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Volumn 43, Issue 7, 2012, Pages 1051-1060

Overexpression of astrocyte-elevated gene-1 is closely correlated with poor prognosis in human non-small cell lung cancer and mediates its metastasis through up-regulation of matrix metalloproteinase-9 expression

Author keywords

AEG 1; Lung cancer; Metastasis; MMP 2; MMP 9

Indexed keywords

GELATINASE A; GELATINASE B; SMALL INTERFERING RNA;

EID: 84862531654     PISSN: 00468177     EISSN: 15328392     Source Type: Journal    
DOI: 10.1016/j.humpath.2011.08.017     Document Type: Article
Times cited : (26)

References (31)
  • 2
    • 0025615213 scopus 로고
    • Lung cancer with a single brain metastasis: Therapeutic options
    • Rizzi A, Tondini M, Rocco G, et al. Lung cancer with a single brain metastasis: therapeutic options. Tumori 1990;76:579-89.
    • (1990) Tumori , vol.76 , pp. 579-589
    • Rizzi, A.1    Tondini, M.2    Rocco, G.3
  • 3
    • 0018636116 scopus 로고
    • CNS metastases in small cell bronchogenic carcinoma. Increasing frequency and changing pattern with lengthening survival
    • Nugent JL, Bunn Jr PA, Matthews MJ, et al. CNS metastases in small cell bronchogenic carcinoma. Increasing frequency and changing pattern with lengthening survival. Cancer 1979;44:1885-93.
    • (1979) Cancer , vol.44 , pp. 1885-1893
    • Nugent, J.L.1    Bunn Jr., P.A.2    Matthews, M.J.3
  • 4
    • 84981833366 scopus 로고
    • Metastatic tumors of the brain and their relation to primary and secondary cancer
    • Knights Jr EM. Metastatic tumors of the brain and their relation to primary and secondary cancer. Cancer 1954;7:259-65.
    • (1954) Cancer , vol.7 , pp. 259-265
    • Knights Jr., E.M.1
  • 5
    • 0033748034 scopus 로고    scopus 로고
    • RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genes
    • Jiang H, Kang DC, Alexandre D, et al. RaSH, a rapid subtraction hybridization approach for identifying and cloning differentially expressed genes. Proc Natl Acad Sci 2000;97:12684-9.
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 12684-12689
    • Jiang, H.1    Kang, D.C.2    Alexandre, D.3
  • 6
    • 0037118589 scopus 로고    scopus 로고
    • Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid subtraction hybridization, RaSH
    • Su ZZ, Kang DC, Chen Y, et al. Identification and cloning of human astrocyte genes displaying elevated expression after infection with HIV-1 or exposure to HIV-1 envelope glycoprotein by rapid subtraction hybridization, RaSH. Oncogene 2002;21:3592-602.
    • (2002) Oncogene , vol.21 , pp. 3592-3602
    • Su, Z.Z.1    Kang, D.C.2    Chen, Y.3
  • 7
    • 1842634484 scopus 로고    scopus 로고
    • Metadherin, a cell surface protein in breast tumors that mediate lung metastasis
    • Brown DM, Ruoslahti E. Metadherin, a cell surface protein in breast tumors that mediate lung metastasis. Cancer Cell 2004;5:365-74.
    • (2004) Cancer Cell , vol.5 , pp. 365-374
    • Brown, D.M.1    Ruoslahti, E.2
  • 8
    • 36849061266 scopus 로고    scopus 로고
    • Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity
    • Kikuno N, Shiina H, Urakami S, et al. Knockdown of astrocyte-elevated gene-1 inhibits prostate cancer progression through upregulation of FOXO3a activity. Oncogene 2007;26:7647-55.
    • (2007) Oncogene , vol.26 , pp. 7647-7655
    • Kikuno, N.1    Shiina, H.2    Urakami, S.3
  • 9
    • 65649143486 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression
    • Yoo BK, Emdad L, Su ZZ, et al. Astrocyte elevated gene-1 regulates hepatocellular carcinoma development and progression. J Clin Invest 2009;119:465-77.
    • (2009) J Clin Invest , vol.119 , pp. 465-477
    • Yoo, B.K.1    Emdad, L.2    Su, Z.Z.3
  • 10
    • 70350447686 scopus 로고    scopus 로고
    • Overexpression of AEG-1 significantly associates with tumor aggressiveness and poor prognosis in human non-small cell lung cancer
