Mechanically stable lipid bilayers in Teflon-coated silicon chips for single-channel recordings

Micro and Nanosystems

Volumn 4, Issue 1, 2012, Pages 2-7

  Oshima, Azusa ^a   Hirano Iwata, Ayumi ^a,b   Nasu, Tomohiro ^a   Kimura, Yasuo ^a   Niwano, Michio ^a  

^a TOHOKU UNIVERSITY   (Japan)

^b JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Microfabrication; Planar bilayer lipid membranes; Single channel recording; Teflon fabrication

Indexed keywords

APPLIED VOLTAGES; BILAYER LIPID MEMBRANE; BIOLOGICAL CHANNELS; CURRENT TRANSIENTS; HIGH-THROUGHPUT ANALYSIS; INSULATOR COATINGS; INSULATOR LAYER; ION CHANNEL; ISOTROPIC ETCHING; LOW NOISE; LOW-PASS FILTERING; MECHANICAL SHOCK; MECHANICALLY STABLE; PLANAR BILAYERS; SI CHIPS; SI SUBSTRATES; SILICON CHIP; SINGLE CHANNEL RECORDING;

CELL MEMBRANES; COATINGS; ELECTRIC PROPERTIES; ELECTROPHYSIOLOGY; LIPID BILAYERS; MICROANALYSIS; MICROFABRICATION; POLYTETRAFLUOROETHYLENES; POWER QUALITY; SILICA; SILICON NITRIDE; SILICON OXIDES;

SILICON;

EID: 84862570701     PISSN: 18764029     EISSN: 18764037     Source Type: Journal    
DOI: 10.2174/1876402911204010002     Document Type: Article

References (29)

