDOMIZED CONTROLLED TRIAL (TOPIC); REVIEW; SYSTEMATIC REVIEW (TOPIC); THROMBOCYTE TRANSFUSION; THROMBOELASTOGRAPHY; THROMBOSIS;

ANTIFIBRINOLYTIC AGENTS; BLOOD TRANSFUSION; CLINICAL PROTOCOLS; FACTOR VIIA; HUMANS; PLASMA; PLATELET TRANSFUSION; RESUSCITATION; TRANEXAMIC ACID;

EID: 84862639920     PISSN: 00040010     EISSN: 15383644     Source Type: Journal    
DOI: 10.1001/archsurg.2011.2212     Document Type: Review

References (52)

1. Nunez TC, Voskresensky IV, Dossett LA, Shinall R, Dutton WD, Cotton BA. Early prediction of massive transfusion in trauma: simple as ABC (Assessment of Blood Consumption)? J Trauma. 2009;66(2):346-352.
2. Yucel N, Lefering R, Maegele M, et al. Trauma Associated Severe Hemorrhage (TASH) score: probability of mass transfusion as surrogate for life-threatening hemorrhage after multiple trauma. J Trauma. 2006;60(6):1228-1236.
3. Stanworth SJ, Morris TP, Gaarder C, et al. Reappraising the concept of massive transfusion in trauma. Crit Care. 2010;14(6):R239.
4. Nunez TC, Dutton WD, May AK, Holcomb JB, Young PP, Cotton BA. Emergency department blood transfusion predicts early massive transfusion and early blood component requirement. Transfusion. 2010;50(9):1914-1920.
5. Cotton BA, Gunter OL, Isbell J, et al. Damage control hematology: the impact of atraumaexsanguinationprotocolonsurvivalandblood product utilization. J Trauma. 2008;64(5):1177-1183.
6. Gonzalez EA, Moore FA, Holcomb JB, et al. Fresh frozen plasma should be given earlier to patients requiring massive transfusion. J Trauma. 2007;62(1):112-119.
7. Riskin DJ, Tsai TC, Riskin L, et al. Massive transfusion protocols: the role of aggressive resuscitation versus product ratio in mortality reduction. J Am Coll Surg. 2009;209(2):198-205.
8. O'Keeffe T, Refaai M, Tchorz K, Forestner JE, Sarode R. A massive transfusion protocol to decrease blood component use and costs. Arch Surg. 2008;143(7):686-691.
9. Lier H, Böttiger BW, Hinkelbein J, Krep H, Bernhard M. Coagulation management in multiple trauma: a systematic review. Intensive Care Med. 2011;37(4):572-582.
10. Cushing M, Shaz BH. Blood transfusion in trauma patients: unresolved questions. Minerva Anestesiol. 2011;77(3):349-359.
11. Rajasekhar A, Gowing R, Zarychanski R, et al. Survival of trauma patients after massive red blood cell transfusion using a high or low red blood cell to plasma transfusion ratio. Crit Care Med. 2011;39(6):1507-1513.
12. Borgman MA, Spinella PC, Holcomb JB, et al. The effect of FFP:RBC ratio on morbidity and mortality in trauma patients based on transfusion prediction score. Vox Sang. 2011;101(1):44-54.
13. Magnotti LJ, Zarzaur BL, Fischer PE, et al. Improved survival after hemostatic resuscitation: does the emperor have no clothes? J Trauma. 2011;70(1):97-102.
14. de Biasi AR, Stansbury LG, Dutton RP, Stein DM, Scalea TM, Hess JR. Blood product use in trauma resuscitation: plasma deficit versus plasma ratio as predictors of mortality in trauma (CME). Transfusion. 2011;51(9):1925-1932.
15. Phan HH, Wisner DH. Should we increase the ratio of plasma/platelets to red blood cells in massive transfusion: what is the evidence? Vox Sang. 2010;98(3, pt 2):395-402.
16. Roback JD, Caldwell S, Carson J, et al; American Association for the Study of Liver; American Academy of Pediatrics; United States Army; American Society of Anesthesiology; American Society of Hematology. Evidence-based practice guidelines for plasma transfusion. Transfusion. 2010;50(6):1227-1239.
17. Snyder CW, Weinberg JA, McGwin G Jr, et al. The relationship of blood product ratio to mortality: survival benefit or survival bias? J Trauma. 2009;66(2):358-364.