    • Song L, Li W, Zhang H, et al. Overexpression of AEG-1 significantly associates with tumor aggressiveness and poor prognosis in human non-small cell lung cancer. J Pathol 2009;219:317-26.
    • (2009) J Pathol , vol.219 , pp. 317-326
    • Song, L.1    Li, W.2    Zhang, H.3
  • 11
    • 65549113479 scopus 로고    scopus 로고
    • Overexpression of astrocyte elevated gene-1 (AEG-1) is associated with esophageal squamous cell carcinoma (ESCC) progression and pathogenesis
    • Yu C, Chen K, Zheng H, et al. Overexpression of astrocyte elevated gene-1 (AEG-1) is associated with esophageal squamous cell carcinoma (ESCC) progression and pathogenesis. Carcinogenesis 2009;30:894-901.
    • (2009) Carcinogenesis , vol.30 , pp. 894-901
    • Yu, C.1    Chen, K.2    Zheng, H.3
  • 12
    • 67650076377 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma
    • Lee SG, Jeon HY, Su ZZ, et al. Astrocyte elevated gene-1 contributes to the pathogenesis of neuroblastoma. Oncogene 2009;28:2476-84.
    • (2009) Oncogene , vol.28 , pp. 2476-2484
    • Lee, S.G.1    Jeon, H.Y.2    Su, Z.Z.3
  • 13
    • 57849134562 scopus 로고    scopus 로고
    • MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor prognosis breast cancer
    • Hu G, Chong RA, Yang Q, et al. MTDH activation by 8q22 genomic gain promotes chemoresistance and metastasis of poor prognosis breast cancer. Cancer Cell 2009;15:9-20.
    • (2009) Cancer Cell , vol.15 , pp. 9-20
    • Hu, G.1    Chong, R.A.2    Yang, Q.3
  • 14
    • 73949102954 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 (AEG-1): A novel target for human glioma therapy
    • Emdad L, Sarkar D, Lee SG, et al. Astrocyte elevated gene-1 (AEG-1): a novel target for human glioma therapy. Mol Cancer Ther 2010;9:79-88.
    • (2010) Mol Cancer Ther , vol.9 , pp. 79-88
    • Emdad, L.1    Sarkar, D.2    Lee, S.G.3
  • 15
    • 33751257780 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc
    • Lee SG, Su ZZ, Emdad L, et al. Astrocyte elevated gene-1 (AEG-1) is a target gene of oncogenic Ha-ras requiring phosphatidylinositol 3-kinase and c-Myc. Proc Natl Acad Sci U S A 2006;103:17390-5.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 17390-17395
    • Lee, S.G.1    Su, Z.Z.2    Emdad, L.3
  • 16
    • 32944459561 scopus 로고    scopus 로고
    • Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: Implications for tumor progression and metastasis
    • Emdad L, Sarkar D, Su ZZ, et al. Activation of the nuclear factor kappaB pathway by astrocyte elevated gene-1: implications for tumor progression and metastasis. Cancer Res 2006;66:1509-16.
    • (2006) Cancer Res , vol.66 , pp. 1509-1516
    • Emdad, L.1    Sarkar, D.2    Su, Z.Z.3
  • 17
    • 40449089338 scopus 로고    scopus 로고
    • Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1
    • Sarkar D, Park ES, Emdad L, et al. Molecular basis of nuclear factor-kappaB activation by astrocyte elevated gene-1. Cancer Res 2008;68:1478-84.
    • (2008) Cancer Res , vol.68 , pp. 1478-1484
    • Sarkar, D.1    Park, E.S.2    Emdad, L.3
  • 18
    • 0020314366 scopus 로고
    • Analysis of type 5 adenovirus transformation with a cloned rat embryo cell line (CREF)
    • Fisher PB, Babiss LE, Weinstein IB, et al. Analysis of type 5 adenovirus transformation with a cloned rat embryo cell line (CREF). Proc Natl Acad Sci U S A 1982;79:3527-31.
    • (1982) Proc Natl Acad Sci U S A , vol.79 , pp. 3527-3531
    • Fisher, P.B.1    Babiss, L.E.2    Weinstein, I.B.3
  • 19
    • 50649124445 scopus 로고    scopus 로고
    • Deleted in pancreatic carcinoma locus4/Smad4 participates in the regulation of apoptosis by affecting the Bcl-2/Bax balance in non-small cell lung cancer
    • Ke Z, Zhang X, Ma L, et al. Deleted in pancreatic carcinoma locus4/Smad4 participates in the regulation of apoptosis by affecting the Bcl-2/Bax balance in non-small cell lung cancer. HUM PATHOL 2008;39:1438-45.
    • (2008) Hum Pathol , vol.39 , pp. 1438-1445
