-
1
-
-
0037180768
-
The immunopathogenesis of sepsis
-
DOI 10.1038/nature01326
-
Cohen, J. 2002. The immunopathogenesis of sepsis. Nature 420: 885-891. (Pubitemid 36019643)
-
(2002)
Nature
, vol.420
, Issue.6917
, pp. 885-891
-
-
Cohen, J.1
-
2
-
-
0038447123
-
Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock
-
DOI 10.1128/CMR.16.3.379-414.2003
-
Van Amersfoort, E. S., T. J. Van Berkel, and J. Kuiper. 2003. Receptors, mediators, and mechanisms involved in bacterial sepsis and septic shock. Clin. Microbiol. Rev. 16: 379-414. (Pubitemid 36871313)
-
(2003)
Clinical Microbiology Reviews
, vol.16
, Issue.3
, pp. 379-414
-
-
Van Amersfoort, E.S.1
Van Berkel, T.J.C.2
Kuiper, J.3
-
4
-
-
0036212849
-
Innate immune recognition
-
DOI 10.1146/annurev.immunol.20.083001.084359
-
Janeway, C. A., Jr., and R. Medzhitov. 2002. Innate immune recognition. Annu. Rev. Immunol. 20: 197-216. (Pubitemid 34293424)
-
(2002)
Annual Review of Immunology
, vol.20
, pp. 197-216
-
-
Janeway Jr., C.A.1
Medzhitov, R.2
-
5
-
-
0035104119
-
LPS induction of gene expression in human monocytes
-
DOI 10.1016/S0898-6568(00)00149-2, PII S0898656800001492
-
Guha, M., and N. Mackman. 2001. LPS induction of gene expression in human monocytes. Cell. Signal. 13: 85-94. (Pubitemid 32222977)
-
(2001)
Cellular Signalling
, vol.13
, Issue.2
, pp. 85-94
-
-
Guha, M.1
Mackman, N.2
-
6
-
-
0025107568
-
Structure and function of lipopolysaccharide binding protein
-
Schumann, R. R., S. R. Leong, G. W. Flaggs, P. W. Gray, S. D. Wright, J. C. Mathison, P. S. Tobias, and R. J. Ulevitch. 1990. Structure and function of lipopolysaccharide binding protein. Science 249: 1429-1431. (Pubitemid 120034117)
-
(1990)
Science
, vol.249
, Issue.4975
, pp. 1429-1431
-
-
Schumann, R.R.1
Leong, S.R.2
Flaggs, G.W.3
Gray, P.W.4
Wright, S.D.5
Mathison, J.C.6
Tobias, P.S.7
Ulevitch, R.J.8
-
7
-
-
0025166114
-
CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein
-
Wright, S. D., R. A. Ramos, P. S. Tobias, R. J. Ulevitch, and J. C. Mathison. 1990. CD14, a receptor for complexes of lipopolysaccharide (LPS) and LPS binding protein. Science 249: 1431-1433.
-
(1990)
Science
, vol.249
, pp. 1431-1433
-
-
Wright, S.D.1
Ramos, R.A.2
Tobias, P.S.3
Ulevitch, R.J.4
Mathison, J.C.5
-
8
-
-
0034292364
-
Cutting edge: Lipopolysaccharide induces physical proximity between CD14 and Toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappaB
-
Jiang, Q., S. Akashi, K. Miyake, and H. R. Petty. 2000. Lipopolysaccharide induces physical proximity between CD14 and toll-like receptor 4 (TLR4) prior to nuclear translocation of NF-kappa B. J. Immunol. 165: 3541-3544. (Pubitemid 32057253)
-
(2000)
Journal of Immunology
, vol.165
, Issue.7
, pp. 3541-3544
-
-
Jiang, Q.1
Akashi, S.2
Miyake, K.3
Petty, H.R.4
-
9
-
-
0035877718
-
Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. Transfer from CD14 to TLR4 and MD-2
-
da Silva Correia, J., K. Soldau, U. Christen, P. S. Tobias, and R. J. Ulevitch. 2001. Lipopolysaccharide is in close proximity to each of the proteins in its membrane receptor complex. transfer from CD14 to TLR4 and MD-2. J. Biol. Chem. 276: 21129-21135.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 21129-21135
