Regulation of olfactory transduction in the orco channel

Frontiers in Cellular Neuroscience

Volumn , Issue OCTOBER, 2011, Pages 1-2

  Martin, Fernando ^a   Alcorta, Esther ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP DEPENDENT PROTEIN KINASE; DIACYLGLYCEROL; INOSITOL 1,4,5 TRISPHOSPHATE; ION CHANNEL; ORCO CHANNEL; PHOSPHOLIPASE C; PROTEIN KINASE C; UNCLASSIFIED DRUG;

ARTICLE; DOWN REGULATION; DROSOPHILA MELANOGASTER; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; NONHUMAN; OLFACTORY DISCRIMINATION; OLFACTORY RECEPTOR; OLFACTORY TRANSDUCTION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; REGULATORY MECHANISM; SENSORY NERVE; SIGNAL TRANSDUCTION; SMELLING; UPREGULATION;

EID: 84862599513     PISSN: 16625102     EISSN: None     Source Type: Journal    
DOI: 10.3389/fncel.2011.00021     Document Type: Article

References (24)

1. Benton, R., Sachse, S., Michnick, S. W., and Vosshall, L. B. (2006). Atypical membrane topology and heteromeric function of Drosophila odorant receptors in vivo. PLoS Biol. 4, e20. doi: 10.1371/journal.pbio.0040020
2. Chatterjee, A., Roman, G., and Hardin, P. E. (2009). Go contributes to olfactory reception in Drosophila melanogaster. BMC Physiol. 9, 22. doi: 10.1186/1472-6793-9-22
3. Clyne, P., Warr, C., Freeman, M., Lessing, D., Kim, J., and Carlson, J. (1999). A novel family of divergent seven-transmembrane proteins: candidate odorant receptors in Drosophila. Neuron 22, 327-338.
4. de Bruyne, M., Foster, K., and Carlson, J. R. (2001). Odor coding in the Drosophila antenna. Neuron 30, 537-552.
5. Deng, Y., Zhang, W., Farhat, K., Oberland, S., Gisselmann, G., and Neuhaus, E. M. (2011). The stimulatory Gα(s) protein is involved in olfactory signal transduction in Drosophila. PLoS ONE 6, e18605. doi: 10.1371/journal.pone.0018605
6. Fishilevich, E., and Vosshall, L. B. (2005). Genetic and functional subdivision of the Drosophila antennal lobe. Curr. Biol. 15, 1548-1553.
7. Gomez-Diaz, C., Martin, F., and Alcorta, E. (2006). The inositol 1,4,5-triphosphate kinase1 gene affects olfac- tory reception in Drosophila melanogaster. Behav. Genet. 36, 309-321.
8. Hallem, E. A., and Carlson, J. R. (2004). The odor coding system of Drosophila. Trends Genet. 20, 453-459.
9. Hallem, E. A., and Carlson, J. R. (2006). Coding of odors by a receptor repertoire. Cell 125, 143-160.
10. Hallem, E. A., Ho, M. G., and Carlson, J. R. (2004). The molecular basis of odor coding in the Drosophila antenna. Cell 117, 965-979.
11. Hardie, R. C., Martin, F., Cochrane, G. W., Juusola, M., Georgiev, P., and Raghu, P. (2002). Molecular basis of amplification in Drosophila phototransduction: roles for G protein, phospholipase C, and diacylglycerol kinase. Neuron 36, 689-701.
12. Kain, P., Chakraborty, T. S., Sundaram, S., Siddiqi, O., Rodrigues, V., and Hasan, G. (2008). Reduced odor responses from antennal neurons of Gqa, phospho-lipase Cb, and rdgA mutants in Drosophila support a role for a phospholipid intermediate in insectol factory transduction. J. Neurosci. 28, 4745-4755.
13. Lundin, C., Kall, L., Kreher, S. A., Kapp, K., Sonnhammer, E. L., Carlson, J. R., Heijne, G., and Nilsson, I. (2007). Membrane topology of the Drosophila OR83b odorant receptor. FEBS Lett. 581, 5601-5604.
14. Nakagawa, T., and Vosshall, L. B. (2009). Controversy and consensus: noncanonical signaling mechanisms in the insect olfactory system. Curr. Opin. Neurobiol.19, 284-292.
15. Sato, K., Pellegrino, M., Nakagawa, T., Nakagawa, T., Vosshall, L. B., and Touhara, K. (2008). Insect olfactory receptors are heteromeric ligand-gated ion channels. Nature 452, 1002-1006.
16. Smart, R., Kiely, A., Beale, M., Vargas, E., Carraher, C., Kralicek, A. V., Christie, D. L., Chen, C., Newcomb, R. D., and Warr, C. G. (2008). Drosophila odorant receptors are novel seven transmembrane domain proteins that can signal independently of heterotrimeric G proteins. Insect Biochem. Mol. Biol. 38, 770-780.
17. Vogl, A., Noe, J., Breer, H., and Boekhoff, I. (2000). Cross-talk between olfactory second messenger pathways. Eur. J. Biochem. 267, 4529-4535.
18. Vosshall, L. B., Amrein, H., Morozov, P. S., Rzhetsky, A., and Axel, R. (1999). A spatial map of olfactory receptor expression in the Drosophila antenna. Cell 96, 725-736.
19. Vosshall, L. B., and Hansson, B. S. (2011). A unified nomenclature system for the insect olfactory co-receptor. Chem. Senses 36, 497-498.
20. Vosshall, L. B., and Stocker, R. F. (2007). Molecular architecture of smell and taste in Drosophila. Annu. Rev. Neurosci. 30, 505-533.
21. Wicher, D. (2010). Design principles of sensory receptors. Front. Cell. Neurosci. 4:25. doi: 10.3389/fncel.2010.00025
22. Wicher, D., Schäfer, R., Bauernfeind, R., Stensmyr, M. C., Heller, R., Heinemann, S. H., and Hansson, B. S. (2008). Drosophila odorant receptors are both ligandgated and cyclic-nucleotide-activated cation channels. Nature 452, 1007-1011.
23. Wicher, D., Schäfer, R., Bauernfeind, R., Stensmyr, M. C., Heller, R., Heinemann, S. H., and Hansson, B. S. (2009). dOr83b - receptor or ion channel?. Ann. N. Y. Acad. Sci. 1170, 164-167.
24. Yao, C. A., and Carlson, J. R. (2010). Role of G-proteins in odor-sensing and CO2-sensing neurons in Drosophila. J. Neurosci. 30, 4562-4572.