Enhanced anti-serpin antibody activity inhibits autoimmune inflammation in type 1 diabetes

Journal of Immunology

Volumn 188, Issue 12, 2012, Pages 6319-6327

  Czyzyk, Jan ^a   Henegariu, Octavian ^b   Preston Hurlburt, Paula ^b   Baldzizhar, Raman ^a   Fedorchuk, Christine ^a   Esplugues, Enric ^b   Bottomly, Kim ^c   Gorus, Frans K ^d,e   Herold, Kevan ^b   Flavell, Richard A ^a,f  

^a UNIVERSITY OF ROCHESTER MEDICAL CENTER   (United States)

^b YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c WELLESLEY COLLEGE   (United States)

^d DIABETES RESEARCH CENTER   (Belgium)

^e Belgian Diabetes Registry   (Belgium)

^f HOWARD HUGHES MEDICAL INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CD45 ANTIGEN; SERINE PROTEINASE INHIBITOR; SERINE PROTEINASE INHIBITOR ANTIBODY; SERINE PROTEINASE INHIBITOR B13 ANTIBODY; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; ANIMAL CELL; ANIMAL EXPERIMENT; ANTIINFLAMMATORY ACTIVITY; ARTICLE; AUTOIMMUNITY; CD4+ T LYMPHOCYTE; CHILD; CLADISTICS; CONTROLLED STUDY; HUMAN; HUMAN CELL; HUMORAL IMMUNITY; IMMUNE RESPONSE; IMPAIRED GLUCOSE TOLERANCE; INSULIN DEPENDENT DIABETES MELLITUS; LYMPHOCYTE PROLIFERATION; MAJOR CLINICAL STUDY; MOUSE; NONHUMAN; ONSET AGE; PANCREAS ISLET CELL; PRESCHOOL CHILD; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; REMISSION; RISK FACTOR; SCHOOL CHILD; SPLEEN CELL;

ADOLESCENT; ANIMALS; AUTOANTIBODIES; AUTOANTIGENS; BLOTTING, WESTERN; CHILD; CHILD, PRESCHOOL; DIABETES MELLITUS, TYPE 1; HUMANS; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, INBRED NOD; MICE, SCID; SERPINS; TRANSFECTION; YOUNG ADULT;

EID: 84862609224     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1200467     Document Type: Article

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