1. Overington, J.P.; Al-Lazikani, B.; Hopkins, A.L. How many drug targets are there? Nat. Rev. Drug Discov., 2006, 5, 993-996.
2. Mathie, A. Ion channels as novel therapeutic targets in the treatment of pain. J. Pharm. Pharmacol., 2010, 62, 1089-1095.
3. Miller, C. Ion Channel Reconstitution; Plenum Press: New York, 1986.
4. Sugawara, M.; Hirano, A.; Bühlmann, P.; Umezawa, Y. Design and application of ion-channel sensors based on biological and artificial receptors. Bull. Chem. Soc. Jpn., 2002, 75, 187-201.
5. Hirano-Iwata, A.; Niwano, M.; Sugawara, M. The design of molecular sensing interfaces with lipid-bilayer assemblies. Trends Anal. Chem., 2008, 27, 512-520.
6. Schmidt, C.; Mayer, M.; Vogel, H. A chip-based biosensor for the functional analysis of single ion channels. Angew. Chem. Int. Ed. 2000, 39, 3137-3140.
7. Wilk, S.J.; Petrossian, L.; Goryll, M.; Thornton, T.J.; Goodnick, S.M.; Tang, J.M.; Eisenberg, R.S. Integrated electrodes on a silicon based ion channel measurement platform. Biosens. Bioelectron., 2007, 23, 183-190.
8. Maurer, J.A.; White, V.E.; Dougherty, D.A.; Nadeau, J.L. Reconstitution of ion channels in agarose-supported silicon orifices. Biosens. Bioelectron., 2007, 22, 2577-2584.
9. Liu, B.; Rieck, D.; Wie, B.J.V.; Cheng, G.J.; Moffett, D.F.; Kidwell, D.A. Bilayer lipid membrane (BLM) based ion selective electrodes at the meso-, micro-, and nano-scales. Biosens. Bioelectron., 2009, 24, 1843-1849.
10. Römer W.; Steinem, C. Impedance analysis and single-channel recordings on nano-black lipid membranes based on porous alumina. Biophys. J., 2004, 86, 955-965.
11. Han, X.; Studer, A.; Sehr, H.; Geissbühler, I.; Berardino, M.D.; Winkler, F. K.; Tiefenauer, L. X. Nanopore arrays for stable and functional free-standing lipid bilayers. Adv. Mater., 2007, 19, 4466-4470.
12. Ide, T.; Ichikawa, T. A novel method for artificial lipid-bilayer formation. Biosens. Bioelectron., 2005, 21, 672-677.
13. Shim, J. W.; Gu, L. Q. Stochastic sensing on a modular chip containing a single-ion channel. Anal. Chem., 2007, 79, 2207-2213.
14. Hirano-Iwata, A.; Aoto, K.; Oshima, A.; Taira, T.; Yamaguchi, R.; Kimura, Y.; Niwano, M. Free-standing lipid bilayers in silicon chips-membrane stabilization based on microfabricated apertures with a nanometer-scale smoothness. Langmuir, 2010, 26, 1949-1952.
15. Sugawara, M.; Hirano, A.; Rehák, M.; Nakanishi, J.; Kawai, K.; Sato, H.; Umezawa, Y. Electrochemical evaluation of chemical selectivity of glutamate receptor ion channel proteins with a multichannel sensor. Biosens. Bioelectron., 1997, 12, 425-439.
16. Gu, L.-Q.; Braha, O.; Conlan, S.; Cheley, S.; Bayley, H. Stochastic sensing of organic analytes by a pore-forming protein containing a molecular adapter. Nature, 1999, 398, 686-690.
17. Coronado R.; Lattore, R. Biophys. J. Phospholipid bilayers made from monolayers on patch-clamp pipettes., 1983, 43, 231-236.
18. Hirano, A.; Wakabayashi, M.; Matsuno, Y.; Sugawara, M. A single-channel sensor based on gramicidin controlled by molecular recognition at bilayer lipid membranes containing receptor. Biosens. Bioelectron., 2003, 18, 973-983.
19. Minami, H.; Sugawara, M.; Odashima, K.; Umezawa, Y.; Uto, M.; Michaelis, E. K.; Kuwana, T. Ion channel sensors for glutamic acid. Anal. Chem., 1991, 63, 2787-2795.
20. Mayer, M.; Kriebel, J. K.; Tosteson, M. T.; Whitesides, G. M. Microfabricated Teflon membranes for low-noise recordings of ion channels in planar lipid bilayers. Biophys. J., 2003, 85, 2684-2695.
21. Peterman, M.C.; Ziebarth, J.M.; Braha, O.; Bayley, H.; Fishman, H.A.; Bloom, D.M. Ion channels and lipid bilayer membranes under high potentials using microfabricated apertures. Biomed. Microdev., 2002, 4, 231-236.
22. Woolley, G.A.; Wallace, B.A. Model ion channels: gramicidin and alamethicin. J. Membrane Biol., 1992, 129, 109-136.
23. Petrache, H. I.; Tristram-Nagle, S.; Nagle, J.F. Fluid phase structure of EPC and DMPC bilayers. Chem. Phys. Lipids, 1998, 95, 83-94.
24. Hara, M.; Yuan, H.; Yang, Q.; Hoshino, T.; Yokoyama, A.; Miyake, J. Stabilization of liposomal membranes by thermozeaxanthins: carotenoid-glucoside esters. Biochim. Biophys. Acta, 1999, 1461, 147-154.
25. Abdulreda M.H.; Moy, V.T. Atomic force microscope studies of the fusion of floating lipid bilayers. Biophys. J., 2007, 92, 4369-4378.
26. Hirano-Iwata, A.; Taira, T.; Oshima, A.; Kimura, Y.; Niwano, M. Improved stability of free-standing lipid bilayers based on nanoporous alumina films. Appl. Phys. Lett. 2010, 96, 213706.
27. Andersen, O.S. Ion movement through gramicidin A channels. Biophys. J., 1983, 41, 119-133.
28. 13 gramicidin A channels. Biophys. J., 1998, 75, 2830-2844.
29. Sansom, M. S. P. The biophysics of peptide models of ion channels. Prog. Biophys. Mol. Biol., 1991, 55, 139-235.