-
-
Da Silva Correia, J.1
Soldau, K.2
Christen, U.3
Tobias, P.S.4
Ulevitch, R.J.5
-
11
-
-
0019861825
-
Functional properties of an endothelial cell cofactor for thrombin catalyzed activation of protein C
-
Owen,W. G., and C. T. Esmon. 1981. Functional properties of an endothelial cell cofactor for thrombin-catalyzed activation of protein C. J. Biol. Chem. 256: 5532-5535. (Pubitemid 11035389)
-
(1981)
Journal of Biological Chemistry
, vol.256
, Issue.11
, pp. 5532-5535
-
-
Owen, W.G.1
Esmon, C.T.2
-
12
-
-
0024558370
-
The roles of protein C and thrombomodulin in the regulation of blood coagulation
-
Esmon, C. T. 1989. The roles of protein C and thrombomodulin in the regulation of blood coagulation. J. Biol. Chem. 264: 4743-4746. (Pubitemid 19092874)
-
(1989)
Journal of Biological Chemistry
, vol.264
, Issue.9
, pp. 4743-4746
-
-
Esmon, C.T.1
-
13
-
-
0028876697
-
Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system
-
Healy, A. M., H. B. Rayburn, R. D. Rosenberg, and H. Weiler. 1995. Absence of the blood-clotting regulator thrombomodulin causes embryonic lethality in mice before development of a functional cardiovascular system. Proc. Natl. Acad. Sci. USA 92: 850-854.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 850-854
-
-
Healy, A.M.1
Rayburn, H.B.2
Rosenberg, R.D.3
Weiler, H.4
-
14
-
-
0036719075
-
The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways
-
DOI 10.1084/jem.20020077
-
Conway, E. M., M. Van de Wouwer, S. Pollefeyt, K. Jurk, H. Van Aken, A. De Vriese, J. I. Weitz, H. Weiler, P. W. Hellings, P. Schaeffer, et al. 2002. The lectin-like domain of thrombomodulin confers protection from neutrophil-mediated tissue damage by suppressing adhesion molecule expression via nuclear factor kappaB and mitogen-activated protein kinase pathways. J. Exp. Med. 196: 565-577. (Pubitemid 35024436)
-
(2002)
Journal of Experimental Medicine
, vol.196
, Issue.5
, pp. 565-577
-
-
Conway, E.M.1
Van De, W.M.2
Pollefeyt, S.3
Jurk, K.4
Van Aken, H.5
De Vriese, A.6
Weitz, J.I.7
Weiler, H.8
Hellings, P.W.9
Schaeffer, P.10
Herbert, J.-M.11
Collen, D.12
Theilmeier, G.13
-
15
-
-
0344443722
-
Thrombomodulin-mediated cell adhesion: Involvement of its lectin-like domain
-
Huang, H. C., G. Y. Shi, S. J. Jiang, C. S. Shi, C. M. Wu, H. Y. Yang, and H. L. Wu. 2003. Thrombomodulin-mediated cell adhesion: involvement of its lectin-like domain. J. Biol. Chem. 278: 46750-46759.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 46750-46759
-
-
Huang, H.C.1
Shi, G.Y.2
Jiang, S.J.3
Shi, C.S.4
Wu, C.M.5
Yang, H.Y.6
Wu, H.L.7
-
16
-
-
78049363900
-
Downregulation of thrombomodulin, a novel target of Snail, induces tumorigenesis through epithelial-mesenchymal transition
-
Kao, Y. C., L. W. Wu, C. S. Shi, C. H. Chu, C. W. Huang, C. P. Kuo, H. M. Sheu, G. Y. Shi, and H. L. Wu. 2010. Downregulation of thrombomodulin, a novel target of Snail, induces tumorigenesis through epithelial-mesenchymal transition. Mol. Cell. Biol. 30: 4767-4785.
-
(2010)
Mol. Cell. Biol.
