Thrombosis from a prothrombin mutation conveying antithrombin resistance

New England Journal of Medicine

Volumn 366, Issue 25, 2012, Pages 2390-2396

  Miyawaki, Yuhri ^a   Suzuki, Atsuo ^a   Fujita, Junko ^a   Maki, Asuka ^a   Okuyama, Eriko ^a   Murata, Moe ^a   Takagi, Akira ^a,b   Murate, Takashi ^a,b   Kunishima, Shinji ^c,d   Sakai, Michio ^f   Okamoto, Kohji ^f   Matsushita, Tadashi ^e   Naoe, Tomoki ^a   Saito, Hidehiko ^d   Kojima, Tetsuhito ^a,b  

^a NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b NAGOYA UNIVERSITY   (Japan)

^c Clinical Research Center   (Japan)

^d NATIONAL HOSPITAL ORGANIZATION NAGOYA MEDICAL CENTER   (Japan)

^e NAGOYA UNIVERSITY HOSPITAL   (Japan)

^f UNIVERSITY OF OCCUPATIONAL AND ENVIRONMENTAL HEALTH   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

ANTITHROMBIN; ARGININE; LEUCINE; PROTHROMBIN; RECOMBINANT PROTEIN; RECOMBINANT PROTHROMBIN; UNCLASSIFIED DRUG; WARFARIN;

ADOLESCENT; AMINO ACID SUBSTITUTION; ARTICLE; CARBOXYLATION; CASE REPORT; COMPLEX FORMATION; DEEP VEIN THROMBOSIS; DISEASE PREDISPOSITION; DRUG RESISTANCE; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; GAIN OF FUNCTION MUTATION; GENE; HETEROZYGOSITY; HUMAN; HUMAN CELL; MISSENSE MUTATION; MUTATIONAL ANALYSIS; PEDIGREE ANALYSIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTHROMBIN GENE; RESTRICTION FRAGMENT LENGTH POLYMORPHISM;

EID: 84862585039     PISSN: 00284793     EISSN: 15334406     Source Type: Journal    
DOI: 10.1056/NEJMoa1201994     Document Type: Article

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