Preclinical characterization of 18F-D-FPHCys, a new amino acid-based PET tracer

European Journal of Nuclear Medicine and Molecular Imaging

Volumn 39, Issue 4, 2012, Pages 703-712

  Denoyer, Delphine ^a   Kirby, Laura ^a   Waldeck, Kelly ^a   Roselt, Peter ^a   Neels, Oliver C ^a   Bourdier, Thomas ^b   Shepherd, Rachael ^c   Katsifis, Andrew ^c   Hicks, Rodney J ^a,d  

^a PETER MACCALLUM CANCER CENTRE   (Australia)

^b ROYAL PRINCE ALFRED HOSPITAL   (Australia)

^c AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION   (Australia)

^d UNIVERSITY OF MELBOURNE   (Australia)

Author keywords

In vitro uptake; LAT1 amino acid transporters; S (3 18F fluoropropyl) D homocysteine; Small animal PET. Cancer imaging

Indexed keywords

ALANINE; AMINO ACID TRANSPORTER; CARBON 14; CYSTEINE; FLUOROPROPYL D HOMOCYSTEINE F 18; MESSENGER RNA; METHIONINE; RADIOPHARMACEUTICAL AGENT; SERINE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG; DIAGNOSTIC AGENT; DRUG DERIVATIVE; HOMOCYSTEINE; S (3 FLUOROPROPYL)HOMOCYSTEINE; S-(3-FLUOROPROPYL)HOMOCYSTEINE; TRACER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL GROWTH; CELL PROLIFERATION; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MOUSE; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PROSTATE CANCER; PROTEIN EXPRESSION; REAL TIME POLYMERASE CHAIN REACTION; RNA TRANSCRIPTION; SQUAMOUS CELL CARCINOMA; TUMOR XENOGRAFT; ANIMAL; CELL TRANSFORMATION; GENE EXPRESSION REGULATION; METABOLISM; METHODOLOGY; TRANSPORT AT THE CELLULAR LEVEL; TUMOR CELL LINE;

ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE, TUMOR; CELL PROLIFERATION; CELL TRANSFORMATION, NEOPLASTIC; GENE EXPRESSION REGULATION; HOMOCYSTEINE; HUMANS; LARGE NEUTRAL AMINO ACID-TRANSPORTER 1; MICE; POSITRON-EMISSION TOMOGRAPHY; RADIOACTIVE TRACERS;

EID: 84862565631     PISSN: 16197070     EISSN: 16197089     Source Type: Journal    
DOI: 10.1007/s00259-011-2017-4     Document Type: Article

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