The spiroindolone drug candidate NITD609 potently inhibits gametocytogenesis and blocks Plasmodium falciparum transmission to Anopheles mosquito vector

Antimicrobial Agents and Chemotherapy

Volumn 56, Issue 7, 2012, Pages 3544-3548

  Van Pelt Koops, J C ^a   Pett, H E ^a   Graumans, W ^a   Van Der Vegte Bolmer, M ^a   Van Gemert, G J ^a   Rottmann, M ^b,d   Yeung, B K S ^c   Diagana, T T ^c   Sauerwein, R W ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

^c NOVARTIS INSTITUTE FOR TROPICAL DISEASES   (Singapore)

^d UNIVERSITY OF BASEL   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIMALARIAL AGENT; ARTEMETHER; BENFLUMETOL; INDOLE DERIVATIVE; NITD 609; PRIMAQUINE; UNCLASSIFIED DRUG;

ANOPHELES; ANTIMALARIAL ACTIVITY; ARTICLE; CELL MATURATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG EFFICACY; GAMETOCYTE; HUMAN; HUMAN CELL; IC 50; IN VITRO STUDY; NONHUMAN; PARASITE CONTROL; PARASITE TRANSMISSION; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

ANIMALS; ANOPHELES; ANTIMALARIALS; GAMETOGENESIS; INDOLES; INSECT VECTORS; PLASMODIUM FALCIPARUM; SPIRO COMPOUNDS;

EID: 84862571445     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.06377-11     Document Type: Article

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