메뉴 건너뛰기




Volumn 17, Issue 1, 2012, Pages 99-107

A Cell-Based High-Throughput Screening Assay to Measure Cellular Histone H3 Lys27 Trimethylation with a Modified Dissociation-Enhanced Lanthanide Fluorescent Immunoassay

Author keywords

[No Author keywords available]

Indexed keywords

ENZYME INHIBITOR; HISTONE; HISTONE LYSINE METHYLTRANSFERASE; HISTONE METHYLTRANSFERASE; LANTHANIDE; LYSINE;

EID: 84862637665     PISSN: 10870571     EISSN: 1552454X     Source Type: Journal    
DOI: 10.1177/1087057111422378     Document Type: Article
Times cited : (9)

References (23)
  • 1
    • 0033529565 scopus 로고    scopus 로고
    • Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome
    • Kornberg R. D. Lorch Y. Twenty-Five Years of the Nucleosome, Fundamental Particle of the Eukaryote Chromosome. Cell 1999, 98, 285–294.
    • (1999) Cell , vol.98 , pp. 285-294
    • Kornberg, R.D.1    Lorch, Y.2
  • 3
    • 33745632390 scopus 로고    scopus 로고
    • The Epigenetic Magic of Histone Lysine Methylation
    • Jenuwein T. The Epigenetic Magic of Histone Lysine Methylation. FEBS J. 2006, 273, 3121–3135.
    • (2006) FEBS J. , vol.273 , pp. 3121-3135
    • Jenuwein, T.1
  • 4
    • 0030271391 scopus 로고    scopus 로고
    • Histone Acetylation and Chromatin Assembly: A Single Escort, Multiple Dances?
    • Roth S. Y. Allis C. D. Histone Acetylation and Chromatin Assembly: A Single Escort, Multiple Dances? Cell 1996, 87, 5–8.
    • (1996) Cell , vol.87 , pp. 5-8
    • Roth, S.Y.1    Allis, C.D.2
  • 5
    • 0035839136 scopus 로고    scopus 로고
    • Translating the Histone Code
    • Jenuwein T. Allis C. D. Translating the Histone Code. Science 2001, 293, 1074–1080.
    • (2001) Science , vol.293 , pp. 1074-1080
    • Jenuwein, T.1    Allis, C.D.2
  • 6
    • 1942503942 scopus 로고    scopus 로고
    • The Functions of E(Z)/EZH2-Mediated Methylation of Lysine 27 in Histone H3
    • Cao R. Zhang Y. The Functions of E(Z)/EZH2-Mediated Methylation of Lysine 27 in Histone H3. Curr. Opin. Genet. Dev. 2004, 14, 155–164.
    • (2004) Curr. Opin. Genet. Dev. , vol.14 , pp. 155-164
    • Cao, R.1    Zhang, Y.2
  • 7
    • 0036340237 scopus 로고    scopus 로고
    • The Core of the Polycomb Repressive Complex Is Compositionally and Functionally Conserved in Flies and Humans
    • Levine S. S. Weiss A. Erdjument-Bromage H. Shao Z. Tempst P. Kingston R. E. The Core of the Polycomb Repressive Complex Is Compositionally and Functionally Conserved in Flies and Humans. Mol. Cell Biol. 2002, 22, 6070–6078.
    • (2002) Mol. Cell Biol. , vol.22 , pp. 6070-6078
    • Levine, S.S.1    Weiss, A.2    Erdjument-Bromage, H.3    Shao, Z.4    Tempst, P.5    Kingston, R.E.6
  • 9
    • 70349469565 scopus 로고    scopus 로고
    • Mechanisms of Polycomb Gene Silencing: Knowns and Unknowns
    • Simon J. A. Kingston R. E. Mechanisms of Polycomb Gene Silencing: Knowns and Unknowns. Nat. Rev. Mol. Cell Biol. 2009, 10, 697–708.
    • (2009) Nat. Rev. Mol. Cell Biol. , vol.10 , pp. 697-708
    • Simon, J.A.1    Kingston, R.E.2
  • 12
    • 77950874502 scopus 로고    scopus 로고
    • Comprehensive Evaluation of the Role of EZH2 in the Growth, Invasion, and Aggression of a Panel of Prostate Cancer Cell Lines
    • Karanikolas B. D. Figueiredo M. L. Wu L. Comprehensive Evaluation of the Role of EZH2 in the Growth, Invasion, and Aggression of a Panel of Prostate Cancer Cell Lines. Prostate 2010, 70, 675–688.
    • (2010) Prostate , vol.70 , pp. 675-688