18. Teixeira PG, Inaba K, Shulman I, et al. Impact of plasma transfusion in massively transfused trauma patients. J Trauma. 2009;66(3):693-697.
19. Duchesne JC, Hunt JP, Wahl G, et al. Review of current blood transfusions strategies in amature level I trauma center: were we wrong for the last 60 years? J Trauma. 2008;65(2):272-278.
20. Kashuk JL, Moore EE, Johnson JL, et al. Postinjury life-threatening coagulopathy: is 1:1 fresh frozen plasma:packed red blood cells the answer? J Trauma. 2008;65(2):261-271.
21. Maegele M, Lefering R, Paffrath T, Tjardes T, Simanski C, Bouillon B; Working Group on Polytrauma of the German Society of Trauma Surgery (DGU). Red-blood-cell to plasma ratios transfused during massive transfusion are associated with mortality in severe multiple injury: a retrospective analysis from the Trauma Registry of the Deutsche Gesellschaft für Unfallchirurgie. Vox Sang. 2008;95(2):112-119.
22. Scalea TM, Bochicchio KM, Lumpkins K, et al. Early aggressive use of fresh frozen plasma does not improve outcome in critically injured trauma patients. Ann Surg. 2008;248(4):578-584.
23. Sperry JL, Ochoa JB, Gunn SR, et al; Inflammation the Host Response to Injury Investigators. An FFP:PRBC transfusion ratio >/=1:1.5 is associated with a lower risk of mortality after massive transfusion. J Trauma. 2008;65(5):986-993.
24. Borgman MA, Spinella PC, Perkins JG, et al. The ratio of blood products transfused affects mortality in patients receiving massive transfusions at a combat support hospital. J Trauma. 2007;63(4):805-813.
25. Zink KA, Sambasivan CN, Holcomb JB, Chisholm G, Schreiber MA. A high ratio of plasma and platelets to packed red blood cells in the first 6 hours of massive transfusion improves outcomes in a large multicenter study. Am J Surg. 2009;197(5):565-570.
26. Holcomb JB, Wade CE, Michalek JE, et al. Increased plasma and platelet to red blood cell ratios improve outcome in 466 massively transfused civilian trauma patients. Ann Surg. 2008;248(3):447-458.
27. Shaz BH, Dente CJ, Nicholas J, et al. Increased number of coagulation products in relationship to red blood cell products transfused improves mortality in trauma patients. Transfusion. 2010;50(2):493-500.
28. Perkins JG, Cap AP, Spinella PC, et al; 31st Combat Support Hospital Research Group. Comparison of platelet transfusion as fresh whole blood versus apheresis platelets for massively transfused combat trauma patients (CME). Transfusion. 2011;51(2):242-252.
29. Inaba K, Lustenberger T, Rhee P, et al. The impact of platelet transfusion inmassively transfused trauma patients. J Am Coll Surg. 2010;211(5):573-579.
30. Fenger-Eriksen C, Lindberg-Larsen M, Christensen AQ, Ingerslev J, Sørensen B. Fibrinogen concentrate substitution therapy in patients with massive haemorrhage and low plasma fibrinogen concentrations. Br J Anaesth. 2008;101(6):769-773.
31. Stinger HK, Spinella PC, Perkins JG, et al. The ratio of fibrinogen to red cells transfused affects survival in casualties receiving massive transfusions at an army combat support hospital. J Trauma. 2008;64(2)(suppl): S79-S85.
32. Dutton RP, Parr M, Tortella BJ, et al; CONTROL Study Group. Recombinant activated factor VII safety in trauma patients: results from the CONTROL trial. J Trauma. 2011;71(1):12-19.
33. Kalina M, Tinkoff G, Fulda G. Massive postpartum hemorrhage: recombinant factor VIIa use is safe but not effective. Del Med J. 2011;83(4):109-113.
34. Wade CE, Eastridge BJ, Jones JA, et al. Use of recombinant factor VIIa in US military casualties for a five-year period. J Trauma. 2010;69(2):353-359.
35. Masud F, Bostan F, Chi E, et al. Recombinant factor VIIa treatment of severe bleeding in cardiac surgery patients: a retrospective analysis of dosing, efficacy, and safety outcomes. J Cardiothorac Vasc Anesth. 2009;23(1):28-33.