, vol.30
, pp. 4767-4785
-
-
Kao, Y.C.1
Wu, L.W.2
Shi, C.S.3
Chu, C.H.4
Huang, C.W.5
Kuo, C.P.6
Sheu, H.M.7
Shi, G.Y.8
Wu, H.L.9
-
17
-
-
0022396035
-
Thrombomodulin is present in human plasma and urine
-
Ishii, H., and P. W. Majerus. 1985. Thrombomodulin is present in human plasma and urine. J. Clin. Invest. 76: 2178-2181. (Pubitemid 16155511)
-
(1985)
Journal of Clinical Investigation
, vol.76
, Issue.6
, pp. 2178-2181
-
-
Ishii, H.1
Majerus, P.W.2
-
18
-
-
20244382267
-
Evidence of human thrombomodulin domain as a novel angiogenic factor
-
DOI 10.1161/01.CIR.0000160364.05405.B5
-
Shi, C. S., G. Y. Shi, Y. S. Chang, H. S. Han, C. H. Kuo, C. Liu, H. C. Huang, Y. J. Chang, P. S. Chen, and H. L. Wu. 2005. Evidence of human thrombomodulin domain as a novel angiogenic factor. Circulation 111: 1627-1636. (Pubitemid 40525162)
-
(2005)
Circulation
, vol.111
, Issue.13
, pp. 1627-1636
-
-
Shi, C.-S.1
Shi, G.-Y.2
Chang, Y.-S.3
Han, H.-S.4
Kuo, C.-H.5
Liu, C.6
Huang, H.-C.7
Chang, Y.-J.8
Chen, P.-S.9
Wu, H.-L.10
-
19
-
-
55749115786
-
Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response
-
Shi, C. S., G. Y. Shi, S. M. Hsiao, Y. C. Kao, K. L. Kuo, C. Y. Ma, C. H. Kuo, B. I. Chang, C. F. Chang, C. H. Lin, et al. 2008. Lectin-like domain of thrombomodulin binds to its specific ligand Lewis Y antigen and neutralizes lipopolysaccharide-induced inflammatory response. Blood 112: 3661-3670.
-
(2008)
Blood
, vol.112
, pp. 3661-3670
-
-
Shi, C.S.1
Shi, G.Y.2
Hsiao, S.M.3
Kao, Y.C.4
Kuo, K.L.5
Ma, C.Y.6
Kuo, C.H.7
Chang, B.I.8
Chang, C.F.9
Lin, C.H.10
-
20
-
-
0026328854
-
Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages
-
McCachren, S. S., J. Diggs, J. B. Weinberg, and W. A. Dittman. 1991. Thrombomodulin expression by human blood monocytes and by human synovial tissue lining macrophages. Blood 78: 3128-3132.
-
(1991)
Blood
, vol.78
, pp. 3128-3132
-
-
McCachren, S.S.1
Diggs, J.2
Weinberg, J.B.3
Dittman, W.A.4
-
21
-
-
0029873131
-
A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes
-
Grey, S. T., andW. W. Hancock. 1996. A physiologic anti-inflammatory pathway based on thrombomodulin expression and generation of activated protein C by human mononuclear phagocytes. J. Immunol. 156: 2256-2263. (Pubitemid 26087456)
-
(1996)
Journal of Immunology
, vol.156
, Issue.6
, pp. 2256-2263
-
-
Grey, S.T.1
Hancock, W.W.2
-
22
-
-
33846928462
-
Lipopolysaccharide down-regulates the thrombomodulin expression of peripheral blood monocytes: Effect of serum on thrombomodulin expression in the THP-1 monocytic cell line
-
DOI 10.1097/MBC.0b013e32801481cb, PII 0000172120070300000011
-
Kim, H. K., J. E. Kim, J. Chung, Y. T. Kim, S. H. Kang, K. S. Han, and H. I. Cho. 2007. Lipopolysaccharide down-regulates the thrombomodulin expression of peripheral blood monocytes: effect of serum on thrombomodulin expression in the THP-1 monocytic cell line. Blood Coagul. Fibrinolysis 18: 157-164. (Pubitemid 46232837)
-
(2007)
Blood Coagulation and Fibrinolysis
, vol.18
, Issue.2
, pp. 157-164
-
-
Kim, H.K.1
Kim, J.-E.2
Chung, J.3
Kim, Y.T.4
Kang, S.-H.5
Han, K.-S.6
Cho, H.-I.7
-
23
-
-
0033177995
-
Conditional gene targeting in macrophages and granulocytes using LysMcre mice
-
DOI 10.1023/A:1008942828960
-
Clausen, B. E., C. Burkhardt, W. Reith, R. Renkawitz, and I. Förster. 1999. Conditional gene targeting in macrophages and granulocytes using LysMcre mice. Transgenic Res. 8: 265-277. (Pubitemid 29523965)
-
(1999)
Transgenic Research
, vol.8
, Issue.4
, pp. 265-277
-
-
Clausen, B.E.1
Burkhardt, C.2
Reith, W.3
Renkawitz, R.4
Forster, I.5
-
24
-
-
35548932872
-
A global double-fluorescent cre reporter mouse
-
DOI 10.1002/dvg.20335
-
Muzumdar, M. D., B. Tasic, K. Miyamichi, L. Li, and L. Luo. 2007. A global double-fluorescent Cre reporter mouse. Genesis 45: 593-605. (Pubitemid 350013057)
-
(2007)
Genesis
, vol.45
, Issue.9
, pp. 593-605
-
-
Muzumdar, M.D.1
Tasic, B.2
Miyamichi, K.3
Li, N.4
Luo, L.5
-
25
-
-
61449154547
-
Immunodesign of experimental sepsis by cecal ligation and puncture
-
Rittirsch, D.,M. S. Huber-Lang, M. A. Flierl, and P. A.Ward. 2009. Immunodesign of experimental sepsis by cecal ligation and puncture. Nat. Protoc. 4: 31-36.
