Subthreshold desensitization of human basophils re-capitulates the loss of Syk and FcεRI expression characterized by other methods of desensitization

Clinical and Experimental Allergy

Volumn 42, Issue 7, 2012, Pages 1060-1070

  MacGlashan, Jr ^a  

^a JOHNS HOPKINS ASTHMA AND ALLERGY CENTER   (United States)

Author keywords

Allergy; Basophil; Fc Receptors; Human; Syk

Indexed keywords

CALCIUM; CBL PROTEIN; FC EPSILON RECEPTOR RI; FC RECEPTOR; IMMUNOGLOBULIN E ANTIBODY; IMMUNOGLOBULIN E RECEPTOR; INTERLEUKIN 3; INTERLEUKIN 4; MITOGEN ACTIVATED PROTEIN KINASE; PROTEIN KINASE LYN; PROTEIN KINASE SYK; UNCLASSIFIED DRUG;

ARTICLE; BASOPHIL; CONCENTRATION (PARAMETERS); CYTOKINE RELEASE; CYTOSOL; DESENSITIZATION; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HISTAMINE RELEASE; HUMAN; HUMAN CELL; HUMAN CELL CULTURE; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SUBTHRESHOLD DESENSITIZATION;

ANTIBODIES; BASOPHILS; CELLS, CULTURED; DESENSITIZATION, IMMUNOLOGIC; DRUG HYPERSENSITIVITY; GENE EXPRESSION REGULATION; HISTAMINE; HUMANS; INTERLEUKIN-3; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; PROTEIN-TYROSINE KINASES; RECEPTORS, IGE; SIGNAL TRANSDUCTION;

EID: 84862568570     PISSN: 09547894     EISSN: 13652222     Source Type: Journal    
DOI: 10.1111/j.1365-2222.2012.04013.x     Document Type: Article

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