Leishmanicidal compounds from the fruits of Piper longum

Planta Medica

Volumn 78, Issue 9, 2012, Pages 906-908

  Ghosal, Sabari ^a   Deb, Anindita ^b   Mishra, Priyanka ^a   Vishwakarma, Ram ^b  

^a AMITY UNIVERSITY   (India)

^b NATIONAL INSTITUTE OF IMMUNOLOGY   (India)

Author keywords

axenic amastigotes; Leishmania donovani; Piper longum; Piperaceae; piperlongumide; promastigotes

Indexed keywords

1 (3,4 METHYLENDIOXYPHENYL) 1E TETRADECENE; 2E,4E N ISOBUTYL DODECENAMIDE; 2E,4E N ISOBUTYL OCTADECENAMIDE; 2E,4E,12E 13 (3,4 PHENYL) TRIDECA TRIENOIC ACID ISOBUTYL AMIDE; PIPERLONGIMIN A [2E N ISOBUTYL HEXADECENAMIDE]; PIPERLONGIMIN B [2E OCTADECENOYLPIPERIDINE]; PLANT MEDICINAL PRODUCT; UNCLASSIFIED DRUG;

ARTICLE; DRUG STRUCTURE; LEISHMANIASIS; PIPER LONGUM; PROMASTIGOTE; TRADITIONAL MEDICINE;

ANTIPROTOZOAL AGENTS; BENZODIOXOLES; DRUG EVALUATION, PRECLINICAL; FATTY ACIDS, UNSATURATED; FRUIT; INHIBITORY CONCENTRATION 50; LEISHMANIA DONOVANI; MAGNETIC RESONANCE SPECTROSCOPY; MOLECULAR STRUCTURE; PIPER; STRUCTURE-ACTIVITY RELATIONSHIP;

LEISHMANIA DONOVANI; PIPER LONGUM; PIPERACEAE;

EID: 84862548462     PISSN: 00320943     EISSN: 14390221     Source Type: Journal    
DOI: 10.1055/s-0031-1298537     Document Type: Article

References (12)

1. Rocha LG, Almeida JRGS, Macedo RO, Barbosa-Filho JMA. A review of natural products with antileishmanial activity. Phytomedicine: 2005; 2 514 535 (Pubitemid 40755130)
2. Chan-Bacab MJ, Pena-Rodriguez LM. Plant natural products with leishmanicidal activity. Nat Prod Rep: 2010; 18 674 688
3. Kumar S, Arya P, Mukherjee C, Singh BK, Singh N, Parmar VS, Prasad AK, Ghosh B. Novel aromatic ester from Piper longum and its analogues inhibit expression of cell adhesion molecules on endothelial cells. Biochemistry: 2005; 44 15944 15952 (Pubitemid 41746926)
4. Parmar VS, Jain SC, Bisht KS, Jain R, Taneja P, Jha A, Tyagi OD, Prasad AK, Wengel J, Olsen CE, Boll PM. Phytochemistry of the genus Piper. Phytochemistry: 1997; 4 597 603
5. Mishra P, Sinha S, Guru SK, Bhushan S, Vishwakarma RA, Ghosal S. Two new amides with cytotoxic activity from the fruits of Piper longum. J Asian Nat Prod Res: 2011; 13 143 148
6. Singh SK, Bimal S, Narayan S, Jee E, Bimal D, Das P, Bimal R. Leishmania donovani: assessment of leishmanicidal effects of herbal extracts obtained from plants in the visceral leishmaniasis endemic area of Bihar, India. Exp Parasitol: 2011; 127 552 558
7. Kapil A. Piperine, a potent inhibitor of Leishmania donovani promastigotes in vitro. Planta Med: 1993; 59 475
8. Banerji A, Sarkar M, Datta R, Sengupta P, Abraham K. Amides from Piper brachystachyum and Piper retrofractum. Phytochemistry: 2002; 59 897 901 (Pubitemid 34406418)
9. Banerji A, Das C. Two amides from Piper brachystachyum. Phytochemistry: 1989; 28 3039 3042
10. Dutta A, Bandopadhyay S, Mandal C, Chatterjee M. Development of a modified MTT assay for screening antimonial resistant field isolates of Indian visceral leishmaniasis. Parasitol Int: 2005; 54 119 122 (Pubitemid 40615210)
11. Pan AA, Duboise SM, Eperon S, Rivas L, Hodgkinson V, Ttraub-Cseko Y, Mcmohan-Pratt D. Developmental life cycle of leishmania-cultivation and characterization of cultured extracellular amastigotes. J Eukaryot Microbiol: 1993; 40 213 223
12. Manandhar KD, Jadav TP, Prajapati VK, Kumar S, Rai M, Dube A, Srivastava ON, Sundar S. Antileishmanial activity of nano-amphotericine B deoxycholate. J Antimicrob Chemother: 2008; 62 376 380