Relationship between the affinity of PEO-PPO-PEO block copolymers for biological membranes and their cellular effects

Pharmaceutical Research

Volumn 29, Issue 7, 2012, Pages 1908-1918

  Redhead, Martin ^a   Mantovani, Giuseppe ^a   Nawaz, Selina ^b   Carbone, Paola ^b   Gorecki, Dariusz C ^c   Alexander, Cameron ^a   Bosquillon, Cynthia ^a  

^a UNIVERSITY OF NOTTINGHAM   (United Kingdom)

^b UNIVERSITY OF MANCHESTER   (United Kingdom)

^c UNIVERSITY OF PORTSMOUTH   (United Kingdom)

Author keywords

biocompatibility; drug delivery; haemolysis; membrane; pluronics

Indexed keywords

COPOLYMER; LACTATE DEHYDROGENASE; POLY(ETHYLENE OXIDE) (PROPYLENE OXIDE) COPOLYMER; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; BIOTRANSFORMATION; CELL MEMBRANE; CELL METABOLISM; CHEMICAL COMPOSITION; CONTROLLED STUDY; CYTOTOXICITY TEST; ENZYME RELEASE; ERYTHROCYTE; HUMAN; HUMAN CELL; MEMBRANE BINDING; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL;

BIOCOMPATIBLE MATERIALS; CACO-2 CELLS; CELL LINE; CELL MEMBRANE; CELL SURVIVAL; DRUG CARRIERS; ERYTHROCYTES; HEMOLYSIS; HUMANS; L-LACTATE DEHYDROGENASE; MEMBRANE POTENTIAL, MITOCHONDRIAL; POLYETHYLENE GLYCOLS; PROPYLENE GLYCOLS;

EID: 84862600433     PISSN: 07248741     EISSN: 1573904X     Source Type: Journal    
DOI: 10.1007/s11095-012-0716-6     Document Type: Article

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