The role of transcription factor snail1 in the regulation of hormonal sensitivity of in vitro cultured breast cancer cells

Voprosy Onkologii

Volumn 58, Issue 1, 2012, Pages 71-76

  Andreeva, O E ^a   Scherbakov, A M ^a   Shatskaya, V A ^a   Krasil'nikov, M A ^a  

^a N N BLOKHIN RUSSIAN CANCER RESEARCH CENTER   (Russian Federation)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN; ESTROGEN RECEPTOR; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; TAMOXIFEN; TRANSCRIPTION FACTOR SNAIL; TRANSCRIPTION FACTOR SNAIL1; UNCLASSIFIED DRUG; ANTIESTROGEN; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; SNAIL FAMILY TRANSCRIPTION FACTORS; TRANSCRIPTION FACTOR;

ARTICLE; CANCER CELL CULTURE; CELL INVASION; CELL STRAIN HBL 100; CELL STRAIN MCF 7; CELL STRAIN MCF 7 LS; DRUG MECHANISM; DRUG TARGETING; EPITHELIAL MESENCHYMAL TRANSITION; ESTROGEN RECEPTOR POSITIVE BREAST CANCER; HORMONE RESISTANCE; HORMONE SENSITIVITY; HUMAN; HUMAN CELL; METASTASIS; PROTEIN EXPRESSION; REGULATORY MECHANISM; RNA INTERFERENCE; BREAST TUMOR; CHEMISTRY; FEMALE; GENE EXPRESSION REGULATION; METABOLISM; NEOPLASM; PATHOLOGY; TUMOR CELL CULTURE;

ANTINEOPLASTIC AGENTS, HORMONAL; BREAST NEOPLASMS; ESTROGEN ANTAGONISTS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASMS, HORMONE-DEPENDENT; NF-KAPPA B; RECEPTORS, ESTROGEN; RNA INTERFERENCE; TAMOXIFEN; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED;

EID: 84862620154     PISSN: 05073758     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (21)

1. Arpinò G., De Angelis C., Giuliano M. et al. Molecular mechanism and clinical implications of endocrine therapy resistance in breast cancer // Oncology. - 2009. - Vol. 77 Suool. 1. - P. 23-37.
2. Clarke R., Liu M.C., Bouker K.B. et al. Antiestrogen resistance in breast cancer and the role of estrogen receptor signaling // Oncogene. - 2003. - Vol. 22. - P. 7316-7339.
3. Dhasarathy A., Kajita M., Wade P.A. The transcription factor snail mediates epithelial to mesenchymal transitions by repression of estrogen receptor-alpha // Mol. Endocrinol. - 2007. - Vol. 21. - P. 2907-2918.
4. Fujita N., Kajita M., Taysavang P., Wade P.A. Hormonal regulation of metastasis-associated protein 3 transcription in breast cancer cells // Mol. Endocrinol. - 2004. - Vol. 18. - P. 2937-2949.
5. Haagenson K.K., Wu G.S. The role of MAP kinases and MAP kinase phosphatase-1 in resistance to breast cancer treatment // Cancer Metastasis Rev. - 2010. - Vol. 29. - P. 143-149.
6. Jordan V.C. Targeting antihormone resistance in breast cancer: a simple solution // Ann. Oncol. - 2003. - Vol. 14. - P. 969-970.
7. Kim M.R., Choi H.K., Cho K.B. et al. Involvement of Pin1 induction in epithelial-mesenchymal transition of tamoxifen-resistant breast cancer cells // Cancer Sci. - 2009. - Vol. 100. - P. 1834-1841.
8. Krasil'nikov M.A., Shatskaya V.A., Stavrovskaya A.A. et al. The role of phosphatidylinositol 3-kinase in the regulation of cell response to steroid hormones // Biochim. Biophys. Acta. - 1999. - Vol. 1450. - P. 434-443.
9. Lobanova Y.S., Scherbakov A.M., Shatskaya V.A. et al. NF-kappaB suppression provokes the sensitization of hormone-resistant breast cancer cells to estrogen apoptosis // Mol. Cell. Biochem. - 2009. - Vol. 324. - P. 65-71.
10. Lundgren K., Nordenskjold B., Landberg G. Hypoxia, Snail and incomplete epithelial-mesenchymal transition in breast cancer // Brit. J. Cancer. - 2009. - Vol. 101. - P. 1769-1781.
11. Micalizzi D.S., Farabaugh S.M., Ford H.L. Epithelial-mesenchymal transition in cancer: parallels between normal development and tumor progression // J. Mammary Gland. Biol. Neoplasia. - 2010. - Vol. 15. - P. 117-134.
12. Musgrove E.A., Sutherland R.L. Biological determinants ot endocrine resistance in breast cancer // Nat. Rev. Cancer. - 2009. - Vol. 9. - P. 631-643.
13. Normanno N., Di Maio M., De Maio E. et al. Mechanisms of endocrine resistance and novel therapeutic strategies in breast cancer // Endocrin. Relat. Cancer. - 2005. - Vol. 12 - P. 721-747.
14. Park S.H., Cheung L.W., Wong A.S., Leung P.C. Estrogen regulates Snail and Slug in the down-regulation of E-cadherin and induces metastatic potential of ovarian cancer cells through estrogen receptor alpha // Mol. Endocrinol. - 2008. - Vol. 22. - P. 2085-2098.
15. Reid G., Hubner M.R., Metivier R. et al. Cyclic, proteasome-mediated turnover of unliganded and liganded ERalpha on responsive promoters is an integral feature of estrogen signaling // Mol. Cell. - 2003. - Vol. 11. - P. 695-707.
16. Storci G., Sansone P., Mari S. et al. TNFalpha up-regulates SLUG via the NF-kappaB/HIF1 alpha axis, which imparts breast cancer cells with a stem cell-like phenotype // J. Cell. Physiol. - 2010. - Vol. 225. - P. 682-691.
17. Vincent T., Neve E.P., Johnson J.R. et al. A SNAIL1-SMAD3/4 transcriptional repressor complex promotes TGF-beta mediated epithelial-mesenchymal transition // Nat. Cell. Biol. - 2009. - Vol. 11. - P. 943-950.
18. Wu Y., Zhou B.P. TNF-alpha/NF-kappaB/Snail pathway in cancer cell migration and invasion // Brit. J. Cancer. - 2010. - Vol. 102. - P. 639-644.
19. Yu M., Smolen G.A., Zhang J. et al. A developmentally regulated inducer of EMT, LBX1, contributes to breast cancer progression // Genes Dev. - 2009. - Vol. 23. - P. 1737-1742.