-
(2009)
Nat. Protoc.
, vol.4
, pp. 31-36
-
-
Rittirsch, D.1
Huber-Lang, M.S.2
Flierl, M.A.3
Ward, P.A.4
-
26
-
-
0036301797
-
Essential role of MD-2 in LPS responsiveness and TLR4 distribution
-
DOI 10.1038/ni809
-
Nagai, Y., S. Akashi, M. Nagafuku, M. Ogata, Y. Iwakura, S. Akira, T. Kitamura, A. Kosugi, M. Kimoto, and K. Miyake. 2002. Essential role of MD-2 in LPS responsiveness and TLR4 distribution. Nat. Immunol. 3: 667-672. (Pubitemid 34752476)
-
(2002)
Nature Immunology
, vol.3
, Issue.7
, pp. 667-672
-
-
Nagai, Y.1
Akashi, S.2
Nagafuku, M.3
Ogata, M.4
Iwakura, Y.5
Akira, S.6
Kitamura, T.7
Kosugi, A.8
Kimoto, M.9
Miyake, K.10
-
27
-
-
0029919991
-
Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice
-
DOI 10.1016/S1074-7613(00)80254-X
-
Haziot, A., E. Ferrero, F. Köntgen, N. Hijiya, S. Yamamoto, J. Silver, C. L. Stewart, and S. M. Goyert. 1996. Resistance to endotoxin shock and reduced dissemination of gram-negative bacteria in CD14-deficient mice. Immunity 4: 407-414. (Pubitemid 26174055)
-
(1996)
Immunity
, vol.4
, Issue.4
, pp. 407-414
-
-
Haziot, A.1
Ferrero, E.2
Kontgen, F.3
Hijiya, N.4
Yamamoto, S.5
Silver, J.6
Stewart, C.L.7
Goyert, S.M.8
-
28
-
-
0035863740
-
Induction of a novel mechanism of accelerated bacterial clearance by lipopolysaccharide in CD14-deficient and toll-like receptor 4-deficient mice
-
Haziot, A., N. Hijiya, S. C. Gangloff, J. Silver, and S. M. Goyert. 2001. Induction of a novel mechanism of accelerated bacterial clearance by lipopolysaccharide in CD14-deficient and Toll-like receptor 4-deficient mice. J. Immunol. 166: 1075-1078. (Pubitemid 32060265)
-
(2001)
Journal of Immunology
, vol.166
, Issue.2
, pp. 1075-1078
-
-
Haziot, A.1
Hijiya, N.2
Gangloff, S.C.3
Silver, J.4
Goyert, S.M.5
-
29
-
-
0029160975
-
Increased plasma levels of soluble thrombomodulin in patients with sepsis and organ failure
-
Iba, T., Y. Yagi, A. Kidokoro, M. Fukunaga, and T. Fukunaga. 1995. Increased plasma levels of soluble thrombomodulin in patients with sepsis and organ failure. Surg. Today 25: 585-590.
-
(1995)
Surg. Today
, vol.25
, pp. 585-590
-
-
Iba, T.1
Yagi, Y.2
Kidokoro, A.3
Fukunaga, M.4
Fukunaga, T.5
|