    • Ke, Z.1    Zhang, X.2    Ma, L.3
  • 20
    • 20444389341 scopus 로고    scopus 로고
    • Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1
    • Kang DC, Su ZZ, Sarkar D, et al. Cloning and characterization of HIV-1-inducible astrocyte elevated gene-1, AEG-1. Gene 2005;353:8-15.
    • (2005) Gene , vol.353 , pp. 8-15
    • Kang, D.C.1    Su, Z.Z.2    Sarkar, D.3
  • 21
    • 50349090038 scopus 로고    scopus 로고
    • Astrocyte elevated gene-1 (AEG-1) is a novel prognostic marker for breast cancer progression and overall patient survival
    • Li J, Zhang N, Song LB, et al. Astrocyte elevated gene-1 (AEG-1) is a novel prognostic marker for breast cancer progression and overall patient survival. Clin Cancer Res 2008;14:3319-26.
    • (2008) Clin Cancer Res , vol.14 , pp. 3319-3326
    • Li, J.1    Zhang, N.2    Song, L.B.3
  • 22
    • 34147165551 scopus 로고    scopus 로고
    • Astrocyte elevated gene (AEG)-1: Recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration
    • Emdad L, Sarkar D, Su ZZ, et al. Astrocyte elevated gene (AEG)-1: recent insights into a novel gene involved in tumor progression, metastasis and neurodegeneration. Pharmacol Ther 2007;14:155-70.
    • (2007) Pharmacol Ther , vol.14 , pp. 155-170
    • Emdad, L.1    Sarkar, D.2    Su, Z.Z.3
  • 23
    • 77951879469 scopus 로고    scopus 로고
    • Clinical significance of astrocyte elevated gene-1 expression in human oligodendrogliomas
    • Xia Z, Zhang N, Jin H, et al. Clinical significance of astrocyte elevated gene-1 expression in human oligodendrogliomas. Clin Neurol Neurosurg 2010;112:413-9.
    • (2010) Clin Neurol Neurosurg , vol.112 , pp. 413-419
    • Xia, Z.1    Zhang, N.2    Jin, H.3
  • 25
    • 0027281052 scopus 로고
    • Primary human adult lung epithelial cells in vitro: Response to interferon-γ and cytomegalovirus
    • Ibrahim L, Dominguez M, Yacoub M. Primary human adult lung epithelial cells in vitro: response to interferon-γ and cytomegalovirus. Immunology 1993;79:119-24.
    • (1993) Immunology , vol.79 , pp. 119-124
    • Ibrahim, L.1    Dominguez, M.2    Yacoub, M.3
  • 26
    • 0028114985 scopus 로고
    • The implications of angiogenesis for the biology and therapy of cancer metastasis
    • Fidler IJ, Ellis LM. The implications of angiogenesis for the biology and therapy of cancer metastasis. Cell 1994;79:185-8.
    • (1994) Cell , vol.79 , pp. 185-188
    • Fidler, I.J.1    Ellis, L.M.2
  • 27
    • 0036561908 scopus 로고    scopus 로고
    • Modelling the molecular circuitry of cancer
    • Hahn WC, Weinberg RA. Modelling the molecular circuitry of cancer. Nat Rev Cancer 2002;2:331-41.
    • (2002) Nat Rev Cancer , vol.2 , pp. 331-341
    • Hahn, W.C.1    Weinberg, R.A.2
  • 29
    • 0345643514 scopus 로고    scopus 로고
    • Regulation of matrix metalloproteinase expression in tumor invasion
    • Westermarck J, Kähäri VM. Regulation of matrix metalloproteinase expression in tumor invasion. FASEB J 1999;13:781-92.
    • (1999) FASEB J , vol.13 , pp. 781-792
    • Westermarck, J.1    Kähäri, V.M.2
  • 30
    • 2942717090 scopus 로고    scopus 로고
    • Signaling pathways responsible for cancer cell invasion as targets for cancer therapy
    • Sliva D. Signaling pathways responsible for cancer cell invasion as targets for cancer therapy. Curr Cancer Drug Targets 2004;4:327-36.
    • (2004) Curr Cancer Drug Targets , vol.4 , pp. 327-336
    • Sliva, D.1
  • 31
    • 0028346025 scopus 로고
    • Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells
    • Bernhard EJ, Gruber SB, Muschel RJ. Direct evidence linking expression of matrix metalloproteinase 9 (92-kDa gelatinase/collagenase) to the metastatic phenotype in transformed rat embryo cells. Proc Natl Acad Sci U S A 1994;91:4293-7.
    • (1994) Proc Natl Acad Sci U S A , vol.91 , pp. 4293-4297
    • Bernhard, E.J.1    Gruber, S.B.2    Muschel, R.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.