    • Karanikolas, B.D.1    Figueiredo, M.L.2    Wu, L.3
  • 14
    • 55949136562 scopus 로고    scopus 로고
    • Roles of the EZH2 Histone Methyltransferase in Cancer Epigenetics
    • Simon J. A. Lange C. A. Roles of the EZH2 Histone Methyltransferase in Cancer Epigenetics. Mutat. Res. 2008, 647, 21–29.
    • (2008) Mutat. Res. , vol.647 , pp. 21-29
    • Simon, J.A.1    Lange, C.A.2
  • 15
    • 78650454078 scopus 로고    scopus 로고
    • Coordinated Activities of Wild-Type Plus Mutant EZH2 Drive Tumor-Associated Hypertrimethylation of Lysine 27 on Histone H3 (H3K27) in Human B-cell Lymphomas
    • Sneeringer C. J. Scott M. P. Kuntz K. W. Knutson S. K. Pollock R. M. Richon V. M. Copeland R. A. Coordinated Activities of Wild-Type Plus Mutant EZH2 Drive Tumor-Associated Hypertrimethylation of Lysine 27 on Histone H3 (H3K27) in Human B-cell Lymphomas. Proc. Natl. Acad. Sci. U. S. A. 2010, 107, 20980–20985.
    • (2010) Proc. Natl. Acad. Sci. U. S. A. , vol.107 , pp. 20980-20985
    • Sneeringer, C.J.1    Scott, M.P.2    Kuntz, K.W.3    Knutson, S.K.4    Pollock, R.M.5    Richon, V.M.6    Copeland, R.A.7
  • 19
    • 0013881688 scopus 로고
    • The Acid Extraction of Histones from Calf Thymus Deoxyribonucleoprotein
    • Murray K. The Acid Extraction of Histones from Calf Thymus Deoxyribonucleoprotein. J. Mol. Biol. 1966, 15, 409–419.
    • (1966) J. Mol. Biol. , vol.15 , pp. 409-419
    • Murray, K.1
  • 20
    • 0035499141 scopus 로고    scopus 로고
    • High-Throughput Screening for Identification of Small Molecule Inhibitors of Histone Acetyltransferases Using Scintillating Microplates (FlashPlate)
    • Turlais F. Hardcastle A. Rowlands M. Newbatt Y. Bannister A. Kouzarides T. Workman P. Aherne G. W. High-Throughput Screening for Identification of Small Molecule Inhibitors of Histone Acetyltransferases Using Scintillating Microplates (FlashPlate). Anal. Biochem. 2001, 298, 62–68.
    • (2001) Anal. Biochem. , vol.298 , pp. 62-68
    • Turlais, F.1    Hardcastle, A.2    Rowlands, M.3    Newbatt, Y.4    Bannister, A.5    Kouzarides, T.6    Workman, P.7    Aherne, G.W.8
  • 22
    • 67649371461 scopus 로고    scopus 로고
    • DZNep Is a Global Histone Methylation Inhibitor That Reactivates Developmental Genes Not Silenced by DNA Methylation
    • Miranda T. B. Cortez C. C. Yoo C. B. Liang G. Abe M. Kelly T. K. Marquez V. E. Jones P. A. DZNep Is a Global Histone Methylation Inhibitor That Reactivates Developmental Genes Not Silenced by DNA Methylation. Mol. Cancer Ther. 2009, 8, 1579–1588.
    • (2009) Mol. Cancer Ther. , vol.8 , pp. 1579-1588
    • Miranda, T.B.1    Cortez, C.C.2    Yoo, C.B.3    Liang, G.4    Abe, M.5    Kelly, T.K.6    Marquez, V.E.7    Jones, P.A.8
  • 23
    • 79954793059 scopus 로고    scopus 로고
    • S-Adenosylhomocysteine Hydrolase Inhibition by 3-Deazaneplanocin A Analogues Induces Anti-Cancer Effects in Breast Cancer Cell Lines and Synergy with Both Histone Deacetylase and HER2 Inhibition
    • Hayden A. Johnson P. W. Packham G. Crabb S. J. S-Adenosylhomocysteine Hydrolase Inhibition by 3-Deazaneplanocin A Analogues Induces Anti-Cancer Effects in Breast Cancer Cell Lines and Synergy with Both Histone Deacetylase and HER2 Inhibition. Breast Cancer Res. Treat. 2011, 127, 109–119.
    • (2011) Breast Cancer Res. Treat. , vol.127 , pp. 109-119
    • Hayden, A.1    Johnson, P.W.2    Packham, G.3    Crabb, S.J.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.