36. Duchesne JC, Mathew KA, Marr AB, Pinsky MR, Barbeau JM, McSwain NE. Current evidence-based guidelines for factor VIIa use in trauma: the good, the bad, and the ugly. Am Surg. 2008;74(12):1159-1165.
37. Moltzan CJ, Anderson DA, Callum J, et al. The evidence for the use of recombinant factor VIIa in massive bleeding: development of a transfusion policy framework. Transfus Med. 2008;18(2):112-120.
38. Spinella PC, Perkins JG, McLaughlin DF, et al. The effect of recombinant activated factor VII on mortality in combat-related casualties with severe trauma and massive transfusion. J Trauma. 2008;64(2):286-294.
39. Perkins JG, Schreiber MA, Wade CE, Holcomb JB. Early versus late recombinant factor VIIa in combat trauma patients requiring massive transfusion. J Trauma. 2007;62(5):1095-1101.
40. Rizoli SB, Boffard KD, Riou B, et al; NovoSeven Trauma Study Group. Recombinant activated factor VII as an adjunctive therapy for bleeding control in severe trauma patients with coagulopathy: subgroup analysis from two randomized trials. Crit Care. 2006;10(6):R178.
41. Rizoli SB, Nascimento B Jr, Osman F, et al. Recombinant activated coagulation factor VII and bleeding trauma patients. J Trauma. 2006;61(6):1419-1425.
42. Boffard KD, Riou B, Warren B, et al; NovoSeven Trauma Study Group. Recombinant factor VIIa as adjunctive therapy for bleeding control in severely injured trauma patients: two parallel randomized, placebo-controlled, double-blind clinical trials. J Trauma. 2005;59(1):8-18.
43. Fenger-Eriksen C, Jensen TM, Kristensen BS, et al. Fibrinogen substitution improves whole blood clot firmness after dilution with hydroxyethyl starch in bleeding patients undergoing radical cystectomy: a randomized, placebo-controlled clinical trial. J Thromb Haemost. 2009;7(5):795-802.
44. Nienaber U, Innerhofer P, Westermann I, et al. The impact of fresh frozen plasma vs coagulation factor concentrates on morbidity and mortality in trauma-associated haemorrhage and massive transfusion. Injury. 2011;42(7):697-701.
45. Roberts I, Shakur H, Afolabi A, et al. The importance of early treatment with tranexamic acid in bleeding trauma patients: an exploratory analysis of the CRASH-2 randomised controlled trial. Lancet. 2011;377(9771):1096-1101.
46. Wang G, Xie G, Jiang T, et al. Tranexamic acid reduces blood loss after off-pump coronary surgery: a prospective, randomized, double-blind, placebo-controlled study [published online July 7, 2011]. Anesth Analg. .
47. Novikova N, Hofmeyr GJ. Tranexamic acid for preventing postpartum haemorrhage. Cochrane Database Syst Rev. 2010;(7):CD007872.
48. Bokesch PM,Szabo G, Wojdyga R, et al.Aphase 2 prospective, randomized, double-blind trial comparing the effects of tranexamic acid with ecallantide on blood loss fromhigh-riskcardiacsurgerywithcardiopulmonarybypass(CONSERV-2Trial) [published online July 1, 2011]. J Thorac Cardiovasc Surg. 2011.
49. Guerriero C, Cairns J, Perel P, Shakur H, Roberts I; CRASH-2 trial collaborators. Cost-effectiveness analysis of administering tranexamic acid to bleeding trauma patients using evidence from the CRASH-2 trial. PLoS One. 2011;6(5):e18987.
50. Afshari A, Wikkelsø A, Brok J, Møller AM, Wetterslev J. Thromboelastography (TEG) or thromboelastometry (ROTEM) to monitor haemotherapy versus usual care in patients with massive transfusion. Cochrane Database Syst Rev. 2011;(3):CD007871.
51. Gonzalez E, Pieracci FM, Moore EE, Kashuk JL. Coagulation abnormalities in the trauma patient: the role of point-of-care thromboelastography. Semin Thromb Hemost. 2010;36(7):723-737.
52. Leemann H, Lustenberger T, Talving P, et al. The role of rotation thromboelastometry in early prediction of massive transfusion. J Trauma. 2010;69(6):1403-1409.